Agomelatine

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Molecule Description

Agomelatine is very much useful in the treatment of depression.

Uses

It is used for the treatment of depression

Contraindications

When should one not use Agomelatine

Allergic to this medicine or Fluvoxamine
Along with the antibiotic, Ciprofloxacin
Liver impairment

Side effects

Common side effects of this drug are:

Nausea
Headache
Dizziness
Fatigue
Anxiety
Back Pain
Excessive sleepiness or sleeplessness
Diarrhea or constipation

Precautions and Warnings

Pregnancy

It is probably unsafe to use this medicine during pregnancy due to the limited information available for the use of this medicine in pregnant women.

Breast Feeding

There is limited information available for the use of this medicine while breastfeeding. Hence it is better to avoid.

Driving

Caution is advised, as taking this medicine may lead to dizziness or sleepiness.

Alcohol

Do not drink alcohol when taking this medicine. It may make you more tired, dizzy, and sleepy than usual.

Other General Warnings

Talk to your doctor if

In case if you are suffering from symptoms that interfere with daily functioning (dementia), your doctor will make an individual evaluation of whether it is right for you to take Agomelatine
Diabetes
Liver disease or any drugs affecting liver function
Any other psychiatric disorder
You have high-risk factors including under-active thyroid or excessive use of alcohol or if you are smoking more than 15 cigarettes/day.
You should inform your doctor before surgery regarding all the products you use (including prescription medicines, non-prescription medicines, and herbal products)
Discuss with your doctor if you have an intolerance to some sugars. This drug may contain lactose.

Mode of Action

How Does It Work?

It works by normalizing the sleep-wake cycle, which is usually disturbed in depression.

Interactions

Interactions with other medicines

This medicine may interact with other drugs used for the treatment of depression, like Fluvoxamine
Antibiotics like Ciprofloxacin, Enoxacin
Medication for the treatment of blood pressure like Propranolol

Interactions with food items

There has not been any report for interaction with food.

Dietary Restrictions

No information is available on interactions of Agomelatine when taken with food, consult your doctor or pharmacist for further details.

Dosage

Overdose

The effects of an overdose may be lethal and need immediate medical attention. The symptoms of overdose can be – nausea, vomiting, dizziness, fatigue, anxiety, extreme sleepiness, etc. If you take an overdose of the medicine, kindly seek emergency medical care immediately.

Missed a Dose

Take the missed dose as early as you remember. If it is very close to the time of next dose, do not take extra medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Inform the doctor about your detailed medical and surgical historyInform your physician if you have any of the following conditions - Any other psychiatric disorders such as mania, hypomania, or bipolar disorder (characterized by experiencing periods of abnormally high excitability and emotions), diabetes, liver disease, suicidal thoughts

Take this medicine exactly as your physician has prescribed.

Be vigilant about signs and symptoms that your liver may not be working correctly. If you observe any of the mentioned signs and symptoms of liver problems: unusual darkening of the urine, light-colored stools, yellow skin/eyes, pain in the upper right belly, unusual fatigue (primarily associated with other symptoms listed above); seek urgent advice from a doctor who may advise you to stop taking Agomelatine.

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