Combutol 400mg Strip Of 10 Tablets

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10 Tablet(s) in Strip

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Combutol 400 MG Description

Combutol 400 mg Tablet belongs to the antitubercular group of medicines. The active ingredient in Combutol 400 mg Tablet is ethambutol. This medicine is an antibiotic used as a first-line medicine in

the treatment of tuberculosis along with the combination of other medicines. Tuberculosis affects different organs in our body like lungs in pulmonary tuberculosis, intestine in abdominal tuberculosis, etc. Ethambutol is represented by the letter ‘E’ in the chemotherapy of WHO proposed 6-8 month multi-medicine ‘short course’ regimens in the treatment of tuberculosis by categorising the patients. All the regimens have an initial intensive phase with 4-5 medicines lasting for 2-3 months with a goal of rapidly killing the bacteria. Added to the triple medicine regimen of RHZ (combination of rifampicin, isoniazid, and pyrazinamide), ethambutol has been found to hasten the rate of sputum conversion and to prevent the development of resistance. One of the main purposes of using ethambutol in first-line therapy is to prevent the development of resistance. Disclaimer: If you are experiencing cough along with the sputum for more than 2 weeks, it is better to consult a physician for the evaluation of tuberculosis

Product Summary

Offer Price	₹24.11
You Save	₹3.29 (12% on MRP)
Contains	Ethambutol(400.0 Mg)
Uses	Tuberculosis
Side effects	Eye-related problems, Skin rashes, Nausea (vomiting sensation), Vomitings, Diarrhoea, Pain and swelling of joints, Chills, Tense skin over affected joints, Yellowing of eyes (Jaundice)
Therapy	ANTI-TUBERCULAR

Check more medicines with composition as Ethambutol(400.0 Mg)

Precautions and Warnings

Uses of Combutol 400 MG

Combutol 400 mg Tablet is used in,
Treatment of tuberculosis affecting various organs like pulmonary tuberculosis, tuberculous meningitis (affecting membranes around the brain), abdominal tuberculosis, urogenital tuberculosis (affectin...
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Re-treatment and prophylactic treatment of tuberculosis.

Contraindications of Combutol 400 MG

If you are allergic to ethambutol or any of its excipients
If you have any pre-existing health conditions like optic neuritis (inflammation of nerve fibres behind your eyes)
If you are suffering from serious liver conditions
If you are suffering from serious kidney problems

Side effects of Combutol 400 MG

Decreased vision,
Blurred vision
Optic neuritis (usually observed with higher dosage or overdose).
Skin rashes
Nausea (vomiting sensation)
Vomiting
Diarrhoea
Cardiac problems
Pain and swelling of joints
Chills
Tense skin over affected joints
Yellowing of eyes (Jaundice)

Precautions and Warnings of Combutol 400 MG

Pregnancy

Can I take Combutol 400 mg Tablet during pregnancy?

Combutol 400 mg Tablet belongs to Category C medicine. There is not much evidence regarding its effects on pregnancy, but animal studies showed reproductive toxicity. So, it is advised to inform your doctor about your pregnancy or related future plans so that they can give you the appropriate treatment.

Breast Feeding

Can I take Combutol 400 mg Tablet while breastfeeding?

Combutol 400 mg Tablet or its metabolites may pass into breast milk. However, there is no proper evidence regarding the effect of this medicine on infants or newborns. It is advised to inform your doctor about the medicines you are using before breastfeeding.

Driving

Can I drive if I have taken Combutol 400 mg Tablet?

Combutol Tablet may affect your eyes and may cause sight-related problems. There are more chances of the problem if you have a pre-existing eye-related problem. So, it is firmly advised not to drive vehicles or operate any heavy machinery if you are taking Combutol 400 mg.

Alcohol

Can I consume alcohol with Combutol 400 mg?

There is not much evidence regarding the interaction of alcohol with Combutol Tablet. However, it is not advised to take alcohol while you are taking Combutol 400 mg as it may affect your liver. It should be avoided, especially if you have any pre-existing liver diseases or eye-related problems.

Other General Warnings

Talk to your doctor if

You have a history of liver disease, kidney disease, gout, eye-related problems.
You are pregnant, are planning a pregnancy, or you conceive during the course of medication.
You observe any changes in your vision or any eye-related problems while you are on Combutol 400 mg. It is advised to have regular eye checkups, especially if you have any pre-existing eye-related pro...
Read more
You have had tuberculosis in the past. Inform your doctor about treatment history and medicines used so that appropriate medicines can be prescribed.
You experience side effects that persist or worsen in time.
Do not stop taking Combutol 400 mg abruptly without consulting your physician.

Mode of Action of Combutol 400 MG

How Does It Work?

Ethambutol is the active ingredient of Combutol Tablet. The mechanism of action of ethambutol is not fully understood. But it has been found to inhibit arabinosyltransferase(an enzyme involved in arab...

Directions for Use of Combutol 400 MG

Take Combutol 400 mg Tablet exactly as prescribed by your physician.
Do not exceed the prescribed dosage or miss a dose.
Do not discontinue the medication until the completion of the course or as directed by your physician even if the symptoms disappear.
Take Combutol Tablet as a whole, with a glass of water.
Do not break this medicine or chew it.
For optimal pharmacological effects, it is better to take the tablet at the same time every day.
It is advised to note down the days of consumption of the tablet in a week in order to avoid missing the doses or to avoid overdose.

Interactions of Combutol 400 MG

Interactions with other medicines

Inform your physician about any other medicines or supplements you are taking to avoid side effects associated with medicine interaction.
It is advised to take Combutol 400 mg Tablet 2 hours before you take antacids. Antacids containing Aluminium hydroxide are known to decrease the absorption of Combutol 400 mg. Your doctor may advise a...
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Vitamin supplements may also interact with Combutol 400 mg Tablet. So, it is advised to inform your physician about your treatment history before prescribing the medications.

Interactions with food items

Combutol 400 mg Tablet can be taken with or without food. There is no proper evidence of its interaction with the food. However, if you observe any difficulty while taking Combutol 400 mg Tablet along...
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Storage and disposal of Combutol 400 MG

Combutol Tablet should be stored at room temperature in a dry container. Keep it out of reach of children. Avoid exposing the medicine to heat, sunlight, or moisture. Open the seal only before taking ...

Dosage of Combutol 400 MG

Overdose

Overdose of Combutol Tablet may cause symptoms like vomiting, fever, headache, dizziness, disorientation, etc. Additionally, if you experience any side effects like vision problems, skin-related probl...

Missed a Dose

If you miss a dose of Combutol Tablet, take it as soon as you remember. But if it's almost the time for the next dose, avoid taking the missed dose. Inform your physician about your missed dose. The g...

Content Details

WRITTEN BY

Dr. Paluri Venkata Narasimha Sairam

MBBS

REVIEWED BY

Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)

Q: What happens if I stop taking Combutol 400 mg after my symptoms subside?

A: If you start the short-course regimen, your symptoms may subside by the 2nd month. Usually, many people discontinue taking Combutol Tablet from then onwards. It may be harmful as it may lead to the development of resistant bacteria, and you may land into MDR-TB ( Multidrug-resistant tuberculosis). It is a condition where the bacteria in your body have developed resistance, and you may have to add more medications to your list to control it for extended durations.

Q: What symptoms should I observe if I have a history of liver disease?

A: You should keep an eye on the symptoms like yellowing of skin or eyes, dark urine, stomach upset, etc. Consult your physician immediately if you observe any.

Q: Can I use Combutol in other doses if Combutol 400 mg is not available?

A: No, you should not take Combutol in other doses if Combutol 400 mg is not available. You should bring it to your doctor’s notice.

Q: What symptoms should I observe if I have a history of eye-related problems?

A: Bring it to your doctor’s notice if you observe decreased or blurred vision, Optic neuritis (usually observed with higher dosage or overdosage). Early detection of these problems may help prevent the deterioration of the condition as these changes are reversible by stopping or decreasing the dose of the medicine as advised by your doctor.

References

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Product Details

Brand

COMBUTOL

Country of Origin

India

Expires on or After

30/07/2027

Manufacturer Details

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Last Updated on: 07 Aug 2024 | 08:04 PM (IST)

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एक मुट्ठी बेरीज़ खाएँ, और आपका मुंह मिठास से भर जाएगा। इस वैश्विक महामारी ने हमें बेरीज़ के महत्व से परिचय कराया है चूंकि ये विटामिन C का एक समृद्ध स्रोत हैं आख़िरकार जो हमारी इम्यूनिटी को बढ़ाती है। सभी बेरीज़ में, जामुन (ब्लैकबेरी) एक बहुमुखी बेरी है जिसमें बहुत सारे पोषक तत्व होते हैं।

जीरा (Cumin in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू!

एक स्वस्थ जीवन जीने और वज़न कम करने के लिए हम अलग-अलग तरीकों और स्वास्थ्यवर्धक काढ़ों जैसी चीज़ें आज़माते रहते हैं। अनगिनत स्वास्थ्य लाभों का वादा करने के अलावा, ये शरीर को डिटॉक्स करने और वज़न घटाने में मदद करने का भी दावा करते हैं। लेकिन एक पेय (ड्रिंक) है जो ऐसा करने में कामयाब

मशरूम (Mushroom in Hindi) के उपयोग, फ़ायदे, और न्यूट्रिशनल वैल्यू

परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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