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Depsonil Dz Tablet

10 Tablet(s) in Strip
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Depsonil Dz Tablet Description

Depsonil Dz is used for the treatment of major depressive disorders. Major depressive disorder or depression is a mood disorder characterised by sadness, loss of interest, mood swings, hopelessness a

nd loneliness etc. Depsonil Dz contains Imipramine and Diazepam as the active ingredient. Imipramine is an antidepressant that regulates the chemical messenger called Serotonin and norepinephrine, whereas Diazepam produces calming, sedative effects on the brain. Depsonil Dz dosage should be taken as advised by your doctor. This medicine should not be taken without consulting a doctor as there are many side effects associated with this medicine. Do not stop taking this medicine suddenly without consulting your doctor, as it can cause clinical worsening of your condition or may lead to withdrawal symptoms.


Product Summary

Offer Price₹15.84
You Save₹2.16 (12% on MRP)
ContainsDiazepam(2.0 Mg) + Imipramine(25.0 Mg)
UsesTreatment of Major depressive disorder (MDD)
Side effectsDrowsiness, Headache, Nausea, Vomiting, Feeling sleepy, Diarrhoea or Constipation, Increased sweating
Check more medicines with composition as Diazepam(2.0 Mg) + Imipramine(25.0 Mg)

Uses of Depsonil Dz Tablet

  • As per CDSCO, Depsonil Dz is used for the treatment of Major depressive disorder (MDD)

Contraindications of Depsonil Dz Tablet

  • If you are allergic to any component of the Depsonil Dz, i.e. Imipramine and Diazepam.
  • If you are already taking antidepressants, anti-anxiety or sedative medications.
  • If you are taking narcotic or opioid pain relievers.
  • If you have acute angle glaucoma, which increases the fluid pressure in the eyes.
  • If you are experiencing suicidal thoughts or ideation.
  • If you have respiratory depression, which is a slow and steady decline in breathing.
  • If you have a history of substance abuse.
  • If you have liver and kidney disease.
  • If you are pregnant.
  • If you are a breastfeeding mother.

Side effects of Depsonil Dz Tablet

  • Drowsiness
  • Headache
  • Nausea
  • Vomiting
  • Feeling sleepy
  • Diarrhoea or Constipation
  • Increased sweating

Precautions and Warnings of Depsonil Dz Tablet



Can I take Depsonil Dz during pregnancy?
No. Depsonil Dz is unsafe during pregnancy. Pregnant women should take this medicine only if it is necessary or in some life-threatening condition. Pregnant women are advised to consult a doctor before taking this medicine and Inform their doctor about their pregnancy or intention to conceive at the time of prescription.

Breast Feeding

Can I take Depsonil Dz while breastfeeding?
No, Depsonil Dz is not recommended during breastfeeding. It gets excreted into breast milk and can harm the baby. Your doctor may advise you to discontinue breastfeeding for a while or prescribe low doses if you continue breastfeeding. Discuss the potential risks and benefits of taking this medicine with your doctor.


Can I drive if I have taken Depsonil Dz?
Depsonil Dz may cause side effects that could affect your ability to drive. The tablet may cause decreased alertness, sedation, blurring of vision, mental confusion, nausea, and can cause dizziness, lethargy, lightheadedness. Do not drive if you are experiencing these side effects after taking this medicine.


Can I consume alcohol with the Depsonil Dz?
Alcohol consumption with Depsonil Dz is not advised. It increases the severity of side effects like decreased vision, dizziness, drowsiness, sedation, liver injury, etc. It can also worsen the condition of your disease.

Other General Warnings

Talk to your doctor if
  • You have any allergic reactions after taking Depsonil Dz.
  • You have any self-harming thoughts or suicidal ideation.
  • You have trouble breathing or talking.
  • You experience any severe side effects persistently.
  • Your symptoms do not resolve, or there is a worsening of your condition.
  • You are an elderly patient over 65 years.
  • You have a history of mild or severe liver and kidney disease; this medicine may need a dose adjustment.
  • You have withdrawal symptoms like agitation, nausea, tremor, sweating and confusion.
  • You are pregnant or planning a pregnancy during the course of treatment.
  • You are using oral contraceptives.
  • You are using any ayurvedic or herbal medicines, vitamins, and other health supplements.

Mode of Action of Depsonil Dz Tablet

How Does It Work?

Depsonil Dz is a combination medicine that contains Imipramine-25mg and Diazepam-2mg as an active ingredient. Imipramine is an antidepressant that works by inhibiting the reuptake (reabsorption) of ...
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Directions for Use of Depsonil Dz Tablet

  • Take Depsonil Dz as prescribed by the doctor.
  • You can take this medicine with or without food or as prescribed.
  • Take this medicine on a regular schedule, preferably at the same time every day.
  • Consume the whole tablet with a glass of water. Do not crush/break the tablet or chew this medicine.
  • Do not take this tablet with other medications without consulting your doctor.
  • Don’t stop taking this medication abruptly, as it may lead to withdrawal symptoms.
  • Do not consume if the package has been opened.
  • Don’t exceed the dosage, even if you cannot feel its effects.

Interactions of Depsonil Dz Tablet

Interactions with other medicines

  • Concomitant use of this medication with other CNS depressants and opioids is strictly contraindicated, as it may cause respiratory depression, coma and death.
  • This medicine should not be used concomitantly or within two weeks of using Monoamine oxidase inhibitors (MAOIs) like isocarboxazid, linezolid, methylene blue, Selegiline, Rasagiline, etc. It is poten...
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  • Interaction with an antidepressant, antihistamines (allergy medicines), Pain killers, such as morphine, oxycodone, fentanyl, hydrocodone, tramadol, codeine, sleeping pills, etc., can increase drowsine...
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  • Interaction with antifungal medicines like fluconazole, ketoconazole and itraconazole can reduce the effects of it.
  • Interaction with birth control pills or oral contraceptives can reduce its effectiveness.
  • Interaction with Herbal products like St john’s wort can lead to life-threatening side effects.

Interactions with food items

  • You can continue with the regular diet as food doesn’t influence the effect of Depsonil Dz. However, avoid consuming Tyramine rich foods such as cheese, milk, meat, chocolate, chicken liver etc.

Storage and disposal of Depsonil Dz Tablet

Store Depsonil Dz at room temperature in a cool and dry area, away from sunlight. Keep the medication away from the reach of children and pet animals in a closed or locked cabin. Do not remove the med...
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Dosage of Depsonil Dz Tablet


Depsonil Dz overdose symptoms may include fainting, somnolence, impairment of motor functions – dizziness, poor coordination, muscle weakness, loss of balance, low blood pressure (hypotension), shallo...
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Missed a Dose

If you miss a dose of Depsonil Dz, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it’s recommended to skip the missed dose a...
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Content Details


Dr. Zishan Ahmad

Final year MBBS Student


Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)


Q: How much time does the Depsonil Dz take to show its desired effect?

A: Depsonil Dz usually takes between 4 to 6 weeks before you see improvement in your symptoms. Once you're feeling better, you are advised to continually take this medicine for several more months to prevent the symptoms from returning and follow the doctor's advice properly.

Q: Can I discontinue taking Depsonil Dz on my own after improving my symptoms?

A: No, Do not stop taking Depsonil Dz despite having symptomatic relief. Abrupt stoppage of this medication can cause withdrawal symptoms which can be severe and debilitating. Consult your doctor before stopping the medication as doses need to be slowly tapered to avoid side effects.

Q: Does taking Depsonil Dz affects my sexual life?

A: Depsonil Dz can cause decreased sexual drive, problems getting an erection and ejaculating, difficulty achieving orgasm in women. These side effects usually pass on their own after a couple of weeks. However, if you persistently experience these side effects, consult your doctor.
Product Details
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Last Updated on: 15 Mar 2022 | 09:44 AM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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