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Molecule Description

Almotriptan belongs to a class of medications called selective Serotonin Receptor Agonists.

Uses of Almotriptan

Sensitive (short-lasting) treatment of migraine attacks, with a history of migraine with or without aura in adults.

Contraindications of Almotriptan

When should one not use Almotriptan

  • Do not take if you are allergic to Almotriptan or any ingredient of this medicine
  • Do not take this medicine if a person with known or suspected heart disease (reduced blood flow in vessels of heart)
  • Do not take this medicine if you have had a stroke or experienced a reduction in the blood flow to the brain
  • If you have had obstruction of the large arteries in the arms or legs (peripheral vascular disease)
  • Do not take this medicine if you are taking other medicines which used to treat migraines including Ergotamine, Dihydroergotamine, and Methysergide or other Serotonin Agonists (e.g., Sumatriptan)
  • Do not take this medicine if you are suffering from severe liver disease

Side effects of Almotriptan

Common side effects of this drug are:

  • Excessive sleep
  • Nausea
  • Vomiting
  • Tiredness
  • Dizziness

Precautions and Warnings of Almotriptan


Can I take Almotriptan during pregnancy?
It is probably unsafe to use this medicine during pregnancy. Take only when prescribed by your doctor.

Breast Feeding

Can I take Almotriptan while breastfeeding?
It is unsafe to use this medicine during breastfeeding. Do not breastfeed your baby for 24 hours after taking this medicine.


Can I drive if I have consumed Almotriptan?
Taking this medicine may lead to cause sleepiness or tiredness. If you are affected, do not drive.


Can I consume alcohol with Almotriptan?
Avoid alcohol with this medicine; it may lead to newer and worse headaches.

Other General Warnings

Talk to your doctor if
  • You are suffering from under-active thyroid
  • You have heart diseases
  • You have severe liver disorders
  • You have a history of stroke
  • You have high blood pressure
  • You have uncontrolled diabetes
  • You have severe kidney disease
  • You are taking medicines including prescription medicines, non-prescription medicines, and herbal products

Mode of Action of Almotriptan

How Does It Work?

Almotriptan works by reducing the inflammatory response concerned with migraines by binding to certain specific Serotonin Receptors in the brain blood vessels and causing them to narrow.

Interactions of Almotriptan

Interactions with other medicines

  • Both the classes of medicines:
  • Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Noradrenaline Reuptake Inhibitors (SNRIs), if taken concomitantly with almotriptan, may lead to a serious condition called “Serotonin Syndrome.”
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  • Ketoconazole
  • Dihydroergotamine
  • Ergotamine Tartrate
  • Other Triptans

Interactions with food items

No information is available on interactions of Almotriptan when taken with food, consult your doctor or pharmacist for further details.

Dietary Restrictions of Almotriptan

No information is available on dietary restrictions while you are taking Almotriptan, consult your doctor or pharmacist for further details.

Dosage of Almotriptan


Overdosing can lead to a state of heavy sleepiness. More severe symptoms may include high blood pressure or heart-related problems. If you are suspecting an overdose, seek emergency medical care immediately. It is essential to try and keep the airway patent for adequate oxygenation and ventilation in a person with a suspected overdose.
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Missed a Dose

Take the missed dose as soon as you remember. If it is the time for next dose, skip the missed dose and follow regular dosing schedule.

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare provider before taking Almotriptan?

A: Give a detailed account of your medical and surgical history. Also, tell your doctor all the prescription and non-prescription medicines, herbal preparations, and nutritional supplements that you may be taking. After taking Almotriptan, notify your physician if your migraines are occurring more frequently. Also, inform if you are taking Almotriptan for consecutive three months.

Q: Is there anything else that I need to know before taking Almotriptan?

A: For best results, use Almotriptan as soon as the migraine attack begins. Lying down in a dark and quiet room may help relieve migraines faster. Avoid driving or operating heavy machinery after taking Almotriptan as it can lead to dizziness and drowsiness.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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