Trofev 100 Mg Strip Of 10 Capsules
10 Softgel Capsule(s) in StripMRP ₹650.00
₹487.50
25% OFF
Made by
HETERO HEALTHCARE LIMITED
Dosage
SOFTGEL CAPSULE
Expiry
Product Summary
| Salt Content | Nintedanib(100.0 Mg) |
| Uses | Idiopathic pulmonary fibrosis (IPF), Non-small cell lung cancer (NSCLC) |
| Therapy | Anti-neoplastic, drugs for idiopathic pulmonary fibrosis |
| Side effects | Nausea, vomiting, headache, stomach pain |
Assurance
available
Regulated
Medical Description
Trofev capsule is used to treat a rare lung disease known as Idiopathic Pulmonary Fibrosis (IPF). It is also prescribed for specific forms of lung cancer in combination with another anticancer medication called docetaxel. The active ingredient in Trofev capsule is nintedanib, which works by reducing the activity of certain enzymes called tyrosine kinases that contribute to fibrosis (scarring), thereby helping to slow the scarring of the lungs.
For optimal results, take Trofev capsule with food at the same time every day. Your doctor will determine the appropriate dosage and schedule for you, which may be adjusted as necessary. Follow your doctor's instructions carefully, as improper use or an overdose can lead to serious side effects. Do not discontinue this medication without consulting your doctor, even if it takes weeks or months to notice any benefits.
A very common side effect of this medicine is diarrhea. It is essential to drink plenty of fluids and consult your doctor if symptoms persist. Other common side effects may include nausea, stomach pain, vomiting, weight loss, high blood pressure, and headaches. Your doctor may also order blood tests to monitor your liver function.
Before starting Trofev capsule, inform your doctor if you have any bleeding problems or issues with your liver or kidneys. Additionally, please inform your healthcare team about all other medications you are taking, as many can interact with this medication. Trofev capsule is not recommended for use during pregnancy or while breastfeeding. To prevent pregnancy, both male and female patients are advised to use effective contraception during treatment.
Uses
Contraindications
- If you are allergic to nintedanib or any other ingredients of this medicine.
- If you are allergic to peanuts or soya.
- This medicine should never be used during pregnancy.
Side effects
- Nausea
- Vomiting
- Diarrhoea
- Headache
- Stomach pain
- Decreased appetite
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a liver, heart or family history of bleeding problems.
- You have a history of a blood-clotting disorder, or you smoke.
- You have had recent surgery in your stomach (abdominal) area.
- You are pregnant, planning a baby, or breastfeeding.
Directions for Use
- Trofev capsule should be taken as directed by your doctor.
- Swallow it whole with a glass of water; do not cut, break, or chew the medicine.
- It should be taken with food.
- It is best to take it at a fixed time for optimal results.
- You should not consume it more than that prescribed by your doctor.
Storage and disposal
- Store the Trofev capsule below 25°C. Protect from light and moisture.
- Keep it out of the reach and sight of children and pets.
Quick Tips
- Always take Trofev capsule with food and a full glass of water to reduce stomach irritation.
- Do not crush, chew, or break the capsule; swallow it whole.
- Take the medicine at the same time every day for the best results.
- If you miss a dose, skip it and continue with your next regular dose – never take a double dose.
- Stay hydrated, especially if you experience diarrhoea, and inform your doctor if it persists.
- Avoid smoking and alcohol, as they can reduce effectiveness or increase side effects.
Dosage
Missed a Dose
Overdose
Mode of Action
How Does It Work?
- Trofev capsule works by inhibiting the action of tyrosine kinases, an enzyme involved in the development of lung fibrosis. This enzyme is also involved in the process of forming new blood vessels in tumour cells.
- By inhibiting these enzymes, this medicine can help slow down scarring and the progression of cancer.
Interactions
Interactions with other medicines
- Certain medicines can affect the way the Trofev capsule works, or this medicine itself can interact with the action of other medicines taken concurrently.
- Therefore, it is essential to inform your doctor about all the medications, supplements, or herbal products you are currently taking or may take in the future.
- In particular, if you are taking a blood thinner, additional monitoring is required as Trofev capsule can increase the risk of bleeding.
- Concomitant administration of anti-infective medicines such as erythromycin and rifampicin; medicines for brain-related disorders such as phenytoin, carbamazepine and St. John’s wort should be avoided.
Interactions with food items
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:TROFEV
Country of Origin:India
Vendor Details
Fulfillment Information: Trofev 100 MG Softgel Capsule (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- NINTIB Capsules [Internet]. CiplaMed. 2025 [cited 27 March 2025]
- CDSCO | Nintedanib [Internet]. Cdscoonline.gov.in. 2025 [cited 27 March 2025]
- Conditions G. Idiopathic pulmonary fibrosis: MedlinePlus Genetics [Internet]. Medlineplus.gov. 2025 [cited 27 March 2025]
- Ofev 100 mg soft capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [cited 27 March 2025]
- DrugBank. Nintedanib. DrugBank Online. [cited 3 Mar 2025]
- Wind S, Schmid U, Freiwald M, Marzin K, Lotz R, Ebner T, Stopfer P, Dallinger C. Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib. Clin Pharmacokinet. 2019 Sep;58(9):1131-1147.[cited 3 Mar 2025]
- Gole S, Bankole A. Nintedanib. [Updated 2024 Aug 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; [cited 3 Mar 2025]
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
