Eptus 25 Tablet

• Eptus 25 tablet is a diuretic medication primarily used for treating hypertension (high blood pressure). It helps maintain the body's potassium level, eliminates excess water, and prevents hypertension caused by fluid retention (oedema).
• It also helps to reduce the risk of heart-related complications and deaths in adults with chronic heart failure.

• If you are allergic to eplerenone or any other components of this medicine.
• If you have high potassium levels in the blood.
• If you have severe liver or kidney problems.
• With other salt tablets or potassium-sparing diuretics (water pills which increases the level of potassium in the blood).
• If you are using the medicines such as ketoconazole, itraconazole (medicines to treat fungal infections), medicines used to treat HIV infection nelfinavir, ritonavir, antibiotics such as clarithromycin or telithromycin and medicines used in heart diseases such as angiotensin-converting enzyme inhibitor and an angiotensin receptor blockers.

• Increased Potassium levels
• Sleeplessness
• Dizziness
• Headache
• Low blood pressure
• Vomiting
• Back pain
• Muscle cramps
• Weakness

Other General Warnings

• You have any kidney or liver problems.
• You are taking medicines like lithium (used for mental illness).
• You are taking medicines like tacrolimus or cyclosporine (used to treat skin conditions such as psoriasis or eczema and to prevent rejection after organ transplantation).
• Your doctor may advise a blood test before and during therapy with this medicine to measure the blood potassium levels, especially, if you are suffering from any kidney or liver problems.

• Take Eptus Tablet as a whole with a sufficient amount of water. Do not break or chew the medicine.
• Always take this medicine exactly as your doctor has told you.

• Keep Eptus Tablet out of the sight and reach of children and pets.
• Do not use this medicine after its expiry date.
• Store it below 30°C in the original packaging.
• Do not throw away any medicines via wastewater or household waste.

• Eptus 25 mg tablet is a medication used to treat hypertension (high blood pressure) and to reduce the risk of cardiovascular mortality and morbidity in adult patients with chronic heart failure.
• It is prescribed as an add-on therapy to standard treatments for heart failure.
• Eptus 25 mg tablet helps improve heart health and lower the chances of severe heart-related complications and deaths.
• It is essential to take this medication exactly as prescribed by your doctor and not miss any doses.
• Inform your healthcare provider about any other medications or supplements you are taking to avoid potential drug interactions.
• If you experience any unusual side effects or allergic reactions while taking Eptus 25 mg Tablet, seek immediate medical attention.
• Regularly follow up with your doctor to monitor your response to the treatment and adjust the dosage if needed for better management of your heart condition.

Overdose

Missed a Dose

• Eptus 25 Tablet contains eplerenone, which sits on the mineralocorticoid receptor and prevents the hormone aldosterone from binding to it. Aldosterone normally instructs the kidney to hold on to sodium and water and to excrete potassium.
• Blocking that instruction allows excess sodium and water to leave the body in the urine, reducing fluid overload and easing the load on a weakened heart, while potassium is retained rather than lost.
• Aldosterone also promotes fibrosis, the laying down of scar tissue in the heart muscle and blood vessel walls, which stiffens them and worsens heart failure over time. By blocking this effect, eplerenone slows the structural deterioration of the heart, which is why it improves survival rather than simply relieving symptoms.
• Eplerenone binds selectively to the aldosterone receptor and has little affinity for androgen and progesterone receptors, which is why hormonal side effects are far less frequent than with spironolactone.

Interactions with other medicines

• Some medicines can affect the way Eptus Tablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
• Especially, if you are using the medicines such as ketoconazole, itraconazole (medicines to treat fungal infections), medicines used to treat HIV infection nelfinavir, ritonavir, antibiotics such as clarithromycin or telithromycin and medicines used in heart diseases such as angiotensin-converting enzyme inhibitor and an angiotensin receptor blockers.
• Ciclosporin or tacrolimus (used in the treatment of the skin conditions such as psoriasis or eczema and to prevent rejection after organ transplantation).
• Non-steroidal anti-inflammatory medicines (NSAID's) certain painkillers such as ibuprofen. These medicines may cause kidney problems and eventually increase the risk of high potassium levels in your blood.
• Trimethoprim (used to treat bacterial infections) may increase the risk of high potassium levels in your blood.
• Warfarin (medicine to prevent clotting) should be used catiously with Eptus Tablet.
• St John’s Wort (herbal medicinal products), rifampicin (used to treat bacterial infections), carbamazepine, phenytoin, and phenobarbital (used, among others, to treat epilepsy) may decrease the effect Eptus Tablet.