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Molecule Description

Tizanidine is a short-acting muscle relaxer. It is used to treat spasticity by temporarily relaxing the muscle tone.

Uses of Tizanidine

Treat spasticity by temporarily relaxing the muscle tone.

Contraindications of Tizanidine

When should one not use Tizanidine

  • Slow heartbeat
  • Abnormally low blood pressure
  • Severe liver disease
  • Kidney disease
  • Mental disorder with loss of personality and reality
  • An allergy to the medicine and any of its components

Side effects of Tizanidine

Common side effects of this drug are:

  • Dizziness
  • Lightheadedness
  • Drowsiness
  • Dry mouth
  • Fatigue
  • Sleepiness
  • Weakness
  • Blurred vision
  • Constipation
  • Urinary frequency
  • Vomiting

Precautions and Warnings of Tizanidine


Can I take Tizanidine during pregnancy?
Not recommended in pregnancy. Use this medicine only when clearly indicated by your doctor.

Breast Feeding

Can I take Tizanidine while breastfeeding?
Maybe excreted in breast milk due to lipophilic nature, so avoid using this medicine while breastfeeding.


Can I drive if I have consumed Tizanidine?
This medicine may lead to cause dizziness or drowsiness. Do not drive unless you feel well.


Can I consume alcohol with Tizanidine?
You may experience dizziness or drowsiness if you consume alcohol with this medicine, thus avoid drinking alcohol.

Other General Warnings

Talk to your doctor if
You are taking other medicines/ herbal medicines.

Mode of Action of Tizanidine

How Does It Work?

This medicine shows action by working on the Alpha-2 adrenergic receptor present in the brain and spinal cord, which leads to a reduction in the release of excitatory amino acids like glutamate and aspartate, and reduces the neuronal firing. Thereby gives relief to muscle stiffness or spasm, which ultimately improves pain and movement of muscles.
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Interactions of Tizanidine

Interactions with other medicines

  • Fluvoxamine
  • Benazepril
  • Atenolol
  • Ciprofloxacin
  • Amlodipine
  • Amiodarone
  • Citalopram
  • Clozapine

Dosage of Tizanidine


Inform your doctor immediately in case of overdose. If you have symptoms of decreased blood pressure, severe dizziness, blurring of vision or vomiting, immediately seek medical consultation for further evaluation.
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Missed a Dose

Take the missed dose as early as you remember. If the time for the next dose is closer, skip the missed dose. Do not take extra medicine to compensate for the missed dose.

Content Details


Dr. Abhishek B L

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare provider before taking this medicine?

A: Discuss all your health conditions. Do not use this medicine if you are allergic to it and if you are taking certain antidepressants or antibiotics. Do not use this medicine without telling your doctor, especially if you are pregnant or breastfeeding a baby.

Q: How to store this medicine?

A: Store this medicine at room temperature in a closed container away from moisture and heat. Keep out of reach of kids and far away from pets.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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