Thioril 50mg Tablet
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Thioril 50 MG Description
Thioril tablets are used to treat symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). It is used in people who have already been treated with at least two other medications without success. Thioril tablets are not the first-line treatment for schizophrenia. The active ingredient in Thioril 50 mg tablets is Thioridazine. It belongs to the conventional antipsychotics class of medication. The mode of action of Thioril 50 mg tablets is by decreasing abnormal excitement in the brain. The other uses of Thioril 50 mg tablets include managing depression with psychotic features, behavioural disorders in children, and psychoneurotic conditions in older adults. Some of the major side effects of Thioril 50 mg tablets include irregular heartbeat and heart rhythm (QTc prolongation), leading to sudden death. This is a life-threatening side effect of this medicine, and therefore, it is used only when other medications have not worked. In case of sudden palpitations, irregular heartbeat, dizziness, and fainting spell, the user should immediately seek medical help....
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|Uses||chizophrenia, Depression associated with anxiety, Behavioural problems in children|
|Side effects||Sleepiness, Dryness in mouth, Abnormality of voluntary movements, Weight gain, Increased prolactin level in blood, Urinary retention, Constipation, Muscle stiffness, Tremors|
Check more medicines with composition as Thioridazine(50.0 Mg)
Uses of Thioril 50 MG
- As per the USFDA, Thioril tablets are used in:
- Management of schizophrenia with psychotic manifestations, such as hallucinations, delusions, etc.
- Short-term management of depression in varying degrees of Generalised Anxiety Disorder
- Management of severe behavioural problems in children
Contraindications of Thioril 50 MG
- Do not take Thioril tablets or use with caution:
- If you are allergic to Thioridazine, an ingredient in Thioril tablets
- If you are on other antipsychotic medications
- If you have a history of heart rhythm disorders; this medication can cause changes in the heartbeat (such as QT prolongation), which can lead to death
- If you are planning for a pregnancy or currently expecting
- If you are an older adult with dementia (memory loss) and psychosis
- If you have a history of nervous system disorders, such as seizures (fits)
- If you are taking Levodopa to treat Parkinson's disease (psychotic condition)
- If you have Tardive Dyskinesia (irreversible and involuntary body movements)
- If you have Neuroleptic Malignant Syndrome (a fatal and complex condition)
- If you have a tumour in your adrenal gland (a condition called pheochromocytoma), or if you have been diagnosed with a prolactin-dependent tumour; this medicine can increase prolactin levels
- If you have low potassium or other electrolyte imbalances, which may precipitate heart conditions
Side effects of Thioril 50 MG
- Side effects of Thioril tablets include:
- Weight gain
- Stuffy nose
- Pale skin
- Blurred vision
- Dry mouth
Precautions and Warnings of Thioril 50 MG
Can I take Thioril tablets during pregnancy?
No. Thioril tablets can be harmful to the foetus, especially if used in the third trimester of the pregnancy. The new-born may have abnormal muscle movements and withdrawal symptoms, such as shaking, fluctuations in muscle stiffness, drowsiness, and breathing troubles. Consult your doctor before taking Thioril tablets in pregnancy.
Can I take Thioril tablets while breastfeeding?
Thioril tablets are probably unsafe for nursing mothers. Limited human data suggest that this medicine may pass into breast milk. Please consult your doctor before using Thioril medication if you are nursing.
Can I drive if I have taken a Thioril tablet?
Do not drive after taking a Thioril tablet as it can cause adverse effects like sleepiness, lightheadedness, slow reflexes, and blurred vision, affecting your ability to drive.
Can I consume alcohol with Thioril tablets?
Avoid consuming alcohol with Thioril tablets. It can interfere with the function of this medicine and cause increased side effects like drowsiness.
Other General Warnings
Talk to your doctor if
- You have heart-related symptoms such as fast, irregular, or pounding heartbeat; dizziness; lightheadedness; or fainting. They can be the result of serious rhythm disorders.
- You experience severe sweating, diarrhoea, or vomiting. This can lead to potassium or magnesium electrolyte imbalance.
- You have a bleeding disorder or are on a blood thinner medication.
- You use any medications like opioid pain relievers that cause sedation or tranquillisation.
- You are diagnosed with a seizure disorder, drug or alcohol overdose, severe drowsiness, and other nervous system-related problems.
- You have blood cell-related problems, like low white blood cell count (leukopenia or neutropenia).
- You have a heart condition or had a stroke.
- You have any suicidal or self-harming thoughts and sudden mood changes.
- You use herbal or Ayurvedic medicines or supplements.
- You are an older adult over 65.
Mode of Action of Thioril 50 MG
How Does It Work?
Thioril tablet consists of Thioridazine as its active ingredient. It belongs to the class of medicines known as conventional antipsychotics. Thioridazine works by increasing dopamine activity by blocking its receptors. This chemical messenger is responsible for mood, ability, and cognitive behaviour. By intercepting these receptors, the effect of these substances lasts longer, which helps improve the positive symptoms of schizophrenia, such as hallucinations, delusions, etc....
Directions for Use of Thioril 50 MG
- Try to take Thioril tablets exactly as prescribed by the doctor.
- Do not exceed the dosage of Thioril tablets, even if you cannot notice its effects.
- Take this medicine without breaking or chewing it.
- Do not use it with other medications without notifying your doctor.
- Do not take this medicine if its packaging has been already opened.
- Do not abruptly stop using Thioril tablets, as this can cause adverse effects from withdrawal.
Interactions of Thioril 50 MG
Interactions with other medicines
- Do not take any medications that may cause slow or irregular heartbeat, high or low blood pressure, changes in heart rate, and other heart-related conditions.
- Avoid medicines like diuretics and laxatives that lower blood potassium or magnesium levels because Thioril tablets can further lower potassium levels and cause severe heart rhythm disorders.
- Thioril tablets are recommended along with other antipsychotic, antidepressant, or anti-seizure medications. Using Thioril tablets with these medicines can cause severe adverse effects.
- Try to be cautious with the dosage of Thioril tablets if using opioid pain relievers, sedatives, heart medicines, antimalarial medicines, antihistamines (cetirizine), etc. They can interact with Thioril tablets and cause increased drowsiness and other side effects....
- Using propranolol with Thioril tablets can increase the plasma concentration of Thioridazine in the body and cause overdose symptoms.
Interactions with food items
- Try to avoid eating spicy food while on treatment with Thioril tablets. It is recommended to take an easily digestible diet.
Storage and disposal of Thioril 50 MG
Store Thioril tablets in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the tablets. Dispose of the packaging carefully after use. Do not flush extra or expired tablets down the toilet....
Dosage of Thioril 50 MG
Thioril tablet overdose can lead to symptoms like dizziness, tremors, agitation, convulsion, nausea, vomiting, hypotension, increased heart rate, sleep disturbances, confusion, diminished reflexes, and coma. If you overdose on Thioril tablets and experience these symptoms, immediately seek emergency medical treatment from a hospital close to you....
Missed a Dose
If you have missed a dose of Thioril tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with your regular dosing schedule. Do not take both of them together; this can lead to adverse reactions....
Frequently Asked Questions (FAQs)
Q: Can I take Thioril tablets if I have not undergone other treatments for schizophrenia?
A: No, Thioril tablets are not the first medicines used in people with schizophrenia. If at least two sets of medications have failed to show results, Thioril tablets are used. Also, these tablets have severe side effects, so the risk of using these medications is high. Hence, doctors prescribe them only in emergencies. Do not use them without consulting your doctor.
Q: Is it possible for me to gain weight after using Thioril tablets?
A: Yes, Thioril tablets are associated with weight gain and appetite changes, similar to other antipsychotic medications. However, this side effect may not be seen in every user. If you notice any fluctuations in your weight, try exercising regularly and maintaining a healthy diet.
Q: Are Thioril tablets habit-forming?
A: No, like most antipsychotic medications, Thioril tablets are not habit-forming. They do not cause physical or cognitive dependency in users. However, do not suddenly stop using them as this can result in withdrawal symptoms like tremors, shaking, profuse sweating, etc.
- New Drugs Approved by CDSCO [Internet]. cdscoonline.gov.in. 2022 [cited 10 Mar 2022] -
- Thioridazine: Medlineplus drug information [Internet]. U.S. National Library of Medicine. medlineplus.gov [cited 10 Mar 2022] -
- Thioridazine [Internet]. Drugs and Lactation Database (LactMed) [Internet]. U.S. National Library of Medicine. Ncbi.nlm.nih.gov. [cited 10 Mar 2022] -
- Thioridazine [Internet]. Uses, Interactions, Mechanism of Action. go.drugbank.com [cited 10 Mar 2022]
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Table of Contents Is exercise good for varicocele?5 Exercises for varicoceleExercise to avoid varicoceleConclusionFAQs Varicocele is when an enlargement occurs in the veins of the scrotum which is a thin pouch of skin tissue surrounding the testicles. These veins carry oxygen-poor blood back to the heart from the testicles. Varicoceles occur if the blood collects
Varicocele – Symptoms, Causes, Home Remedies
Table of Contents What causes varicocele?Symptoms of varicoceleHome remedies for varicoceleWhen to seek professional help for varicocele?ConclusionFAQs Varicocele is a condition that affects 10%-15% of adult men and chances may be higher in younger males. Varicocele is a similar condition to varicose veins except it occurs in the scrotum. The male reproductive organs include the
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