Clozine 100mg Tablet

• As per USFDA, the Clozine tablet is used for the following:
• Treatment of symptoms associated with schizophrenia, as an antipsychotic medicine (reduces strong and inappropriate symptoms, disturbed/unusual thinking, etc.)
• Treatment of severe behaviour problems such as explosive, aggressive behaviour and hyperactivity in children from the age 1 to 12
• Treatment of symptoms associated with psychotic disorders
• Management of mania in bipolar disorder
• Treatment of nausea and vomiting (for example, before surgery)
• Treatment of intractable hiccups
• Treatment of acute intermittent porphyria (condition in which certain natural substances build up in the body, causing stomach pain, thinking and behaviour changes, and other symptoms)

• If you've an allergy to any of the ingredients of Clozine Tablet.
• If you are diagnosed with Reye’s Syndrome.
• If you have Neuroleptic Malignant Syndrome (NMS).
• If you've severe central nervous system depression (reduces central nervous system functionality of breathing).
• If you've narrow-angle glaucoma (increased pressure in the eye).
• If you're suffering from tardive dyskinesia (involuntary movements of the face).
• If you have dementia (memory loss); this medicine can increase the side effects and even cause death.
• If you have a urinary problem.
• If you are pregnant.
• If you are breastfeeding.
• If you are a child or adolescent under 18.
• If the affected person is in a comatose state.

• Dizziness
• Weight gain
• Dry mouth
• Blurred vision
• Urinary retention
• Orthostatic hypotension (sudden fall of blood pressure on standing)
• Decreased sexual ability

Other General Warnings

• You've hypertension or high blood pressure.
• You've seizure syndrome. Clozine tablet should be used with extreme caution, as it can increase the risk of seizures.
• You've heart, lung or kidney disorder.
• You've a planned surgery or need to be anaesthetised.
• You are an older adult. Due to slow metabolism in older adults, this medicine takes time to be eliminated from the body.
• You've stayed in sunlight for a long time, been exposed to insecticides, or been administered atropine.
• You use any herbal or Ayurvedic medicines and supplements.
• Do not suddenly stop using the Clozine tablets, as this can cause neuroleptic malignant syndrome (fever, altered mental status, muscle stiffness, etc.).

• Take Clozine tablets in the recommended dose and duration.
• You can take Clozine tablets with or without food. In case of stomach problems, take the pills after meals.
• Do not take more than a tablet at one time without informing the doctor, as this can lead to an overdose.
• Take a Clozine tablet immediately after opening its pack.
• Swallow the tablet as a whole with a glass of water; do not break or chew it.
• Try to take Clozine tablets at the same time every day for optimal pharmacological effects.
• Check the expiration date on the packaging before using the medicine.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines

• Notify your doctor about all medicines and supplements you are currently taking to avoid side effects associated with medicine interaction.
• Do not take a Clozine tablet if you use medication that increases blood pressure. This tablet can further increase blood pressure.
• Clozine medicine lowers the effect of blood thinners like warfarin.
• Using certain medicines like phenytoin and propranolol can increase the amounts of both medicines in the body.
• Using this medicine with opioid or narcotic pain relievers can increase side effects like drowsiness.
• If you use medicines that lower lung secretions or saliva, Clozine tablets will negate the effects of those medicines.
• Do not use other antipsychotics, anticonvulsants, and anti-Parkinsonian medications with Clozine tablets. It can cause adverse reactions.
• Other medicines that Clozine tablets interact with are antihistamines (allergy medicine), heart medicines, and fever-reducing medicines.

Interactions with food items

• Try to avoid grapefruit and its juice, as this fruit can increase the levels of Clozine tablet in the body. It can lead to many side effects.