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Patroxta Plus 12.5mg Tablet

10 Tablet(s) in Strip
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Patroxta Plus 12.5mg Tablet Description

Patroxta Plus Tablet is used for the treatment of Depression, Anxiety disorder and Panic disorders (sudden or unexpected attacks of extreme fear and worry). Depression is a mood disorder characterise

d by an episode of sadness, mood swings, loss of interest, hopelessness etc. Patroxta Plus is a combination of two components, Paroxetine and Clonazepam. Together, this combination of medicine increases serotonin levels in the brain and reduces the nerve cells' abnormal activity in the brain. Serotonin is a natural chemical messenger responsible for controlling behavioural processes such as mood, fear, anger, appetite, memory etc. The dose of Patroxta Plus should be taken as advised by your doctor. There are some side effects associated with this medicine, so it is advised to take it after the doctor’s consultation. This medicine may cause physical dependence if used for a long duration or in people who have a history of addiction. So, the dosage must be carefully monitored.


Product Summary

Offer Price₹148.06
You Save₹24.10 (14% on MRP)
ContainsParoxetine(12.5 Mg) + Clonazepam(0.5 Mg)
UsesDepression, Anxiety disorder, Panic disorder, Post-traumatic stress disorder (PTSD)
Side effectsNausea, Vomiting, Diarrhoea, Confusion, Dizziness, Insomnia, Memory impairment
Check more medicines with composition as Paroxetine(12.5 Mg) + Clonazepam(0.5 Mg)

Uses of Patroxta Plus 12.5mg Tablet

  • As per CDSCO and USFDA, Patroxta Plus is used for the following:
  • Treatment of depression
  • Treatment of anxiety disorder
  • Treatment of the panic disorder
  • Treatment for Post-traumatic stress disorder (PTSD)

Contraindications of Patroxta Plus 12.5mg Tablet

  • It is contraindicated in the following cases:
  • If you are allergic to any components of Patroxta Plus, i.e. Paroxetine and Clonazepam
  • If you are taking antidepressant-like Monoamine Oxidase Inhibitors (MAOIs)
  • If you are using other anti-anxiety or sedative medicines and antipsychotic medications
  • If you have eye disorder like narrow-angle glaucoma
  • If you have liver or kidney disease
  • If you have respiratory issues
  • If you have a heart condition
  • If you are pregnant or a breastfeeding mother

Side effects of Patroxta Plus 12.5mg Tablet

  • Side effects of Patroxta Plus include the following:
  • Nausea
  • Vomiting
  • Diarrhoea
  • Confusion
  • Dizziness
  • Insomnia
  • Memory impairment

Precautions and Warnings of Patroxta Plus 12.5mg Tablet



Can I take Patroxta Plus during pregnancy?
Patroxta Plus is unsafe during pregnancy. Some clinical studies have shown a definite risk to unborn babies. Sometimes your doctor may prescribe this medicine during serious life-threatening conditions if they think the benefits outweigh the risks. Do not take Patroxta Plus without consulting your doctor.

Breast Feeding

Can I take Patroxta Plus while breastfeeding?
Patroxta Plus is not recommended during breastfeeding as it may get excreted into breast milk and can harm the baby. Consult your doctor before taking this medicine to discuss the potential risks and benefits of taking this medicine.


Can I drive if I have taken Patroxta Plus?
Patroxta Plus may cause side effects that could hamper your driving ability. The tablet may decrease alertness, affect your vision and can cause a decrease in reflexes, dizziness, lethargy and lightheadedness. Avoid driving if you are experiencing these side effects after taking this medicine.


Can I consume alcohol with the Patroxta Plus?
Do not consume alcohol with the Patroxta Plus tablet. It can interfere with the function of the medicine and cause exaggerated side effects.

Other General Warnings

Talk to your doctor if
  • You have any allergic reactions after taking Patroxta Plus.
  • You have any suicidal ideation or self-harming thoughts.
  • You notice sudden or severe changes in thought, behaviour or mood.
  • You notice a sudden decrease in vision.
  • You have trouble breathing or talking,
  • You have withdrawal symptoms like agitation, nausea, tremor, sweating and confusion.
  • You are using any ayurvedic/ herbal medicines, vitamins and other health supplements.

Mode of Action of Patroxta Plus 12.5mg Tablet

How Does It Work?

Patroxta Plus is a combination of two medicines containing Paroxetine (12.5 mg) and Clonazepam (0.5 mg). Paroxetine is an antidepressant medicine that belongs to the Selective Serotonin Re-uptake Inhi...
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Directions for Use of Patroxta Plus 12.5mg Tablet

  • Take the Patroxta Plus exactly as prescribed by the doctor.
  • Take this medicine with or without food or as prescribed, preferably at the same time every day.
  • Take the tablet as a whole orally with water. Do not break or crush the tablet or chew this medicine.
  • Do not take this tablet with other medications without consulting your doctor.
  • Do not stop taking this medication suddenly, as it may lead to withdrawal side effects.
  • Do not exceed the dosage on your own without consulting a doctor.

Interactions of Patroxta Plus 12.5mg Tablet

Interactions with other medicines

  • Patroxta Plus interaction with MAOI (monoamine oxidase inhibitors) like Selegiline, Rasagiline, Isocarboxazid, and antidepressants, lithium, triptans, buspirone, amphetamines, tramadol, tryptophan, is...
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  • Patroxta Plus interaction with metoprolol can lead to excessive bradycardia (slow heart rate).
  • Patroxta Plus interaction with antipsychotics (haloperidol, pimozide), antihistamines and tricyclic antidepressants can prolong QT interval on ECG and alter heart rhythm.
  • Patroxta Plus interaction with NSAIDs, aspirin, and other medications increase the risk of bleeding.
  • Patroxta Plus interaction with herbal products like St John’s wort can lead to life-threatening side effects

Interactions with food items

  • Avoid consuming Patroxta Plus with cola drinks, chocolates and caffeine-containing food items like tea or coffee as it can result in serotonin syndrome (high levels of serotonin).

Storage and disposal of Patroxta Plus 12.5mg Tablet

Store Patroxta Plus at room temperature in a cool and dry area, away from humidity and direct sunlight. Keep the medication away from children and pet animals. Do not remove the medicine from its pack...
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Dosage of Patroxta Plus 12.5mg Tablet


Overdose of Patroxta Plus can lead to toxicity or poisoning. It may cause symptoms like nausea, vomiting, respiratory dysfunction, changes in heart rate, difficulty walking, convulsion and coma. If yo...
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Missed a Dose

If you have missed a dose of Patroxta Plus, take it as soon as you remember. If you remember missing a dose of this tablet when it is already time to take the next one, skip the missed dose and take t...
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Content Details


Dr. Zishan Ahmad

Final year MBBS Student


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Does taking Patroxta Plus cause weight gain?

A: Patroxta Plus is known to cause changes in appetite and lethargy, resulting in weight gain, especially if used for a longer duration. If you notice any weight changes, Eat healthily and exercise regularly to avoid weight gain.

Q: Can I take a Patroxta Plus with other prescribed medications?

A: Taking other medications with Patroxta Plus may lead to interaction with other medicines that can be serious or life-threatening. Tell your doctor about all the medicines you take or plan to take and your past medical history before taking this medicine.

Q: Can I discontinue Patroxta Plus on my own after I feel improvement in my symptoms?

A: No, suddenly stopping Patroxta Plus can cause withdrawal symptoms like agitation, nausea, tremor, confusion, diarrhoea, vomiting, and sweating. Consult your doctor before stopping Patroxta Plus, as doses need to be tapered slowly to avoid undesirable side effects.
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Last Updated on: 24 Mar 2022 | 09:40 PM (IST)

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