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Home Molecules Methylprednisone / Methylprednisolone

Methylprednisone / Methylprednisolone

Molecule Description

Methylprednisolone is a steroid hormone required by the body for multiple functions.

Uses of Methylprednisone / Methylprednisolone

Methylprednisolone is used to treat a variety of conditions including lung diseases like asthma, chronic obstructive pulmonary disease, acute bronchitis, joint diseases like arthritis, skin diseases eczema, intestine diseases like Crohn’s disease and ulcerative colitis or multiple sclerosis.

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Contraindications of Methylprednisone / Methylprednisolone

When should one not use Methylprednisone / Methylprednisolone

Allergic reaction to Methylprednisolone
Diabetes mellitus
If you had recently taken any vaccine
Increased blood pressure

Side effects of Methylprednisone / Methylprednisolone

Common side effects of this drug are:

Nausea, vomiting, stomach pain, diarrhea
Ulcers in the stomach that can bleed
Increased risk of getting infection
Reduced sleep
Mental health problems- Feeling depressed, suicidal thoughts, anxiety, seeing or feeling things that don’t exist
Changes in menstrual cycles
Allergic reactions such as skin rash, swelling of the face or wheezing and difficulty breathing
Blood clots or thrombosis in a leg vein
High blood pressure
Muscle weakness
Swelling, increased water and salt content in the body
Muscle cramps
Blurred vision, Increased pressure in the eye
Delayed growth in children
Increased appetite and weight gain
Worsening of existing diabetes
Acne

Precautions and Warnings of Methylprednisone / Methylprednisolone

Pregnancy

Can I take Methylprednisone / Methylprednisolone during pregnancy?

This medicine should be avoided in pregnancy. This medicine crosses the placenta and can affect the baby, so it is unsafe to use during pregnancy. This medicine can slow the growth of the baby. If you are on this medicine and if you happen to be pregnant, do not stop this medicine abruptly on your own. Consult your doctor immediately.

Breast Feeding

Can I take Methylprednisone / Methylprednisolone while breastfeeding?

It is unsafe to use this medicine if you are breastfeeding, it can pass into the breast milk and can affect the growth of baby.

Driving

Can I drive if I have consumed Methylprednisone / Methylprednisolone?

Methylprednisolone does not affect your ability to drive. It can cause some people dizziness or vision problems. In such a scenario, avoid driving.

Alcohol

Can I consume alcohol with Methylprednisone / Methylprednisolone?

No known interaction with alcohol.

Other General Warnings

Talk to your doctor if

You have bleeding problems
Blood clots
Brittle bones (osteoporosis)
Diabetes eye diseases (such as cataracts, glaucoma, infection of the eye)
Heart problems (such as recent heart attack, congestive heart failure)
Kidney disease, liver disease
Stomach ulcer
Tuberculosis
Tumour of adrenal gland tissue - Pheochromocytoma
Mental/ mood conditions (such as psychosis, depression, anxiety)
Stomach problems

Interactions of Methylprednisone / Methylprednisolone

Interactions with other medicines

Aspirin
Rifampin
Phenytoin
Phenobarbital
Ketoconazole
Erythromycin
Digoxin
Inform your doctor if you have recently taken any vaccine

Interactions with food items

Grapefruit or its juice may interact with Methylprednisolone and lead to unwanted side effects.

Dietary Restrictions of Methylprednisone / Methylprednisolone

Potassium supplements is necessary.

Dosage of Methylprednisone / Methylprednisolone

Overdose

Inform your doctor immediately in case of overdose. Symptoms of Methylprednisolone overdose can include (especially over long term overdose): altered mental status with agitation (psychosis), burning or itching skin, fits, deafness, depression, dry skin, high blood pressure, increased risk of infection, muscle weakness, nausea and vomiting, swelling in lower legs, ankles or feet, weak bones (osteoporosis) and bone fractures (seen with long-term use), weakness, nervousness, sleepiness, etc. Few of your existing health conditions such as acid reflux, ulcers and diabetes may worsen. In case you suspect acute or long term overdose symptoms, seek emergency medical attention immediately.

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Missed a Dose

If you missed any dose, take it as soon as you remember. Skip the missed dose if it is time for your next dose & do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Mahesh Muthe

MBBS

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Any precautions before I start treatment?

A: Inform your doctor if you have diabetes mellitus as Methylprednisolone may increase sugar levels. Inform your doctor if you have recently received any live vaccine such as Measle Mumps and Rubella (MMR), chickenpox or flu.

References

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Last Updated on: 24 Dec 2020 | 01:48 PM (IST)

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Disclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.

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