Clozine 100mg Tablet
Clozine 100 MG Description
Clozine tablet is a prescription medicine. It is used for managing symptoms of schizophrenia (a mental disorder) and other psychotic disorders. Managing the symptoms of mania in bipolar disorder, ner
vousness, anxiety, behaviour problems, etc., are other uses of Clozine tablets. Clozine Tablet has a single active ingredient, chlorpromazine. It belongs to the class of antipsychotic medications. The mode of action of Clozine tablets is to block certain receptors in the nervous system, which improves behaviour and mood. Psychotic conditions make it difficult for the affected person to discern between reality and imagination. This medication helps in managing such symptoms and improves the quality of life. The doctor’s directions for Clozine tablets should be strictly followed; otherwise, there may be side effects. Clozine tablets can be taken with or without food. Most side effects of Clozine tablets do not require any medical intervention as they subside gradually. However, it is best to consult with a doctor in case of persistent side effects. Abruptly stopping this medicine can cause withdrawal symptoms such as sweating, nervousness, vomiting, and dizziness.
|Uses||Schizophrenia, Psychotic Conditions, Bipolar Mania, Nausea And Vomiting, Anxiety, Hiccups, Behavioural Problems like Aggressiveness|
|Side effects||Nausea, Weight gain, Constipation, Sedation, Orthostatic hypotension, Dry mouth|
Uses of Clozine 100 MG
- As per USFDA, the Clozine tablet is used for the following:
- Treatment of symptoms associated with schizophrenia, as an antipsychotic medicine (reduces strong and inappropriate symptoms, disturbed/unusual thinking, etc.)
- Treatment of severe behaviour problems such as explosive, aggressive behaviour and hyperactivity in children from the age 1 to 12
- Treatment of symptoms associated with psychotic disorders
- Management of mania in bipolar disorder
- Treatment of nausea and vomiting (for example, before surgery)
- Treatment of intractable hiccups
- Treatment of acute intermittent porphyria (condition in which certain natural substances build up in the body, causing stomach pain, thinking and behaviour changes, and other symptoms)
Contraindications of Clozine 100 MG
- If you've an allergy to any of the ingredients of Clozine Tablet.
- If you are diagnosed with Reye’s Syndrome.
- If you have Neuroleptic Malignant Syndrome (NMS).
- If you've severe central nervous system depression (reduces central nervous system functionality of breathing).
- If you've narrow-angle glaucoma (increased pressure in the eye).
- If you're suffering from tardive dyskinesia (involuntary movements of the face).
- If you have dementia (memory loss); this medicine can increase the side effects and even cause death.
- If you have a urinary problem.
- If you are pregnant.
- If you are breastfeeding.
- If you are a child or adolescent under 18.
- If the affected person is in a comatose state.
Side effects of Clozine 100 MG
- Weight gain
- Dry mouth
- Blurred vision
- Urinary retention
- Orthostatic hypotension (sudden fall of blood pressure on standing)
- Decreased sexual ability
Precautions and Warnings of Clozine 100 MG
Other General Warnings
- You've hypertension or high blood pressure.
- You've seizure syndrome. Clozine tablet should be used with extreme caution, as it can increase the risk of seizures.
- You've heart, lung or kidney disorder.
- You've a planned surgery or need to be anaesthetised.
- You are an older adult. Due to slow metabolism in older adults, this medicine takes time to be eliminated from the body.
- You've stayed in sunlight for a long time, been exposed to insecticides, or been administered atropine.
- You use any herbal or Ayurvedic medicines and supplements.
- Do not suddenly stop using the Clozine tablets, as this can cause neuroleptic malignant syndrome (fever, altered mental status, muscle stiffness, etc.).
Mode of Action of Clozine 100 MG
How Does It Work?
Directions for Use of Clozine 100 MG
- Take Clozine tablets in the recommended dose and duration.
- You can take Clozine tablets with or without food. In case of stomach problems, take the pills after meals.
- Do not take more than a tablet at one time without informing the doctor, as this can lead to an overdose.
- Take a Clozine tablet immediately after opening its pack.
- Swallow the tablet as a whole with a glass of water; do not break or chew it.
- Try to take Clozine tablets at the same time every day for optimal pharmacological effects.
- Check the expiration date on the packaging before using the medicine.
Interactions of Clozine 100 MG
Interactions with other medicines
- Notify your doctor about all medicines and supplements you are currently taking to avoid side effects associated with medicine interaction.
- Do not take a Clozine tablet if you use medication that increases blood pressure. This tablet can further increase blood pressure.
- Clozine medicine lowers the effect of blood thinners like warfarin.
- Using certain medicines like phenytoin and propranolol can increase the amounts of both medicines in the body.
- Using this medicine with opioid or narcotic pain relievers can increase side effects like drowsiness.
- If you use medicines that lower lung secretions or saliva, Clozine tablets will negate the effects of those medicines.
- Do not use other antipsychotics, anticonvulsants, and anti-Parkinsonian medications with Clozine tablets. It can cause adverse reactions.
- Other medicines that Clozine tablets interact with are antihistamines (allergy medicine), heart medicines, and fever-reducing medicines.
Interactions with food items
- Try to avoid grapefruit and its juice, as this fruit can increase the levels of Clozine tablet in the body. It can lead to many side effects.
Storage and disposal of Clozine 100 MG
Dosage of Clozine 100 MG
Missed a Dose
Frequently Asked Questions (FAQs)
Q: Can Clozine tablets cause heatstroke?
Q: Will I gain weight by using Clozine tablets daily?
Q: Can I stop taking Clozine tablets if I start feeling better?
- Chlorpromazine: MedlinePlus Drug Information [Internet]. medlineplus.gov. U.S. National Library of Medicine [cited 21 Mar 2022]. Available from:
- New Drugs Approved by CDSCO [Internet]. cdscoonline.gov.in. 2022 [cited 21 Mar 2022]. Available from:
- Chlorpromazine [Internet]. Drugs and Lactation Database (LactMed) [Internet]. U.S. National Library of Medicine; 2021 [cited 21 Mar 2022]. Available from: