Riz Plus Tab

10 Tablet(s) in Strip
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Risperidone(3.0 Mg) + Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg)
Therapeutic classification

Medical Description

Riz Plus tablet is primarily used to treat psychotic disorders like schizophrenia and bipolar disorder. Managing irritability in autistic children, manic episodes, etc., are other uses of Riz Plus tab...
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Uses of Riz Plus Tab

  • As per USFDA, Riz Plus tablet is an antipsychotic medicine indicated for the treatment of:
  • Schizophrenia in adults and adolescents; this medicine lowers hallucination, delusions, cognitive problems, lack of pleasure, memory problems, etc., which are both positive and negative symptoms.
  • Short-term treatment of acute manic or mixed episodes associated with bipolar disorder in adults, children and adolescents aged 10-17 years.
  • Irritability in autistic children and adolescents aged 5-16 years.

Contraindications of Riz Plus Tab

  • If you are allergic to the risperidone component of Riz Plus tablet
  • If you are an elderly patient with dementia-related psychosis. There is an increased risk of death.
  • If you are diagnosed with the neuroleptic malignant syndrome (a neuromuscular disorder).
  • If you have tardive dyskinesia (abrupt jerky movements).
  • If you are going through treatment with other antipsychotic medicines.
  • If you were diagnosed with any type of seizure disorder.
  • If you have a history of diabetes and uncontrolled glucose levels.
  • If you have a tumour on your adrenal gland (a condition called pheochromocytoma), or if you have been diagnosed with 'a prolactin-dependent tumour'. This medicine can increase prolactin levels.
  • If you have a low white blood cell count (leukopenia or neutropenia).
  • If you are under treatment for Parkinson's disease or dementia with Lewy bodies.
  • If you are diagnosed with an adrenal gland tumour, Riz Plus tablet can cause life-threatening high blood pressure.
  • If you are expecting currently or are planning a pregnancy.

Side effects of Riz Plus Tab

  • Increase in appetite
  • Fatigue
  • Upper respiratory tract infection
  • Vomiting
  • Increased saliva production
  • Constipation
  • Anxiety

Precautions and Warnings of Riz Plus Tab


Can I take Riz Plus tablets during pregnancy?
No. Riz Plus Tablets can be unsafe during pregnancy. There are limited studies available that concluded its safety in humans. However, a few studies on animal subjects have shown harmful effects on the foetus. Do not take Riz Plus tablets without medical consultation.

Breast Feeding

Can I take Riz Plus tablets while breastfeeding?
No. Riz Plus tablets are probably unsafe to use if you are breastfeeding. Some human data suggest that this medicine may pass into breast milk. Please consult your doctor before using Riz Plus medication as a nursing mother.


Can I drive if I have taken a Riz Plus tablet?
No. Do not drive after taking Riz Plus tablets. This medicine can cause side effects like sleepiness, dizziness, blurred vision, and diminished reflexes that affect the person’s ability to drive and operate heavy machinery.


Can I consume alcohol with Riz Plus tablets?
No. Do not consume alcohol with Riz Plus tablets. It can alter the effectiveness of this medicine. It can also cause side effects such as dizziness, drowsiness, etc.

Other General Warnings

Talk to your doctor if
  • You have suicidal and self-harming thoughts.
  • You are using any herbal or Ayurvedic medicines ; some of them can interfere with this medicine.
  • You are an older adult over 65; the effects of this medicine can be exaggerated in this age group. Use with caution.
  • You have diabetes; keep a check on your blood glucose levels as this medicine can cause changes in blood glucose levels.
  • You have low blood pressure; it causes orthostatic hypotension (sudden lowering of blood pressure).
  • You have priapism (prolonged erection of the penis).

Mode of Action of Riz Plus Tab

How Does It Work?

Riz Plus Tablet contains risperidone and trihexyphenidyl as its active components. Risperidone belongs to the group of medicines called atypical antipsychotics. It works by improving dopamine and ...
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Directions for Use of Riz Plus Tab

  • Take Riz Plus tablets exactly as prescribed by the doctor.
  • Do not exceed the prescribed dosage of Riz Plus medicine, even if you cannot feel its effects.
  • Swallow the tablet as a whole with a glass of water; do not break or chew it.
  • Do not try to take it with other medicines without informing your doctor.
  • Take Riz Plus tablets with or without food.
  • Do not use this medication if the package has been already opened.
  • Do not suddenly stop taking Riz Plus tablets as this can cause adverse effects.
  • You can take Riz plus tablets with or without consuming food.

Interactions of Riz Plus Tab

Interactions with other medicines

  • There is no information available on the interaction of food with Riz plus Tablet. You can take this tablet before or after consuming a meal.

Interactions with food items

  • Riz Plus tablets with levodopa (used for Parkinson's disease) may have opposite effects.
  • Use caution if you take medicines that lower high blood pressure; the combination of these two medicines can cause very low blood pressure.
  • Use caution if you take medicines that lower potassium in the body, like laxatives, diuretics, etc.; Riz Plus tablets can lower potassium further and cause side effects.
  • Medicines like fluoxetine and paroxetine can increase the levels of Riz Plus medicine in the body.
  • Use caution if you use other sedatives, antimalarials, cardiac medicines, anti-allergy medicines, etc. On interaction, all of them can cause increased drowsiness.
  • Use caution if you take tablets that lower heart rate; Riz Plus can further reduce the heart rate.
  • Other antipsychotics, anti-seizure medications, or antidepressants along with Riz Plus tablets can result in severe effects.

Storage and disposal of Riz Plus Tab

Store Riz Plus tablets in dry conditions and at room temperature. Keep these medicines away from wet surfaces, direct sunlight, and humidity. Keep Riz Plus Tablets away from children and pets. Di...
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Dosage of Riz Plus Tab


Riz Plus tablet overdose can cause dizziness, agitation, tremors, convulsion, vomiting, increased heart rate, low blood pressure, sleep disturbances, slow reflexes, and loss of consciousness. If you o...
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Missed a Dose

If you have missed a single dose of the Riz Plus tablet, take it as soon as you recall. If you remember when it is time to take the next dose, take the scheduled dose and skip the missed one. Do not t...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can Riz Plus tablets cause weight gain if I use them regularly?

A: Riz Plus tablets are associated with weight gain, though it varies from person to person. But most commonly, users of this medication notice weight gain in a few weeks. If you see any difference in your weight, try exercising and eating healthy food.

Q: Can I take Riz Plus tablets if I have diabetes?

A: Riz Plus tablets can fluctuate blood sugar levels. Regularly monitor your blood sugar levels when on this medication. If you have diabetes or uncontrolled blood sugar levels, use this medicine with caution and inform your doctor.

Q: Can Riz Plus tablets cause dependency or addiction issues if I take them for a long time?

A: Riz Plus Tablets are not addictive and do not cause any dependency issues. But suddenly stopping this medicine can cause withdrawal problems such as difficulty sleeping, feeling or being sick, sweating, irritation, and uncontrollable muscle movements. Speak with your doctor if you wish to stop this medicine or experience these symptoms. You might feel sleepy in the first few days after starting treatment with Riz Plus tablets.
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ContainsRisperidone(3.0 Mg),Trihexyphenidyl / Benzhexol Hydrochloride(2.0 Mg)
UsesSchizophrenia, Acute mania in bipolar disorder, Irritability in autistic children
Side effectsIncrease in appetite, Fatigue, Upper respiratory tract infection, Vomiting, Increased saliva, Constipation, Anxiety, Urinary incontinence
Last Updated on: 30 Mar 2022 | 10:25 AM (IST)
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