Mefenamic Acid+Paracetamol / Acetaminophen

Molecule Description

Mefenamic Acid+Paracetamol is a combination medicine. It is used to provide symp...
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Uses of Mefenamic Acid+Paracetamol / Acetaminophen

Mefenamic Acid+Paracetamol is used to relieve mild to moderate pain such as headache, migraine, toothache, muscle ache, backache, traumatic pain, pain due to sprain and strain and pain after surgeries...
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Contraindications of Mefenamic Acid+Paracetamol / Acetaminophen

When should one not use Mefenamic Acid+Paracetamol / Acetaminophen

  • If you are allergic to mefenamic acid, paracetamol or similar medicines
  • If you have asthma or have had an asthmatic attack due to painkillers
  • If you are suffering from inflammation in the digestive tract
  • If you had or have stomach ulcers
  • It should not be used in the last trimester of pregnancy
  • It should not be used for managing pain before, during and after coronary bypass surgery

Side effects of Mefenamic Acid+Paracetamol / Acetaminophen

Common side effects of this drug are:

  • Diarrhoea
  • Drowsiness
  • Nausea
  • Vomiting
  • Stomach pain
  • Indigestion
  • Skin rash

Precautions and Warnings of Mefenamic Acid+Paracetamol / Acetaminophen



Can I take mefenamic acid+paracetamol during pregnancy?
Mefenamic acid+Paracetamol should not be used during pregnancy or if you are planning to conceive, consult your doctor before using it.

Breast Feeding

Can I take mefenamic acid+paracetamol while breastfeeding?
Mefenamic acid+Paracetamol can be taken while breastfeeding, if prescribed by the doctor.


Can I drive if I have consumed mefenamic acid+paracetamol?
Mefenamic acid+Paracetamol may cause drowsiness, thus you need to be cautious while driving.


Can I consume alcohol with mefenamic acid+paracetamol?
Avoid consuming alcohol with mefenamic acid+paracetamol, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if
  • You have problems with your liver or kidneys
  • You have a heart condition like stroke, heart failure or myocardial infarction
  • You have high blood pressure
  • You have a history of asthma or allergic reactions
  • You have ulcer in your stomach or intestine or perforations in digestive tract
  • You have fluid retention in your body

Mode of Action of Mefenamic Acid+Paracetamol / Acetaminophen

How Does It Work?

Mefenamic acid+Paracetamol work by blocking the production of a chemical substance (prostaglandin) responsible for pain, inflammation and swelling

Interactions of Mefenamic Acid+Paracetamol / Acetaminophen

Interactions with other medicines

  • Some medicines can affect the way mefenamic acid+paracetamol works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat your heart problems, diabetes, infections, nausea or vomiting or are taking medicines like blood thinners, water pills, cholesterol-lowering medicines, ...
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  • Cholesterol-lowering medicines like Colestyramine should be taken with a minimum gap of 2 hours.
  • This combination should not be taken for 8 to 12 days after taking a medicine called Mifepristone.
  • Digoxin used to treat heart failure should not be taken along with this combination.

Dosage of Mefenamic Acid+Paracetamol / Acetaminophen


Symptoms of overdose may include nausea, vomiting, stomach pain, headache, drowsiness. Seek urgent medical help if you suspect an overdose.

Missed a Dose

If you have missed any dose of mefenamic acid+paracetamol then take it as soon as you remember. If it is already time for the next dose then skip the missed dose and follow the regular dosing schedule...
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: In which all dosage forms is mefenamic acid+paracetamol available?

A: Mefenamic acid+Paracetamol is available in the form of tablet, syrup, suspension, oral liquid.

Q: Are there any side effects of using mefenamic acid+paracetamol?

A: You may experience drowsiness, nausea, vomiting, diarrhoea, stomach pain after taking mefenamic acid+paracetamol.
Last Updated on: 19 Nov 2021 | 10:55 AM (IST)

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