Aldigesic SP Tablet
10 Tablet(s) in Strip
Product Summary
Aldigesic Sp Tablet contains serratiopeptidase 10 mg, aceclofenac 100 mg and paracetamol 325 mg, and is used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and pain and inflammation after surgery. Alkem Laboratories makes this combination; aceclofenac and paracetamol reduce prostaglandin-related pain and inflammation, while serratiopeptidase reduces swelling.
Medically Reviewed by Dr. Avinav Gupta
Last updated on: 21 October 2026 | 11:23 AM (IST)
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| Therapy | Anti-inflammatory, analgesic/antipyretic |
| Composition | Serratiopeptidase(10.0 Mg)+Aceclofenac(100.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) Serratiopeptidase 10.0 Mg+Aceclofenac 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg |
Serratiopeptidase 10.0 Mg+Aceclofenac 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg
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*Offer applicable on orders above ₹1000About Aldigesic
Aldigesic SP tablet is a combination medicine used for short-term relief of acute pain, swelling and inflammation. It contains aceclofenac, paracetamol, and serratiopeptidase.
Aceclofenac is a non-steroidal anti-inflammatory medicine, or NSAID. Paracetamol relieves pain and reduces fever. Serratiopeptidase is an enzyme that helps reduce swelling. Together, these may be prescribed for painful muscle and joint conditions, including muscle spasm, and pain and swelling after a procedure.
Take it exactly as prescribed, at the lowest dose that controls your pain and for the shortest time needed.NSAIDs carry greater risks with higher doses and longer use, so do not continue this medicine on your own.
The most common side effects are nausea, indigestion, stomach pain, dizziness and bowel upset. Taking it with or just after food may help reduce stomach discomfort. Tell your doctor if these persist.
Tell your doctor before starting if you have had a stomach ulcer or bleeding, asthma, heart disease, high blood pressure, kidney or liver problems, or a reaction to aspirin or another anti-inflammatory medicine, and if you are pregnant, planning a pregnancy, or breastfeeding.
Uses
- For the short-term relief of acute painful conditions in adults.
- For acute painful musculoskeletal conditions associated with muscle spasm.
- For the relief of pain and swelling following surgery or injury.
Contraindications
- If you are allergic to aceclofenac, paracetamol, serratiopeptidase or any other ingredient of this tablet.
- If aspirin or another anti-inflammatory medicine has ever caused asthma, wheezing, a skin rash, swelling, or a runny nose.
- If you have an active stomach or intestinal ulcer, bleeding or perforation, or a history of recurrent ulcers or bleeding associated with NSAID use.
- If you have heart failure, established heart disease, or blood pressure that is not controlled.
- If you have severe kidney or liver disease.
- If you are in the last three months of pregnancy.
Side effects
- Nausea or vomiting
- Indigestion, heartburn or stomach pain
- Diarrhoea or constipation
- Dizziness
- Loss of appetite
- Black, tarry stools, or vomiting blood or material that looks like coffee grounds, which may signal bleeding in the stomach
- Yellowing of the skin or the whites of the eyes, dark urine, or pain over the stomach, which may signal liver injury
- Chest pain, breathlessness, weakness on one side, or difficulty speaking
- A spreading rash, blistering or peeling of the skin, or swelling of the face, lips or throat
- Passing much less urine than usual, or swelling of the ankles
Precautions and Warnings
Alcohol
UNSAFEAvoid alcohol while taking Aldigesic SP tablet. Alcohol may increase the risk of stomach bleeding and liver injury, particularly with excessive alcohol intake or other liver risk factors.
Pregnancy
UNSAFEAldigesic SP tablet is not recommended during pregnancy, and using it in the last three months can affect the baby's circulation and the mother's labour. Tell your doctor if you are pregnant, think you may be, or are planning a pregnancy.
Breastfeeding
UNSAFETell your doctor if you are breastfeeding. There is limited safety information for this combination in breastfeeding, so your doctor will advise whether it is suitable or whether another painkiller is a better choice.
Driving
UNSAFEIt can cause dizziness in some people. Do not drive or use machinery until you know how it affects you.
Other General Warnings
- You have kidney or liver problems.
- You have a heart condition, including heart failure or high blood pressure. Anti-inflammatory medicines can raise blood pressure and the risk of heart attack and stroke, particularly at higher doses and with longer use.
- You are older and take a diuretic, or have a kidney disorder, as the risk of kidney failure rises. Your doctor may order kidney function tests.
- You have, or have had, bleeding or ulcers in the stomach or intestine, Crohn's disease or ulcerative colitis, or you notice black, tarry stools.
- You have asthma, as this medicine can make it worse.
- You have systemic lupus erythematosus.
- You drink heavily or have had a problem with alcohol, as the combination with this medicine can damage the liver.
- You have a blood disorder, a clotting problem or anaemia.
- You develop a skin rash or any skin lesion after taking it. Stop the medicine and tell your doctor.
- You are taking another painkiller, a blood thinner, a steroid, lithium, methotrexate or a medicine for blood pressure.
- You are taking any other medicine containing paracetamol.
- Do not use this medicine for longer than the prescribed course. If prolonged treatment is necessary, your doctor may recommend blood counts and liver and kidney function tests.
Liver
WITH CAUTIONTell your doctor if you suffer from a liver disease. It should be avoided in severe liver disease, and both paracetamol and aceclofenac can affect the liver. Your doctor may check your liver function.
Kidney
WITH CAUTIONTell your doctor if you have a kidney disease. Anti-inflammatory medicines can reduce kidney function, so they require medical supervision and should not be used in severe kidney disease unless a specialist specifically advises them.
Children
UNSAFENo. This tablet is for adults. A doctor should decide what is suitable for a child.
Heart
WITH CAUTIONTell your doctor if you have any heart condition. Anti-inflammatory medicines can raise blood pressure and increase the risk of heart problems, so avoid them if you have heart failure or uncontrolled blood pressure.
Geriatrics
WITH CAUTIONElderly patients should take Aldigesic SP tablet only after medical advice. Older adults face a higher risk of stomach bleeding and kidney problems, so the shortest course at the lowest dose is used.
Allergy
CONTRAINDICATEDDo not take it if aspirin or another anti-inflammatory medicine has caused asthma, rash or swelling. Seek help immediately if you have swelling of the face or throat, difficulty breathing, or blistering skin.
Directions for use
- Take Aldigesic SP tablet exactly as your doctor has prescribed.
- Swallow the tablet whole with a glass of water. Do not crush or chew it.
- Take it with or just after food to reduce stomach upset.
- Use it only as long as it controls your pain. Do not continue it on your own after your doctor's prescribed course has finished.
- Do not take any other paracetamol-containing medicine, or another anti-inflammatory painkiller, at the same time.
Storage and disposal
- Store Aldigesic SP tablet in a cool, dry place, protected from moisture, heat and direct light.
- Keep it in the original strip until you take it.
- Keep it out of the sight and reach of children and pets.
- Do not use it after the expiry date printed on the pack.
Quick tips
- This tablet is for short-term relief of pain and swelling. Use it for the condition and the period your doctor specified, at the lowest dose that works.
- Do not take any other medicine containing paracetamol, including cold and flu remedies, while taking it. Too much paracetamol can seriously damage the liver.
- Take it with or after food to reduce stomach upset and nausea.
- Do not take another anti-inflammatory painkiller alongside it, as the risk of stomach ulcers and bleeding rises sharply.
- Avoid alcohol, which adds to the risk of both stomach bleeding and liver damage.
- Stop and seek medical help if you notice black, tarry stools, vomit that looks like coffee grounds, or yellowing of the skin or eyes.
- Dizziness can occur. Do not drive or use machinery until you know how it affects you.
- Tell your doctor about all your medicines and your medical history before you start, particularly any stomach, heart, kidney or liver problem.
- Tell your doctor if you drink heavily or have had a problem with alcohol.
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References
- National Health Service (NHS). NSAIDs. [cited 2026 Oct 14]
- National Health Service (NHS). Paracetamol for adults: painkiller for pain and high temperature. [cited 2026 Oct 14]
- Acetaminophen. MedlinePlus Drug Information. Bethesda (MD): National Library of Medicine. [cited 2026 Oct 14]
- Pain Relievers. MedlinePlus. Bethesda (MD): National Library of Medicine. [cited 2026 Oct 14]
- National Health Service (NHS). Stomach ulcer. [cited 2026 Oct 14]
- National Health Service (NHS). Chronic kidney disease. [cited 2026 Oct 14]
- Central Drugs Standard Control Organisation (CDSCO). Drugs@CDSCO - aceclofenac, paracetamol and serratiopeptidase records. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare. [cited 2026 Oct 14]
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