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Zolpirest 5mg Tablets

10 Tablet(s) in Strip
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Zolpirest 5 MG Description

Zolpirest 5 mg tablet is a prescription medicine. It helps manage insomnia, a sleeping disorder that causes difficulties falling and staying asleep. The active ingredient in Zolpirest tablets is Z

olpidem. The mode of action of Zolpirest 5 mg tablets is to increase the activity of certain chemical messengers in the brain, that further lower excess brain activity and cause relaxation, leading to calmness and sleep. A proper dosage of Zolpirest tablet helps in managing insomnia. You should always take this medicine on the doctor's advice; otherwise, it can cause adverse effects like excessive drowsiness, fatigue, etc. Zolpirest tablets can also be habit-forming, meaning the user might depend on this medicine and have trouble sleeping without it. It can also cause unwanted sleep behaviours.


Product Summary

Offer Price₹42.12
You Save₹7.43 (15% on MRP)
ContainsZolpidem(5.0 Mg)
UsesInsomnia (sleeplessness)
Side effectsDrowsiness, Unsteady walking, Constipation, Changes in appetite, Stomach upset, Dry mouth, Muscle cramps or aches, Menstrual problems
Check more medicines with composition as Zolpidem(5.0 Mg)

Uses of Zolpirest 5 MG

  • As per CDSCO, Zolpirest 5 mg tablets can be used in the short-term management of insomnia characterised by difficulty in sleep initiation.

Contraindications of Zolpirest 5 MG

  • If you have a known hypersensitive reaction to Zolpidem or any component of this medicine.
  • If you are currently expecting or planning to conceive, Zolpirest tablets can cause low birth weight, preterm delivery and withdrawal symptoms in the baby at the time of birth.
  • If you have a history of addiction to alcohol, this medicine has a high potential for abuse and can cause both physical and psychological dependency.
  • If you are breastfeeding.
  • If you are experiencing sudden mood changes or have suicidal or other harmful thoughts.
  • If you take any narcotic or opioid pain relievers.
  • If you are diagnosed with any glaucoma (an eye disorder)
  • If you have respiratory problems like sleep apnea or asthma.
  • If you are at risk of sudden dizzy spells.
  • If you have myasthenia gravis (a muscle disorder).
  • If you are a child or adolescent under the age of 18.
  • If you have respiratory distress (slowing and declining of breathing).

Side effects of Zolpirest 5 MG

  • Drowsiness
  • Tiredness
  • Lightheadedness
  • Constipation
  • Changes in appetite
  • Difficulty keeping balance

Precautions and Warnings of Zolpirest 5 MG



Can I take Zolpirest 5 mg tablets during pregnancy?
No. Zolpirest tablets can be unsafe during pregnancy. This medicine may cause low birth weight, withdrawal effects in the baby, preterm labour, etc. A few studies have shown that it may lead to a definite risk to the developing foetus. Thus, do not take Zolpirest tablets without consulting your doctor.

Breast Feeding

Can I take Zolpirest 5 mg tablets while breastfeeding?
No. Consult a doctor if you want to take Zolpirest tablets while breastfeeding. There is only some data available on the effects of this medication on breastfed babies. Studies suggest that Zolpirest tablets pass into breast milk. Thus, avoid Zolpirest tablets without consulting a doctor.


Can I drive if I have taken a Zolpirest 5 mg tablet?
No. Do not drive after taking Zolpirest tablets. It can cause excessive drowsiness and blurred vision that can affect your ability to drive.


Can I consume alcohol with Zolpirest tablets?
No. Do not try to consume alcohol with Zolpirest tablets. Alcohol can interfere and alter the effectiveness of this medicine and result in increased side effects. This combination also increases the effects of alcohol.

Other General Warnings

Talk to your doctor if
  • You are an adult over 65; Zolpirest tablets may cause serious adverse effects due to slow metabolism in this age group.
  • You have a history of kidney, lung or liver disease.
  • You use Ayurvedic or herbal medicines or vitamins or supplements.
  • You experience disturbing sleep behaviours.
  • You have any fungal infections and are seeking treatment for them.
  • You are expecting or planning to conceive during the treatment.
  • You have any type of seizure disorder and are taking medications for it.

Mode of Action of Zolpirest 5 MG

How Does It Work?

Zolpirest tablets contain one active ingredient: Zolpidem. It belongs to the class of sedative-hypnotic medications (medicines that induce sleep and calmness). Zolpidem binds to certain receptors in t...
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Directions for Use of Zolpirest 5 MG

  • Take Zolpirest tablets precisely as advised by your doctor.
  • Do not exceed the dosage of Zopirest tablet, even if you cannot notice the effects of this medicine.
  • Take Zolpirest tablets as a whole with a glass of water.
  • Try to take this medicine before eating anything.
  • Do not break or chew this tablet.
  • Do not take Zolpirest tablets with other medications without informing your doctor.
  • Do not consume this medicine if its packaging is damaged.
  • Do not abruptly stop taking Zolpirest tablets; this can have adverse effects.

Interactions of Zolpirest 5 MG

Interactions with other medicines

  • Do not mix Zolpirest tablets with medicines that cause drowsiness, such as antihistamines (allergy medicines), opioid painkillers, muscle relaxants, sleeping pills, etc. This can cause excessive sleep...
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  • It is better not to take other sedatives like sertraline while under Zolpirest medication; this can enhance the side effects of this medicine.
  • Do not take Zolpirest tablets with certain antidepressants or mood-elevating medicines like amitriptyline and desipramine, as they can cause increased side effects such as drowsiness, fatigue, constip...
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  • Zolpirest tablets can reduce the effect of antifungal medications like itraconazole and ketoconazole. So if you are using these medicines together, dose adjustment is needed.

Interactions with food items

  • Take Zolpirest tablets on an empty stomach, ideally before meals. Food often delays the onset of sleep and slows down the absorption of the medicine.
  • Avoid coffee and caffeine-containing products that can increase the severity of sleeplessness or insomnia.

Storage and disposal of Zolpirest 5 MG

Store Zolpirest tablets in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humidity. Dispose of the packaging carefully after use. Check the expiration date before tak...
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Dosage of Zolpirest 5 MG


Zolpirest tablets overdose can cause symptoms like extreme drowsiness, lightheadedness, problems with coordination, confusion, loss of balance, trouble with speaking, yellowing of eyes and skin (due t...
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Missed a Dose

Zolpirest tablets should be taken on a need basis. It should never be taken more than the recommended dosage. It is okay if you take this medicine later than the usual time. This will only delay the ...
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Content Details


Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)


Q: Can I use more than one Zolpirest 5 mg tablet if I cannot sleep?

A: Use Zolpirest tablets in the exact dosage prescribed by your doctor. Do not use more than recommended. This is a habit-forming medicine. It can cause physical and psychological dependency if you use it for a long time. Hence, the dosage and duration of this medicine should be carefully monitored.

Q: Does daily use of Zolpirest 5 mg tablet cause sleepwalking?

A: Zolpirest tablets can cause sleep behaviours like sleepwalking in some people. Most people might not remember them. If you are experiencing such sleep conditions or patterns, seek consultation from your doctor immediately

Q: Can I take Zolpirest 5 mg tablets if I have depression?

A: No. Do not take Zolpirest tablets if you have been diagnosed with depression. This medicine can worsen the condition and cause unwanted effects. Consult your doctor for the proper treatment for depression.
Product Details
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Last Updated on: 11 Apr 2022 | 08:58 AM (IST)
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