It is mainly used before surgeries to prevent infection which may arise post-surgery like vaginal or abdominal surgeries to remove uterus, surgery to remove gall bladder stone or for jaundice, etc.
Contraindications of Zentim 1.125gm Inj
If you are allergic to Ceftriaxone and Tazobactam and any of the ingredient of this medicine
If you are allergic to Cephalosporins, Penicillins, Monobactams and Carbapenems
Should not be given to premature babies
If a newborn has jaundice or is on calcium injection treatment
If a newborn is suffering from increased bilirubin (liver enzyme) in blood
Side effects of Zentim 1.125gm Inj
Rash and severe skin allergies (Allergic dermatitis)
Bleeding disorder (coagulopathy)
Itching and pain at the injection site
Increased liver enzymes
Decrease in white blood cells and red blood cells
Increased number of eosinophils (Eosinophilia)
Increased creatinine levels in blood
Precautions and Warnings of Zentim 1.125gm Inj
Can I take Zentim 1.125gm Inj during pregnancy?
The effect of this medicine on the fetus is not clearly known, it must be used only if prescribed by your doctor
Consult your doctor if you are pregnant, think you are pregnant or planning a baby
Your doctor will give you this medicine after assessing the benefits over risks
Can I take Zentim 1.125gm Inj while breastfeeding?
This medicine passes in human milk in low amounts
The baby should be monitored for antibiotic-related side effects like diarrhoea or fungal infection of mouth
Your doctor will decide if the medicine should be discontinued when you are breastfeeding, only after assessing the benefit over risks
Can I drive if I have consumed Zentim 1.125gm Inj?
You may feel dizzy after taking this injection, thus be cautious or avoid driving after taking this injection.
Can I consume alcohol with Zentim 1.125gm Inj?
No information is available on interactions of this medicine when taken with alcohol. However, alcohol may worsen the side effect like dizziness. It is advisable to avoid alcohol if you have taken this injection
Other General Warnings
Talk to your doctor if
You have a history of allergy after taking the antibiotic
You have developed diarrhea after taking this medicine, immediately stop the medicine and inform your doctor
You have serious liver and kidney disease
You are suffering from gall bladder disease
You are suffering from anaemia
You are suffering from disease of bowel inflammation (Colitis)
Mode of Action of Zentim 1.125gm Inj
How Does It Work?
Zentim 1.125gm Inj acts by killing the bacteria responsible for infections.
However, bacteria make an enzyme (beta-lactamases) which can destroy Ceftriaxone
Tazobactam inactivates this enzyme and hence helps Ceftriaxone to function optimally
Directions for Use of Zentim 1.125gm Inj
This medicine will be given in the hospital by your doctor or nurse as an injection
Do not self inject this medicine
Interactions of Zentim 1.125gm Inj
Interactions with other medicines
There is limited information available on the interaction of this combination with other drugs. However, as this medicine contains Ceftriaxone and Tazobactam any interactions seen with these two components when taken alone may occur with this combination...
This injection should never be given along with Ringer's or Hartmann's solution
This medicine alters the action of oral contraceptives. Thus it is advisable to use alternative contraceptive measures like condoms when you are taking this medicine
This injection should never be given through the IV line through which calcium-containing solutions are given
Storage and disposal of Zentim 1.125gm Inj
Store it below 25°C protected from light
Keep it out of the reach of children
Any unused portion should not be stored and should be discarded properly
Dosage of Zentim 1.125gm Inj
Your doctor or nurse will give this injection, therefore chances of overdose are rare
However, if you experience nausea, vomiting, diarrhoea and stomach upset immediately after taking this injection, inform your doctor or reach out to your nearest hospital as soon as possible
Missed a Dose
You will be monitored by your doctor or nurse on when the medicine should be given to you
It is unlikely that the dose will be missed
However, if you think your doctor or nurse might have missed a dose, inform them
It is advisable not to miss any dose of antibiotics as it can result in failure of therapy
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