Nimesulide+Paracetamol / Acetaminophen
Description
Nimesulide + Paracetamol is a combination medicine used to relieve different ki
nds of pain, such as headache, ear pain, period pain, and joint pain. It also helps bring down the fever. These medicines work together to reduce the chemical substances in the body that cause pain, swelling, and high temperature, making you feel more comfortable. This combination is available in various forms, including tablets, syrup, suspension, oral liquid, and gel, so the doctor can choose the most suitable option for your condition. Before starting Nimesulide + Paracetamol, it is important to tell your doctor if you are pregnant, planning to get pregnant, or breastfeeding. You should also inform them of all other medicines, supplements, or herbal products you are taking, as well as any health conditions you may have. This helps ensure the treatment is safe for you and prevents any unwanted side effects or interactions.
Uses
- Nimesulide+Paracetamol is used to relieve pain in conditions such as toothache, ear pain, joint pain, headache, pain during menses, etc.
- It is also used in fever.
Contraindications
When should one not use Nimesulide+Paracetamol / Acetaminophen
- If you are allergic to nimesulide or paracetamol.
- If you have problems with your liver or kidneys.
- If you have flu, fever, chills and shivering.
- If you have a history of liver damage induced by medicines like nimesulide.
- If you had or have stomach bleeding, ulcer and inflammation of stomach lining.
- If you have problems related to blood clotting, bleeding disorders.
- If you have serious heart failure problems or heart-related disorders.
- It should not be used in patients less than 12 years old, pregnant women or breastfeeding mothers.
Side effects
Common side effects of this drug are:
- Nausea
- Vomiting
- Diarrhoea
- Application site reactions
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have problems with your heart, liver, kidneys
- You have a history of stomach or intestine ulcers
- You have nausea, stomach pain, loss of appetite, weakness
- You develop black tarry stools or vomit blood
- You are above 60 years old
- You are scheduled to have a surgery
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Some medicines can affect the way Nimesulide+Paracetamol works or this medicine itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction....
- Especially if you are taking medicines to treat your heart problems, psychiatric illnesses, cancer, gout, infections or are taking medicines like blood thinners, steroids, medicines used to modify the immune system during organ transplant....
Content Details
Dr. Mansi Savla
B. Pharm, PharmD
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Can Nimesulide+Paracetamol be used for menstrual pains?
Q: In which all dosage forms is Nimesulide+Paracetamol available?
References
- NIMESULIDE [Internet]. Ema.europa.eu. 2021 [cited 19 Nov 2025]
- Anadin Paracetamol Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 19 Nov 2025]
- Anadin Paracetamol Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 19 Nov 2025]









