Trixide Tablets
10 Tablet(s) in StripWe do not sell this product
Made by
TALENT INDIA
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Amitriptyline(25.0 Mg)+Chlordiazepoxide(10.0 Mg) |
| Uses | Major Depressive Disorder, Anxiety Disorder, Panic Disorder |
| Therapy | Anti-depressant |
| Side effects | Weight Gain, Constipation, Sedation, Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing), Dryness in Mouth, Urinary Retention, Blurred Vision. |
Assurance
available
Regulated
Medical Description
Trixide tablet is a prescription medicine used for treating symptoms of various psychological conditions, but mainly depression. Also, managing symptoms of various mood disorders such as anxiety and panic disorder are one of Trixide tablets' main uses.
Trixide tablet is a combination of two active ingredients, Amitriptyline and Chlordiazepoxide. This medication is a combination of an antidepressant and a benzodiazepine medicine. The mode of action of Trixide tablets is by decreasing the excess activity of nerves in the brain and stabilising mood. The medicine also generates a calming effect and sedation.
You can take a Trixide tablet with or without food. Direction for use of Trixide tablets should be followed as instructed by the doctor because it can cause side effects. Most of them do not need any medical intervention as they subside gradually. However, if you're experiencing them for a long duration, consult your doctor.
Uses
- As per CDSCO, Trixide tablet is used in the following conditions:
- In the treatment of the symptoms of major depressive disorder ( improves mood fluctuations and behaviour)
- In the management of symptoms of anxiety disorder, panic disorder, and other mood disorders
Contraindications
If you have an allergic reaction to any of the ingredients of the Trixide tablet.
If you're pregnant, this medicine can have serious side effects on the unborn baby, especially in the third trimester.
If you're a breastfeeding woman.
If you've severe central nervous system depression (reduces central nervous system functionality of breathing).
If you've narrow-angle glaucoma (a condition with increased pressure in the eye).
If you're using other anti-anxiety or sedatives.
If you've a seizure disorder and are on antiepileptic (anti-seizure) medication.
If you have liver disease.
If you have a previous history of alcohol addiction or substance abuse, mental health disorder, etc.
Side effects
- Nausea
- Constipation
- Dizziness
- Weight gain
- Dryness in mouth
- Blurred vision
- Urinary retention
- Orthostatic hypotension (sudden fall in blood pressure with position change)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have seizure syndrome.
- You are an elderly patient as dose adjustment is needed to prevent excessive side effects. Due to slow metabolism, this medicine is eliminated slowly from the body in them.
- You are under 18 years of age.
- You experience persistent side effects.
- You have a respiratory disease.
- You are using Ayurvedic or herbal medicines or supplements.
- You are planning for medical surgery or a dental procedure.
Directions for Use
- Take the Trixide tablet in the recommended dose and duration.
- You can take a Trixide tablet with or without a meal.
- Do not take more than recommended dose at one time without informing the doctor, as this can lead to an overdose.
- Use it immediately after opening the package.
- Try to take the whole tablet with a glass of water, and do not break or chew the tablet.
- Check the expiration date before using this medicine.
Storage and disposal
Store the Trixide tablets in a neat and dry place at room temperature. Take the tablet immediately after opening it. Do not expose Trixide tablets to direct sunlight, humidity, or wetness. Keep Trixide medicine away from pets and children.
Disposal - Dispose of this tablet’s package after use. Do not take the medication after its expiry date. Do not consume Trixide medicine if the package is already broken.
Dosage
Overdose
Trixide tablet overdose can cause symptoms like severe drowsiness, dry mouth, abdominal pain, dizziness, fainting, vomiting, seizures, hallucination, sweating, cardiac arrest, agitation, involuntary movement of the muscles, liver failure (yellow skin and eyes), loss of consciousness, etc. In case of a Trixide tablet overdose, seek immediate medical treatment from the nearest medical centre.
Missed a Dose
If you have missed a dose of Trixide tablet, you can take it when you recall it. But, skip the missed dose of Trixide tablet if it's already time for the next one. Do not take both of them at a time or close together, as this can lead to an overdose.
Mode of Action
How Does It Work?
The Trixide tablet has two active ingredients, Chlordiazepoxide and Amitriptyline.
Chlordiazepoxide is a benzodiazepine class of medicine. It increases the activity of gamma-aminobutyric acid (GABA), which is a chemical messenger. GABA reduces the excessive action of nerve cells in the brain. It also blocks stomach acid production and lowers the anxiety associated with this disease.
Amitriptyline is a tricyclic antidepressant medicine. It works by lowering the reuptake of chemical substances like noradrenaline and serotonin, neurotransmitters present at the end of the nerve cells in the brain. This makes the effects of these substances last longer. Thus, Trixide Tablet helps regulate mood and aids in the treatment of depression. It relieves neuropathic pain by blocking the pain signals from the brain.
Interactions
Interactions with other medicines
- Do not use other antidepressant medicines like Fluoxetine, Paroxetine, etc., with Trixide tablets. This combination can increase serotonin levels and cause serotonin toxicity, leading to severe side effects and even death.
- It is better not to take other medicines that cause drowsiness, such as antihistamines (cetrizine), cold and cough medicine, opiates or narcotic pain relievers (codeine, tramadol), muscle relaxants, etc., with Trixide tablets. These medicines can increase the side effects of Trixide tablets and cause extreme drowsiness.
- It can be dangerous to use anti-anxiety and mood disorder treatments, such as linezolid, moclobemide, selegiline, etc., along with the Trixide tablet, as it can cause severe reactions. They inhibit serotonin metabolism and can result in serotonin levels that are high enough to cause Serotonin Syndrome, which can lead to life-threatening symptoms.
- If you have any known bleeding issues or take blood thinners, use caution when taking Trixide tablets, as this medicine increases the risk of bleeding in such persons.
- If you are already using antiepileptic medicines for seizure disorders, inform your doctor as these medicines can increase the side effects of Trixide tablets.
Interactions with food items
- Try to avoid eating grapefruit and its juice while on treatment with Trixide tablets. This fruit can increase the levels of this medicine in the blood.
- Trixide tablet does not have any other serious food interactions. Try to take Trixide tablets before or after consuming food. If you are experiencing an upset stomach, take it after the food.
Frequently Asked Questions (FAQs)
Articles
View All
Chronic Condition Articles
View All
Did you find this helpful?
Explore More at Pharmeasy
Manufacturer Details
Brand:TRIXIDE
Vendor Details
Fulfillment Information: Trixide Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Chlordiazepoxide and Amitriptyline (oral route) precautions [Internet]. Mayo Clinic. Mayo Foundation for Medical Education and Research; 2022 [cited 2022 Mar 19]. Available from:
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 2022 Mar 19]. Available from:
- DailyMed - chlordiazepoxide hydrochloride capsule [Internet]. U.S. National Library of Medicine. National Institutes of Health; [cited 2022 Mar 19]. Available from:
- DailyMed - chlordiazepoxide and amitriptyline hydrochloride tablet, film coated [Internet]. U.S. National Library of Medicine. National Institutes of Health; [cited 2022 Mar 19]. Available from:
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
