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Molecule Description

Ceftriaxone is an antibiotic that fights bacterial infections.

Uses of Ceftriaxone

  • Lower respiratory tract infections- pneumonia
  • Skin infections
  • Ear infections
  • Urinary tract infections
  • Bone and joint infections
  • Meningitis
  • Gonorrhea
  • Infection of the stomach and intestine
  • Before surgery to prevent infections

Contraindications of Ceftriaxone

When should one not use Ceftriaxone

  • If you are allergic to Ceftriaxone, Cefuroxime, Cefprozil, Cefdinir, Penicillin or other antibiotics
  • It should not be given to premature babies

Side effects of Ceftriaxone

Common side effects of this drug are:

  • Blood cell disorder- decrease in white blood cells or platelets
  • Diarrhea
  • Rash
  • Allergic reaction like- fever, chills, rash, hives, breathing difficulty, swelling over your face, lips and throat
  • Dark urine, pale or yellow skin
  • Headache, dizziness
  • Pain at the injection site

Precautions and Warnings of Ceftriaxone


Can I take Ceftriaxone during pregnancy?
This medicine is probably safe and can be used in pregnancy only if prescribed by your physician.

Breast Feeding

Can I take Ceftriaxone while breastfeeding?
This medicine passes into human milk in low quantities. It is probably safe to breastfeed but observe for symptoms of diarrhea in the baby.


Can I drive if I have consumed Ceftriaxone?
This medicine can cause side effects like confusion, feeling less alert or dizziness. If you experience any of these, don’t drive.


Can I consume alcohol with Ceftriaxone?
No known interaction.

Other General Warnings

Talk to your doctor if
  • If you have liver or kidney problems or stones in your gall bladder or kidney
  • Complete the course of the antibiotic even if you are feeling better after a few doses
  • Not completing the course of antibiotic can lead to resistance
  • If you get persistent diarrhea, immediately inform your doctor
  • Never use Ceftriaxone in a premature baby or a newborn baby who has jaundice. The injection can be dangerous in a newborn baby when given along with medicines that contain calcium

Mode of Action of Ceftriaxone

How Does It Work?

Ceftriaxone is an antibiotic (Cephalosporins). It fights a wide range of bacterial infections by killing the bacteria.

Interactions of Ceftriaxone

Interactions with other medicines

Interaction of Ceftriaxone with other medicines like Aminoglycosides, Chloramphenicol, blood thinners (e.g., Warfarin) over the counter medicines, vitamins and herbal products.

Interactions with food items

No interactions with food have been reported.

Dosage of Ceftriaxone


In the case of overdose nausea, vomiting, diarrhea can occur. Seek emergency medical attention immediately if you overdose.

Missed a Dose

Avoid skipping doses, as this may increase your risk of developing an infection that may be resistant to antibiotics. Take the missed dose as soon as you remember. If the missed dose falls at the time of your next scheduled dose, then skip it. Do not take an extra dose to compensate for it.
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Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare expert before taking Ceftriaxone?

A: You must inform your doctor if you are suffering from any heart, kidney, liver diseases, stomach or intestinal problems like colitis, gall bladder disease or diabetes. Also mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before you start this medication; especially blood thinners or medicines to which you have allergy.

Q: What should I avoid while taking Ceftriaxone?

A: Do not take any medicine if you develop watery or bloody diarrhea while taking Ceftriaxone. Stop the medicine and inform your doctor immediately.
A: When and how to consume the medicine?

Q: You must take medicine precisely the way it is prescribed by the physician. Follow the instructions mentioned on the prescription label. Do not alter the dose unless recommended by your doctor. Do not take it longer or shorter than advised. Skipping doses might make you prone to infections resistant to antibiotics. If you are advised it in injection form, you will be instructed how to inject it into your muscle or vein. You might need to use a liquid diluent to mix the powder before injecting it. Use the diluent that is recommended by your doctor. After diluting it, use the medicine within a stipulated number of hours or days, depending on the instructions. Use disposable needles and syringes. Do not share them with anyone else and dispose of the used needles and syringes as per the state law. If you are using other injectable medicines, flush the intravenous catheter well in between two injections.

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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