Trixide Tablets
By TALENT INDIA
10 Tablet(s) in Strip
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Description
Trixide tablet is a prescription medicine used for treating symptoms of various psychological conditions, but mainly depression. Also, managing symptoms of various mood disorders such as anxiety and
panic disorder are one of Trixide tablets' main uses. Trixide tablet is a combination of two active ingredients, Amitriptyline and Chlordiazepoxide. This medication is a combination of an antidepressant and a benzodiazepine medicine. The mode of action of Trixide tablets is by decreasing the excess activity of nerves in the brain and stabilising mood. The medicine also generates a calming effect and sedation. You can take a Trixide tablet with or without food. Direction for use of Trixide tablets should be followed as instructed by the doctor because it can cause side effects. Most of them do not need any medical intervention as they subside gradually. However, if you're experiencing them for a long duration, consult your doctor.
Product Summary
| Offer Price | ₹30.32 |
| You Save | ₹9.58 (24% on MRP) |
| Contains | Amitriptyline(25.0 Mg)+Chlordiazepoxide(10.0 Mg) |
| Uses | Major Depressive Disorder, Anxiety Disorder, Panic Disorder |
| Side effects | Weight Gain, Constipation, Sedation, Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing), Dryness in Mouth, Urinary Retention, Blurred Vision. |
| Therapy | ANTI-DEPRESSANT |
Uses of Trixide Tablets
- As per CDSCO, Trixide tablet is used in the following conditions:
- In the treatment of the symptoms of major depressive disorder ( improves mood fluctuations and behaviour)
- In the management of symptoms of anxiety disorder, panic disorder, and other mood disorders
Contraindications of Trixide Tablets
If you have an allergic reaction to any of the ingredients of the Trixide tablet.
If you're pregnant, this medicine can have serious side effects on the unborn baby, especially in the third trimester.
If you're a breastfeeding woman.
If you've severe central nervous system depression (reduces central nervous system functionality of breathing).
If you've narrow-angle glaucoma (a condition with increased pressure in the eye).
If you're using other anti-anxiety or sedatives.
If you've a seizure disorder and are on antiepileptic (anti-seizure) medication.
If you have liver disease.
If you have a previous history of alcohol addiction or substance abuse, mental health disorder, etc....
Side effects of Trixide Tablets
- Nausea
- Constipation
- Dizziness
- Weight gain
- Dryness in mouth
- Blurred vision
- Urinary retention
- Orthostatic hypotension (sudden fall in blood pressure with position change)
Precautions and Warnings of Trixide Tablets
Pregnancy
Q:
Can I take the Trixide tablet during pregnancy?
A:
If you're pregnant, consult your doctor before taking a Trixide tablet. Trixide tablets can be unsafe to use during pregnancy. There is only some data available regarding the safety of this medicine in pregnant women. Still, animal research has shown some harmful effects in developing unborn babies.
Breast Feeding
Q:
Can I take the Trixide Tablet while breastfeeding?
A:
No, if you're a breastfeeding mother, don't take this medicine without consulting your doctor. There is no sufficient data on Trixide tablet effects on breastfeeding babies and mothers. Limited studies suggested that this medicine can pass into the breastmilk and cause unwanted effects in the baby.
Driving
Q:
Can I drive if I’ve taken the Trixide tablet?
A:
No, do not drive after taking the Trixide Tablet. It may cause adverse effects that could affect your ability to drive or operate heavy machinery. In some cases, you may experience blurring of vision, dizziness, mental confusion, nausea (mild), drowsiness, and other side effects.
Alcohol
Q:
Can I consume alcohol with the Trixide tablet?
A:
No, do not consume alcohol with a Trixide tablet. It exaggerates the effects of alcohol. They can interact and cause side effects like lightheadedness, nausea, vomiting, loss of consciousness, dizziness, etc.
Other General Warnings
Talk to your doctor if
- You have seizure syndrome.
- You are an elderly patient as dose adjustment is needed to prevent excessive side effects. Due to slow metabolism, this medicine is eliminated slowly from the body in them.
- You are under 18 years of age.
- You experience persistent side effects.
- You have a respiratory disease.
- You are using Ayurvedic or herbal medicines or supplements.
- You are planning for medical surgery or a dental procedure.
Mode of Action of Trixide Tablets
How Does It Work?
The Trixide tablet has two active ingredients, Chlordiazepoxide and Amitriptyline.
Chlordiazepoxide is a benzodiazepine class of medicine. It increases the activity of gamma-aminobutyric acid (GABA), which is a chemical messenger. GABA reduces the excessive action of nerve cells in the brain. It also blocks stomach acid production and lowers the anxiety associated with this disease.
Amitriptyline is a tricyclic antidepressant medicine. It works by lowering the reuptake of chemical substances like noradrenaline and serotonin, neurotransmitters present at the end of the nerve cells in the brain. This makes the effects of these substances last longer. Thus, Trixide Tablet helps regulate mood and aids in the treatment of depression. It relieves neuropathic pain by blocking the pain signals from the brain....
Directions for Use of Trixide Tablets
- Take the Trixide tablet in the recommended dose and duration.
- You can take a Trixide tablet with or without a meal.
- Do not take more than recommended dose at one time without informing the doctor, as this can lead to an overdose.
- Use it immediately after opening the package.
- Try to take the whole tablet with a glass of water, and do not break or chew the tablet.
- Check the expiration date before using this medicine.
Interactions of Trixide Tablets
Interactions with other medicines
- Do not use other antidepressant medicines like Fluoxetine, Paroxetine, etc., with Trixide tablets. This combination can increase serotonin levels and cause serotonin toxicity, leading to severe side effects and even death....
- It is better not to take other medicines that cause drowsiness, such as antihistamines (cetrizine), cold and cough medicine, opiates or narcotic pain relievers (codeine, tramadol), muscle relaxants, etc., with Trixide tablets. These medicines can increase the side effects of Trixide tablets and cause extreme drowsiness....
- It can be dangerous to use anti-anxiety and mood disorder treatments, such as linezolid, moclobemide, selegiline, etc., along with the Trixide tablet, as it can cause severe reactions. They inhibit serotonin metabolism and can result in serotonin levels that are high enough to cause Serotonin Syndrome, which can lead to life-threatening symptoms....
- If you have any known bleeding issues or take blood thinners, use caution when taking Trixide tablets, as this medicine increases the risk of bleeding in such persons.
- If you are already using antiepileptic medicines for seizure disorders, inform your doctor as these medicines can increase the side effects of Trixide tablets.
Interactions with food items
- Try to avoid eating grapefruit and its juice while on treatment with Trixide tablets. This fruit can increase the levels of this medicine in the blood.
- Trixide tablet does not have any other serious food interactions. Try to take Trixide tablets before or after consuming food. If you are experiencing an upset stomach, take it after the food.
Storage and disposal of Trixide Tablets
Store the Trixide tablets in a neat and dry place at room temperature. Take the tablet immediately after opening it. Do not expose Trixide tablets to direct sunlight, humidity, or wetness. Keep Trixide medicine away from pets and children.
Disposal - Dispose of this tablet’s package after use. Do not take the medication after its expiry date. Do not consume Trixide medicine if the package is already broken....
Dosage of Trixide Tablets
Overdose
Trixide tablet overdose can cause symptoms like severe drowsiness, dry mouth, abdominal pain, dizziness, fainting, vomiting, seizures, hallucination, sweating, cardiac arrest, agitation, involuntary movement of the muscles, liver failure (yellow skin and eyes), loss of consciousness, etc. In case of a Trixide tablet overdose, seek immediate medical treatment from the nearest medical centre....
Missed a Dose
If you have missed a dose of Trixide tablet, you can take it when you recall it. But, skip the missed dose of Trixide tablet if it's already time for the next one. Do not take both of them at a time or close together, as this can lead to an overdose....
Content Details
WRITTEN BY
REVIEWED BY
Dr. Varsha Parihar
MBBS, MD (Community Medicine)
Frequently Asked Questions (FAQs)
Q: Can a Trixide tablet cause physical dependency or addiction if I use it every day?
A: The regular use of Trixide tablets exposes the patients to the risks of abuse, misuse, or addiction. It can lead to overdose or death. Abuse and misuse of Trixide tablets commonly involve using them with other medications, alcohol, and recreational substances. It is associated with a high frequency of serious outcomes. Before prescribing Trixide tablets, your doctor will assess the patient’s risk for abuse, misuse, and addiction throughout the treatment.
Q: Can I gain weight if I use a Trixide tablet daily?
A: Weight gain is one of the most common side effects of this tablet. To avoid this, try exercising regularly and maintain a healthy lifestyle.
Q: Can I stop taking the Trixide tablet if I feel well?
A: No, you shouldn't stop taking this tablet even if you feel well. If you stop using the Trixide tablet suddenly, serious withdrawal problems may occur. The dose needs to be slowly tapered by the doctor if you want to stop the medicine.
References
View All
- Chlordiazepoxide and Amitriptyline (oral route) precautions [Internet]. Mayo Clinic. Mayo Foundation for Medical Education and Research; 2022 [cited 2022 Mar 19]. Available from:
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 2022 Mar 19]. Available from:
- DailyMed - chlordiazepoxide hydrochloride capsule [Internet]. U.S. National Library of Medicine. National Institutes of Health; [cited 2022 Mar 19]. Available from:
- DailyMed - chlordiazepoxide and amitriptyline hydrochloride tablet, film coated [Internet]. U.S. National Library of Medicine. National Institutes of Health; [cited 2022 Mar 19]. Available from:
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Product Details
Brand
TRIXIDE
Expires on or After
24/07/2025
Health Articles
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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