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Diclofenac+Metaxalone

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Molecule Summary

Uses
Muscle spasm, muscle pain
Therapy
Muscle Relaxant, Analgesic
Side Effects
Headache, dizziness, nausea, vomiting, stomach upset
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Molecule Description

Diclofenac+Metaxalone is a combination medication used to relieve muscle pain and discomfort caused by injuries or sprains. It contains diclofenac, an NSAID that reduces inflammation and pain, and metaxalone, a muscle relaxant. This combination helps to alleviate pain and discomfort by reducing inflammation and relaxing the affected muscles. Diclofenac+Metaxalone may cause side effects such as headache, nausea, vomiting, and dizziness. While these side effects are usually temporary, consult your doctor immediately if they persist or worsen. Diclofenac+Metaxalone should be taken exactly as prescribed by your doctor, preferably with food to minimise stomach upset. Before starting Diclofenac+Metaxalone, inform your doctor about all existing medical conditions, including pregnancy, breastfeeding, or any plans to become pregnant.

Uses

Diclofenac+Metaxalone is used for the treatment of pain due to muscle spasm. It relieves pain, swelling and discomfort of muscle and improves muscle movement and activity.

Contraindications

When should one not use Diclofenac+Metaxalone

  • If you are allergic to diclofenac and metaxalone or any other ingredients of Diclofenac+Metaxalone.
  • If you are suffering from acidity problems, have a history of recurrent peptic ulcer or bleeding disorder
  • If you have a history of stomach or intestine bleeding or perforation, relating to the previous use of pain killer (NSAIDs) medicines or if you have any liver or kidney problems.
  • If you have heart problems like congestive heart failure (decreased pumping of the heart), ischemic heart disease (heart attack due to blood supply disturbance), peripheral arterial disease (a condition in which there is reduced blood flow to limbs), cerebrovascular disease (a problem in blood flow in the brain), stroke, heart attack or any other heart issues.
  • If you have a history of attacks of asthma, angioedema (swelling of face, skin and tongue breathing problem), urticaria (skin redness and itching) or acute rhinitis (runny nose, sneezing, etc.)
  • If you have a history of decreased blood count due to any medicines in the past
  • If you have anaemia or have problems with your blood circulation
  • If you are pregnant or are breast-feeding
  • If you are taking aspirin or other NSAID painkillers

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Nervousness
  • Irritability

Precautions and Warnings

Pregnancy

Pregnancy

Consulting a doctor before taking Diclofenac+Metaxalone during pregnancy is recommended. They can assess the potential risks and benefits for both the mother and the baby.

Breast Feeding

Breast Feeding

Diclofenac+Metaxalone passes into human milk. Hence, this medicine is not recommended during breastfeeding. You should consult your doctor before using this medicine during breastfeeding.

Driving

Driving

You may experience visual disturbances, inability to recognise objects properly, sleepiness and dizziness while on treatment with Diclofenac+Metaxalone. Therefore, you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Alcohol

If you take Diclofenac+Metaxalone along with alcohol, it may make you feel drowsier and dizzier, so your ability to concentrate decreases. Hence, it is advisable to not consume alcohol along with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are experiencing high blood pressure, increased heartbeats, increased body temperature, sweating, agitation and irritation
  • You are above 65 years, as it should be used cautiously in elderly patients
  • You have blood clotting, liver, kidney and heart problems
  • You have asthma, diabetes, high blood pressure or cholesterol
  • You are pregnant or an active smoker
  • You had or may have a surgery
  • You are having diseases like Systemic Lupus Erythematosus or mixed connective tissue disease
  • You are taking water pills or painkillers
  • You are going for a lab test, as this medicine may interfere with the lab tests, inform the concerned person.
  • This medicine should not be used in children below 12 years of age.
  • Diclofenac+Metaxalone may impair female fertility and is not recommended in women who want to conceive or are of childbearing age.

Mode of Action

How Does It Work?

Diclofenac+Metaxalone is a medication that contains a combination of two active ingredients, diclofenac and Metaxalone, to alleviate muscle pain. The medicine works by relaxing the muscles through its action on the central nervous system. It also helps to lower the levels of chemical substances that cause pain and inflammation in the body.

Interactions

Interactions with other medicines

  • Diclofenac+Metaxalone can interact with several other medications, potentially increasing the risk of side effects or reducing their effectiveness.
  • Serious Interactions: Combining Diclofenac+Metaxalone with certain medications like fentanyl, methadone, and triptans can significantly increase blood pressure, heart rate, and body temperature, potentially leading to a medical emergency.
  • Blood Pressure Medications: Using Diclofenac+Metaxalone with certain blood pressure medications, such as atenolol, propranolol, captopril, and lisinopril, may decrease their blood pressure-lowering effects.
  • Immunosuppressants: Combining Diclofenac+Metaxalone with medications like cyclosporine and tacrolimus can increase the risk of muscle weakness and irregular heartbeats.
  • Blood Thinners: Combining Diclofenac+Metaxalone with blood thinners like warfarin and heparin can increase the risk of bleeding.
  • Other Medications: Diclofenac+Metaxalone may also interact with other medications, including psychiatric medications, painkillers, cholesterol-lowering medications, antibiotics, and medications used for heart conditions, seizures, fungal infections, and HIV.

Interactions with food items

Diclofenac+Metaxalone can be taken with or without food. However, it is best to take it with food or just after a meal to avoid stomach upset.

Dosage

Overdose

  • If you have taken more Diclofenac+Metaxalone you may get symptoms like headache, nausea, vomiting, pain below the ribs and above the stomach, and occasionally fits.
  • If you experience any of the symptoms or think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Diclofenac+Metaxalone, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

It is known that Diclofenac+Metaxalone may damage the liver and reduce its function, so if you are already having any liver problem, it is advisable to avoid this medicine or consult your doctor about it.

Diclofenac+Metaxalone content may interfere with the bleeding tendency in the patient. Hence, it should be avoided during or immediately after the surgery as per the advice from your doctor.

The most common side effects of taking Diclofenac+Metaxalone are nausea, vomiting, upset stomach, drowsiness, headache and nervousness. If any of these symptoms worsen, consult your doctor.

No, Diclofenac+Metaxalone is not a steroid medicine. It is a painkiller medicine used to provide relief from muscular pain.

If Diclofenac+Metaxalone is used to provide relief from short term pain, it can be discontinued once your pain is relieved. However, Diclofenac+Metaxalone should be continued if your doctor has advised you to do so.

You can take Diclofenac+Metaxalone but only after the doctor's advice and for a specific duration. Do not exceed the maximum daily doses and treatment durations recommended. If you do not feel any improvement, inform the doctor. But do not take it endlessly on your own without consulting a doctor.

Diclofenac+Metaxalone should be taken as directed by your doctor. However, it would be best if you take it after your meal to avoid stomach discomfort.

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