Nildep 10mg Tablet
By D D PHARMACEUTICALS
10 Tablet(s) in Strip
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Description
Nildep Tablet belongs to a class of medicines known as tricyclic antidepressants. It is primarily used for the treatment of depression. Nildep Tablet contains Imipramine as an active ingredient. It w
orks by affecting the levels of certain chemical messengers in the brain, which help stabilise the mood of the affected person. Depression is a severe mental disorder in which a person's ability to think, feel and behave is seriously hampered. By virtue of its effect on the chemical messengers, this medicine helps the person feel better.
Product Summary
| Offer Price | ₹17.86 |
| You Save | ₹5.34 (23% on MRP) |
| Contains | Imipramine(10.0 Mg) |
| Uses | Depression, bedwetting in children |
| Side effects | Weight gain, increased sensitivity to sunlight, tiredness, nightmares. |
| Therapy | ANTI-DEPRESSANT |
Uses
- Depression
- Treating bedwetting in children six years and above.
Contraindications
- If you are allergic to the medication.
- If you have Schizophrenia.
- If you have suicidal tendencies.
- If your thyroid gland is overactive.
- If you have acute angle-closure glaucoma (wherein the pressure inside the eye is increased due to blockage in the fluid drainage).
- If you have a history of a recent heart attack (less than one month).
- If you have alcohol intoxication.
Side effects
- Abdominal discomfort
- Tachycardia (increased heart rate)
- Blurring of vision
- Dryness of mouth
- Difficult urination
- Constipation
- Postural hypotension( sudden drop in blood pressure from lying down to standing position.
- Sexual dysfunction.
- Increased sweating.
Precautions and Warnings
Pregnancy
Q:
Can I take Nildep Tablet during pregnancy?
A:
There is a limited number of studies on Nildep Tablet use during pregnancy. Some studies have shown risk to the developing baby. Always take the advice of your physician; he knows things better.
Breast Feeding
Q:
Can I take Nildep Tablet while breastfeeding?
A:
No, it must not be taken, as it gets secreted in the milk and can adversely affect the baby.
Driving
Q:
Can I drive if I have taken Nildep Tablet?
A:
No, avoid driving, as Nildep causes drowsiness.
Alcohol
Q:
Can I consume alcohol with the Nildep Tablet?
A:
No, you must avoid alcohol as the chances of side effects are life-threatening.
Other General Warnings
Talk to your doctor if
- You feel sudden changes in your mood, behaviour or develop suicidal tendencies.
- You have deranged liver function tests as this would require dose adjustments.
- You have to undergo any surgery in future, as this medicine needs to be stopped well before any surgery.
- You have bipolar disorder, as symptoms of mania may aggravate further.
Mode of Action
How Does It Work?
Nildep Tablet contains Imipramine as an active ingredient. Imipramine belongs to the class of medicines known as tricyclic antidepressants. It works mainly by working at the level of two essential chemical messengers, also known as neurotransmitters, serotonin and noradrenaline. Serotonin, the "happiness hormone", makes a person feel happy, free from anxiety and tension. Noradrenaline also improves mood and increases alertness and arousal. Nildep works by preventing the reuptake (the process by which these messengers are taken back ) of serotonin and noradrenaline....
Directions for Use
- Take this tablet with a glass of water as a whole.
- It can be taken with or without food.
- Do not try to break the tablet or chew it.
- Take it for as long as you are advised. Do not decrease or increase the dose on your own, use it as per the directions from your doctor.
- Do not abruptly stop taking this medicine, leading to withdrawal symptoms.
- Your dose needs to be modified or gradually decreased before discontinuation.
- Preferably you must take the medication at bedtime as this can make you feel drowsy.
Interactions
Interactions with other medicines
- MAO inhibitors (Monoamine oxidase inhibitors) like Selegiline, interact with Nildep, as both increases, the level of serotonin which can be life-threatening (this can lead to "serotonin syndrome", which is a life-threatening condition)...
- Low dose aspirin increases the blood levels of Imipramine and can lead to toxicity.
- Aripiprazole (an antipsychotic medicine), if taken with Imipramine, can increase the side effects like drowsiness, increased sweating, dry mouth, Blurring of vision etc.
- Rifampicin (a medicine used in the treatment of tuberculosis) can decrease the blood levels of Imipramine due to increased metabolism through a process called enzyme induction)
Interactions with food items
- No interactions found.
Storage and disposal
Store Nildep tablets in a cool and dry place. Keep this medication out of the reach of children and pets. Do not use the medicine if the packaging is damaged. Don't freeze. Get a new pack of medicine in such a case. Talk to your pharmacist if there is some leftover medication or talk to your doctor regarding this.
Don't use the medication if the date of expiry has passed....
Dosage
Overdose
Symptoms of overdose include, dizziness, confusion, fast heart rate , seizures, palpitations, drop in blood pressure.
Rush the person immediately to a nearby health care facility.
You can call the emergency helpline....
Missed a Dose
Consume the missed dose as soon as possible. Do not double the dose on your own. Try to have the medicine at the same time in a day so that you don't forget.
Content Details
WRITTEN BY
Dr. Varsha Parihar
MBBS, MD (Community Medicine)
REVIEWED BY
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: Is Nildep Tablet habit-forming?
A: No, it is not habit-forming. But it can produce withdrawal symptoms if stopped suddenly.
Q: Can Nildep Tablet be taken in case of kidney problems?
A: It needs dose adjustments in case of kidney problems.
Q: Can Nildep be prescribed to a person who has issues with prostate?
A: If that person doesn't have urinary retention, which can happen with prostate issues, Nildep can be given; otherwise, not. As this medication sometimes can lead to urinary retention.
References
View All
- Imipramine Hydrochloride Tablets USP 10 mg, 25 mg, and 50 mg [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 14 April 2020]. Available from:
- Internet]. Medicines.org.uk. 2020 [cited 14 April 2020]. Available from:
- Imipramine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 14 April 2020]. Available from:
- Medicines.org.uk. 2020 [cited 14 April 2020]. Available from:
- Imipramine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 14 April 2020]. Available from:
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Product Details
Brand
NILDEP
Expiry Date
10/12/2025
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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