Glimestar M1 Forte Tablets

• If you are allergic to metformin, glimepiride or any of the ingredients of the Glimestar-M1 Forte tablet.
• If you are pregnant or are breastfeeding.
• If you have serious kidney failure or liver failure.
• If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
• If you have dehydration, severe infections, shock and injections containing iodine.
• If you have had heart or lung failure, the recent incidence of heart attack and shock.
• If you are an alcoholic.

• Vomiting
• Nausea
• Diarrhoea
• Stomach pain
• Loss of appetite
• Metallic taste
• Low blood sugar level which can cause a headache, sweating, nausea, mood disorders and restlessness.

Other General Warnings

• You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, immediately have sugar or sweet juice. Inform your doctor as you may need a change in your medicine's dose.
• You are experiencing pins-and-needles sensation, numbness and weakness.
• You are going to have a diagnostic imaging test that involves the injection of iodine.
• You have dehydration due to diarrhoea, vomiting or limited fluid intake.
• You have suffered through trauma.
• You have to undergo surgery in the near future.
• You have serious kidney and liver problems.
• You have a thyroid disorder.
• You are overweight (specific diet restriction may be suggested).

• Store it at room temperature in a dry place.
• Protect it from moisture.
• Keep it out of the reach of children.

• Glimestar-M1 Forte tablet is an anti-diabetic medicine. It is used for the management of type 2 diabetes mellitus. It contains a combination of glimepiride and metformin as active ingredients.
• Take this medicine in the exact dose and duration prescribed by the doctor. Do not take more than the prescribed dose.
• Along with taking Glimestar-M1 Forte tablet, it is essential that you do certain lifestyle modifications like exercising regularly, avoiding smoking and drinking alcohol.
• It is also advised to have a balanced diet with adequate fruits and vegetables for good control of your blood sugar levels.
• Before starting Glimestar-M1 Forte tablet, inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.
• Headache, stomach pain, restlessness and nausea/vomiting may occur in some individuals with the use of this medicine. Inform your doctor if these effects bother you or do not go away.
• Talk to your doctor if you have kidney or liver disease.

Overdose

• An overdose of this medicine may lead to severe hypoglycemia and lactic acidosis (Excessive lactic acid build-up) & low blood sugar. This can result in headaches, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, depression, confusion, dizziness, etc.
• If you experience these, immediately take glucose or juice or sugar-containing products (Sugar candy).
• Contact your doctor immediately or visit the nearest hospital as you may require close monitoring for the next few hours.

Missed a Dose

• A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, the fruity smell from breath, etc.
• If you have missed taking any dose of medicine, take it as soon as you remember.
• If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
• Do not take a double dose of medicine to compensate for the missed one.

How Does It Work?

• This combination is known to control blood sugar to a greater extent than metformin or glimepiride alone Glimiperide lowers the blood sugar level increasing release of insulin hormone from the pancreas.
• Insulin moves sugar (glucose) from the blood into the cells.
• Metformin decreases the absorption in the intestine and the production of sugar by the liver.
• Both of these components are known to increase the insulin sensitivity of the body (allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Interactions with other medicines

• Sometimes the Glimestar-M1 Forte tablet may affect the way other medicines work and other medicines may affect how the Glimestar-M1 Forte tablet works if taken at the same time.
• You may have symptoms of low blood sugar if you are taking other medicines for diabetes like Insulin, anti-hypertensive medicine like captopril, steroids, cholesterol-lowering medicines, medicines related to mood disorder, immunosuppressants, anti-gout medicines like probenecid, antibiotics like clarithromycin, ofloxacin, etc.
• You may have symptoms of high blood sugar if you are taking oral contraceptives, Acetazolamide, water pills, Anti-epileptic medicine like phenytoin, anti-tuberculosis medicine like rifampicin, medicines for constipation and medicines for thyroid disorders.
• Medicines like Diclofenac, Ibuprofen, Water pills, Enalapril may affect your kidney functions if taken along with this medicine.
• Medicines used to treat thyroid can affect the way this medicine works.