Losartan

Molecule Description

Losartan belongs to a group of medicines which lower increased blood pressure (

Angiotensin-II receptor antagonists).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Losartan

High blood pressure
Chronic heart failure
Heart attack (myocardial infarction) causing dysfunction of left lower chamber of the heart
Diabetic kidney disease

Contraindications of Losartan

When should one not use Losartan

Pregnancy
Allergic to the Losartan or any other ARAs
Renal Artery Stenosis (a condition where a blood vessel in the kidney is narrow)
Liver problems
Kidney disease

Side effects of Losartan

Common side effects of this drug are:

Excessive drop in blood pressure
Headache, and dizziness
Can cause allergic reactions like rash, swelling of face, lips and throat (serious). In such a scenario, seek emergency medical help
High levels of potassium in the blood
Vertigo
Low blood sugar
Fatigue
Changes in kidney function including kidney failure
Reduced number of red blood cells (anemia)
Can cause skeletal muscle injury called rhabdomyolysis. Hence, report if you experience fever or pain/ tenderness

Precautions and Warnings of Losartan

Pregnancy

Can I take Losartan during pregnancy?

Losartan can harm the fetus seriously. Do not take Losartan if you are pregnant or planning a pregnancy.

Breast Feeding

Can I take Losartan while breastfeeding?

Losartan is not recommended for breastfeeding mothers. There is no sufficient data available to say whether Losartan can be harmful to the nursing infant if breastfed by a mother who is on Losartan. But it is advisable to seek a physician’s help to find a safer alternative.

Driving

Can I drive if I have consumed Losartan?

Losartan is not known to affect your driving ability. If you experience dizziness or drowsiness with Losartan, avoid driving.

Alcohol

Can I consume alcohol with Losartan?

Caution is advised as alcohol can the blood pressure level and can increase side effects like sedation or drowsiness.

Other General Warnings

Talk to your doctor if

History of angioedema (swelling of the face, lips, throat, tongue)
Excessive vomiting or diarrhea
If you are known to have narrowing or blockage of the blood vessels leading to your kidneys or had a kidney transplant recently
Liver disease
You suffer from heart failure with or without renal impairment or concomitant severe life-threatening cardiac arrhythmias
Heart disease
If you have high blood pressure and diabetes-related kidney problems. Your doctor shall regularly ask you to do kidney tests and test for electrolytes (e.g. potassium)

Mode of Action of Losartan

How Does It Work?

Angiotensin-II is a substance produced in the body which causes constriction of blood vessels. This leads to an increase in blood pressure. Losartan prevents the binding of Angiotensin-II to it’s rece...

Interactions of Losartan

Interactions with other medicines

Many medicines are known to interact; hence any prescription that the patient is taking has to be reported
Aspirin and NSAIDs reduce the action of Losartan on blood pressure
All ACE inhibitors, Azathioprine, Lithium, Aspirin, and Aliskiren should be avoided
Medicines which are known to increase potassium levels like Diuretics

Interactions with food items

No information is available on interactions of Losartan when taken with food, consult your doctor or pharmacist for further information.

Dietary Restrictions of Losartan

Avoid high potassium-containing foods (spinach, banana, peas, kidney beans). Low-salt diet is preferred. Avoid fruits, foods and health supplements with high potassium contents.

Dosage of Losartan

Overdose

Overdose symptoms can include increased heart rate, extremely low blood pressure, dizziness, increased levels of potassium in the blood, kidney failure and loss of consciousness. Seek immediate emerge...

Missed a Dose

Consume missed dose as soon as you remember it. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take extra doses to compensate for a missed one.

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I inform my healthcare expert before I start treatment with Losartan?

A: You must give an account of your past and present diseases, especially diabetes, and all the ongoing medications, supplements and herbal medicines that you are taking. If you take antidiabetic medicines or insulin, track your blood sugar carefully while taking Losartan, particularly during the first month of its use. The combination of these diabetes medicines when on Losartan may cause a significant change in your blood sugar levels owing to drug-drug interactions. Aspirin and painkillers also diminish the positive effect on blood pressure of Losartan. Hence, sharing complete history is of utmost importance.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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