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Carbimazole

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Molecule Summary

Uses
Hyperthyroidism
Therapy
Drugs For Hyperthyroidism
Side Effects
Headache, Nausea, Rash
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Molecule Description

Carbimazole belongs to an assortment of medicines called anti-thyroid.

Uses

It is used to treat hyperactive thyroid gland in adults and children.

Contraindications

When should one not use Carbimazole

  • Allergy to Carbimazole
  • Allergy to thyroid medicines like Propylthiouracil
  • If you have severe liver disease or blood disorder

Side effects

Common side effects of this drug are:

  • Allergic reaction like- fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat, running or stuffy nose, sneezing
  • Some infections may occur while you are on this medicine
  • Bleeding from unusual parts
  • Headache
  • Feeling dizziness
  • Joint pain (polyarthritis)
  • Muscle pain
  • Stomach upset
  • Change of taste in mouth
  • Thinning of hair
  • Skin rash
  • Itching
  • Neutropenia (low neutrophil count)
  • Leucopenia (low white blood cell count)
  • Agranulocytosis
  • Nerve pain
  • Liver problems- nausea, vomiting, upper stomach pain, yellowing of skin or eyes, skin itching, loss of appetite, clay-colored stools, dark urine, etc.

Precautions and Warnings

Pregnancy

Pregnancy

You should avoid Carbimazole if you are pregnant or planning pregnancy or breastfeeding. Carbimazole may cross the placenta and harm the unborn baby.

Breast Feeding

Breast Feeding

This medicine can pass into the breast milk and can harm the child Do not breastfeed if you are on a medication of Carbimazole

Driving

Driving

Avoid driving or hazardous activities while on this medicine, as it may cause extreme drowsiness.

Alcohol

Alcohol

No interactions with alcohol has been reported.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are lactose intolerant or have any other lactose deficiency
  • You are receiving radio-iodine (for thyroid problems)
  • You have mild or moderate liver problems, swelling on neck
  • You have bone marrow depression
  • You have a severe blood disorder

Mode of Action

How Does It Work?

Carbimazole is chemically a Thioamide. It helps in decreasing the production of a hormone produced by the thyroid gland known as Thyroxine. Carbimazole blocks the synthesis of Thyroxine (T4) and Triiodothyronine (T3).

Interactions

Interactions with other medicines

  • Blood thinners (e.g., Warfarin)
  • Steroid medicine- Prednisolone
  • Theophylline
  • Erythromycin antibiotic
  • Heart failure medicines like Digoxin, Digitalis
  • High blood pressure medicines like beta-blockers - Propranolol, Atenolol, etc

Interactions with food items

No interactions with food have been in report. Similarly, there have not been any specific reports for adverse interactions with alcohol or tobacco.

Dosage

Overdose

Overdose symptoms may include nausea, vomiting and headache. In the case of an overdose, seek emergency medical attention.

Missed a Dose

Take medicine as soon as you remember. If the missed dose falls at the time of your next scheduled dose, then skip it. Do not take an extra dose to compensate for it.

Frequently Asked Questions (FAQs)

You must inform your doctor if:You are suffering from any blood or liver diseases or goitreAllergic to Carbimazole or any antithyroid medicine like PropylthiouracilHave lactose deficiency or galalactose intolerance or malabsorptionDiscuss the risk involved if you fall into the elderly age category or if you are scheduled for any surgery. Inform your doctor if you are taking any other medicines, supplements, or herbs

You must take the medicine precisely the way it is prescribed by the physicianFollow the instructions mentioned on the prescription labelDo not alter the dose unless recommended by your doctor. Do not take it longer than advisedTake medicine orally. Swallow it with a glass of water with or without food at the same time dailyDo not stop the medication unless advised by your doctor even if you feel better

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