Pentasa Suppositories 28'S
Description
Pentasa Rectal Suppository contains mesalazine (also called mesalamine or 5-Aminosalicylic Acid) as its active ingredient. It is used to treat ulcerative colitis (a condition that causes inflammation
and ulcers in the linings of your large intestines) and prevents its symptoms from recurring. It works by stopping certain substances in the body that may cause inflammation. This medicine should only be taken after consulting a doctor and in doses and duration as prescribed. Pentasa Rectal Suppository is intended for rectal use only.
Product Summary
| Offer Price | ₹2605.50 |
| You Save | ₹544.50 (17% on MRP) |
| Contains | Mesalazine / Mesalamine / 5-Aminosalicylic Acid(1.0 G) |
| Uses | Ulcerative colitis |
| Side effects | Rash with or without itching Indigestion Fever Nausea and vomiting |
| Therapy | DRUGS FOR ULCERATIVE COLITIS |

Mesacol 1g Strip Of 7 Rectal SuppositoriesBy Sun Pharma7 Rectal Suppository(s) in StripMRP 426.56₹ 319.9250% CHEAPER₹ 45.70/Rectal Suppository
Mesarect 1gm Strip Of 7 Rectal SuppositoriesBy Meridian Enterprises Pvt Ltd7 Rectal Suppository(s) in StripMRP 309.37₹ 232.0264% CHEAPER₹ 33.15/Rectal Suppository
Vegaz 1gm Strip Of 7 SuppositoriesBy Dr Reddy's Laboratories Ltd7 Rectal Suppository(s) in StripMRP 324.37₹ 249.7661% CHEAPER₹ 35.68/Rectal Suppository
Uses
- Pentasa Rectal Suppository is used in treating ulcerative colitis.
Contraindications
- If you are allergic to mesalazine or any other ingredients of Pentasa Rectal Suppository.
- If you have any problems with your liver or kidney.
- If you are allergic to salicylates (Diclofenac, aspirin, Ibuprofen, etc.).
Side effects
- Rash with or without itching
- Indigestion
- Fever
- Nausea and vomiting
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have any liver or kidney-related problems.
- You have any lung diseases like asthma.
- You have any problems with your heart (like any allergic reactions).
- You have experienced an allergic reaction while taking sulfasalazine.
- You may develop kidney stones (symptoms like stomach pain and blood in urine) while on treatment with this medicine. Hence it would help if you drink plenty of water.
- Before and during treatment with Pentasa Rectal Suppository, your doctor may want to monitor the liver, kidneys, blood and lungs periodically.
- It is recommended to ensure adequate fluid intake during treatment.
Mode of Action
How Does It Work?
Directions for Use
- For rectal use only. Use this medicine as prescribed by your doctor.
- Wash and dry your hands after emptying your bowel.
- Insert the suppository in your rectum region through the anal opening after peeling off any wrapping over it.
- Do not move or walk for 15 minutes so that the medicine starts dissolving due to the body's temperature.
- Rewash your hands.
- Avoid passing stools for at least 1 hour so that medicine stays in place.
Interactions
Interactions with other medicines
- You should always tell the doctor if you are taking any other medicines, herbal preparation and supplements to avoid any interaction with Pentasa Rectal Suppository.
- You need to be cautious while simultaneously taking this medicine along with medicines like azathioprine, 6-mercaptopurine (used in rheumatoid arthritis, Crohn's disease), and thioguanine (used in cancer treatment)....
- This medicine, when taken along with blood thinners like warfarin (used to prevent blood clot formation), may decrease the effect of warfarin.
Storage and disposal
- Store Pentasa Rectal Suppository in a cool and dry place, protected from direct sunlight, moisture and heat.
- Keep it away from children and pets. Do not use expired or damaged medicines.
- Discard any unused medicine properly, do not flush it in the toilet or throw it into the drain.
Dosage
Overdose
- Seek urgent medical help if you feel that you have taken too much of Pentasa Rectal Suppository.
Missed a Dose
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: How long to take Pentasa Rectal Suppository?
Q: What should I discuss with my healthcare expert before using Pentasa Rectal Suppository?
- Inform the doctor about your detailed medical & surgical history.
- Inform your doctor if you have heart, liver or kidney disease.
- Inform your doctor if you are pregnant, breastfeeding or planning to have a baby.
Q: Is Pentasa Rectal Suppository addictive?
Q: What is the composition of Pentasa Rectal Suppository?
References
- Octasa 400 mg Modified Release Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 15 Jan 2026]
- Octasa 400 mg Modified Release Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 15 Jan 2026]
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 15 Jan 2026]
- PENTASA® Suppositories 1g - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 15 Jan 2026]
Did you find this medicine information helpful?
Please rate your experience
Blog Articles
Chronic Condition Articles
Top-Tests we cover:
Top-Selling Healthcare Products:
Top-Selling Medicines:
Top-Searched Medicines:
Top Searched Vaccines:






















