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Mertabto 10Mg Strip Of 10 Tablets

10 Tablet(s) in Strip

MRP49.70

39.76

20% OFF

3.98/tablet (Inclusive of all taxes)
7 days return policy Read More
Offer applicable on order above ₹1000
  • Mertabto 10Mg Strip Of 10 Tablets
  • Mertabto 10Mg Strip Of 10 Tablets

Made by

EMCURE PHARMACEUTICALS LTD

Dosage

TABLET

Expiry

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Product Summary

Uses
Anticancer
Side effects
Nausea, vomiting, and loss of appetite
Salt Content
Mercaptopurine(10.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Mertabto tablet is a prescription anticancer medication that belongs to a class of drugs called antimetabolites (specifically a purine analogue). It is primarily used to treat acute leukaemias, such as acute lymphoblastic leukaemia (ALL). It works by interfering with DNA synthesis, thereby inhibiting the growth and division of leukaemia cells.

It is available as oral tablets and should be taken exactly as prescribed. The dose may be adjusted based on regular blood tests and how the treatment responds.

Treatment requires close medical monitoring, including regular blood counts and liver function tests, due to the risk of bone marrow suppression, infections, and liver toxicity. Long-term treatment may also carry a risk of secondary malignancies.

Uses

Treatment of acute leukaemias, including acute lymphoblastic leukaemia (ALL)

Contraindications

  • If you have a known hypersensitivity or severe allergic reaction to mercaptopurine or any of the inactive ingredients.
  • If you have severe bone marrow suppression, your doctor will assess whether treatment should be started or continued.
  • If you are pregnant or breastfeeding. Use it during pregnancy only when clearly necessary and under medical supervision.

Side effects

Very common side effects (occurring frequently):
  • Bone marrow suppression leading to low white blood cell count (neutropenia), low red blood cell count (anemia), and low platelet count (thrombocytopenia)
  • Nausea, vomiting, and loss of appetite
  • Liver function test abnormalities
Other reported side effects:
  • Diarrhea and abdominal pain
  • Mouth sores (stomatitis)
  • Skin rash, itching, or hyperpigmentation
  • Temporary hair thinning or hair loss
Serious but less common side effects:
  • Severe, life-threatening infections (due to suppressed immune system)
  • Liver toxicity (jaundice, severe hepatotoxicity)
  • Pancreatitis (severe abdominal pain radiating to the back)
  • Secondary malignancies, including lymphoproliferative disorders and other malignancies, have been reported, particularly with long-term immunosuppressive use.
  • Severe hypersensitivity reactions

Precautions and Warnings

Pregnancy

Pregnancy

Tell your doctor if you are pregnant or planning to become pregnant. Mertabto tablet should be used during pregnancy only when clearly necessary and under medical supervision.

Breast Feeding

Breast Feeding

Tell your doctor if you are breastfeeding. Your doctor will decide whether to continue breastfeeding during treatment based on your clinical situation.

Driving

Driving

Use caution. Mertabto tablet can cause side effects such as fatigue or dizziness that may impair your alertness. Avoid driving if you feel unwell.

Alcohol

Alcohol

It is best to limit or avoid alcohol during treatment, as it can worsen liver strain, increase nausea, and interfere with your overall recovery.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have pre-existing liver or kidney impairment, as dosage adjustments may be necessary.
  • You experience signs of an active infection, such as fever, chills, or persistent cough.
  • You develop severe abdominal pain, particularly if associated with nausea or vomiting, as this may indicate pancreatitis.
  • You are starting a new medication, particularly for gout, as this requires an immediate review of your dosage.

Directions for Use

  • Take Mertabto tablet orally exactly as prescribed by your doctor, usually once daily.
  • Swallow the tablets whole with a glass of water; do not crush, split, or chew them.
  • You may take mercaptopurine consistently with or without food; follow the same method each day unless your doctor advises otherwise.
  • Wash your hands thoroughly after handling the tablets and keep them out of reach of children.

Storage and disposal

  • Store the tablets at room temperature in their original container, protected from light and moisture.
  • Keep out of the reach of children and pets.
  • Do not keep expired or unwanted tablets; return unused medicine to your pharmacist for safe disposal.

Quick Tips

  • Keep all scheduled blood test appointments so your doctor can monitor your blood counts and liver enzymes.
  • Report any fever, chills, sore throat, or signs of infection to your doctor immediately.
  • Watch for unusual bruising, tiny red spots on the skin, or bleeding from the gums or nose.
  • If you develop persistent nausea or yellowing of the skin or eyes (jaundice), contact your medical team right away.
  • Tell all your healthcare providers you are taking this medication before any other medical procedures or dental work.

Dosage

Overdose

If an overdose is suspected, seek immediate medical intervention in a hospital setting. Symptoms of an overdose can include severe nausea, vomiting, profound bone marrow suppression, and signs of liver damage. Management involves supportive hospital care, monitoring of blood counts, and close clinical observation.

Missed a Dose

If you miss a dose, do not take a double dose to make up for it. Take your next dose at the regular scheduled time. Contact your doctor or clinic if you are unsure about your dosing instructions.

How does this medicine work?

Mertabto tablet is a purine analogue antimetabolite that interferes with DNA and RNA synthesis. It acts as a false building block, disrupting the replication of rapidly dividing cells such as leukaemia cells and inhibiting their growth and multiplication.

Interactions

Interactions with other medicines

  • Avoid live vaccines during treatment unless your doctor specifically advises them.
  • Inform your doctor about all prescription drugs, over-the-counter medicines, and herbal supplements you are taking, especially allopurinol (a gout medication) or febuxostat, as these can significantly increase mercaptopurine exposure and may require substantial dose adjustment.
  • Use caution with other drugs that cause bone marrow suppression or liver toxicity.

Interactions with food items

  • You can take mercaptopurine with or without food, but take it consistently in the same way each day.
  • Maintain a balanced diet and stay well-hydrated throughout your treatment course.
  • Avoid excessive alcohol consumption, as it may increase the risk of liver problems.

Frequently Asked Questions (FAQs)

This medication can suppress your bone marrow, reducing the production of white blood cells, red blood cells, and platelets. Frequent blood tests allow your doctor to ensure these counts are safe; your dose may need to be adjusted or temporarily paused based on these results to prevent severe infections or bleeding.
Dosage is individualized based on factors such as your treatment regimen, blood counts, response to treatment, and how your body processes the medicine. TPMT and NUDT15 testing may be considered in patients with severe or repeated myelosuppression.
Allopurinol significantly increases mercaptopurine levels in your body and increases the risk of toxicity. Always tell your doctor if you are prescribed allopurinol (or other gout medications) before starting or while taking mercaptopurine, as your dose will need to be reduced significantly.
Watch for yellowing of the skin or the whites of your eyes (jaundice), dark-coloured urine, light-coloured stools, or persistent upper-right abdominal pain. If you notice any of these, contact your doctor immediately.
Treatment length depends on your diagnosis and treatment regimen. For acute leukaemia, mercaptopurine is commonly used as part of combination chemotherapy, including maintenance therapy for ALL

References:

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Manufacturer Details

Brand:MERTABTO

Manufacturer Name:EMCURE PHARMACEUTICALS LTD

Address:EMCURE PHARMACEUTICALS LTD

Country of Origin:India

Vendor Details

Fulfillment Information: Mertabto 10 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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