Diulcus Gel
Description
Diulcus Gel is a prescription topical treatment used to support the healing of diabetic foot ulcers, which are open wounds that can develop in people with diabetes due to poor blood circulation, nerve damage, and slow wound healing. These ulcers commonly appear on the feet and, if left untreated, may lead to serious complications. Diulcus Gel is applied directly to the affected area to help improve healing when used along with proper wound care and medical supervision.
Diulcus Gel is used to manage diabetic foot ulcers that do not show signs of infection. These ulcers may take a long time to heal because diabetes can affect blood flow and reduce the body's ability to repair damaged tissue. Using Diulcus Gel as part of a comprehensive treatment plan may help improve healing and support wound closure.
Diulcus Gel contains Esmolol Hydrochloride, which helps stimulate the body’s natural healing process in the affected area. When applied to the ulcer, it may support tissue repair, improve cellular activity involved in wound healing, and help the skin regenerate. This action can promote faster wound closure and help reduce the risk of complications when used together with proper wound care.
It should be used exactly as prescribed by your doctor. You should clean and dry the affected area before applying the gel and follow proper dressing instructions if advised. While it is generally well tolerated, some people may experience mild skin irritation, redness, itching, or a burning sensation at the application site. These effects are usually temporary, but if they persist or worsen, consult your doctor.
Product Summary
| Offer Price | ₹1023.75 |
| You Save | ₹341.25 (25% on MRP) |
| Contains | Esmolol(14.0 %W/W) |
| Uses | Diabetic foot ulcers |
| Side effects | Skin irritation, redness, or itching at the application site |
| Therapy | ANTI-HYPERTENSIVE |
Uses
Contraindications
- If you are allergic to any active ingredient of Diulcus Gel
- If you have had a severe reaction to similar medicines, such as beta-blockers
- If the ulcer shows signs of infection, such as pus, severe redness, or swelling
- If you have severe circulation problems in the legs or feet
- If the wound has not been properly evaluated by a healthcare professional
Side effects
- Application site irritation
- Burning sensation on the skin
- Redness at the application site
- Itching of the treated area
- Mild discomfort around the ulcer
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a diabetic foot ulcer with signs of infection.
- You have severe peripheral vascular disease.
- You have a known allergy to esmolol or similar medicines.
- You have other serious foot complications related to diabetes.
- You have not received a proper wound assessment from a healthcare professional.
- You have applied more than the recommended amount.
Directions for Use
- Clean and dry the affected ulcer area before application.
- Apply the gel only to the affected area as directed by your doctor.
- Use the amount prescribed by your healthcare provider.
- Do not apply the gel on infected wounds unless advised by a doctor.
- Wash your hands before and after applying the gel.
- Follow regular wound care instructions provided by your healthcare professional.
Storage and disposal
- Store Diulcus Gel in a cool and dry place.
- Keep it away from direct sunlight and heat.
- Keep the product out of reach of children.
- Do not use the gel after the expiry date.
Quick Tips
- Always clean the ulcer properly before applying Diulcus Gel.
- Maintain good blood sugar control to help wounds heal faster.
- Avoid walking barefoot to prevent further injury.
- Use protective footwear to reduce pressure on the affected foot.
- Follow your doctor's wound dressing instructions.
- Inspect your feet regularly for cuts, blisters, or wounds.
- Attend regular follow-up appointments to monitor healing.
Dosage
Overdose
- Applying more than the recommended amount of Diulcus Gel may increase the risk of skin irritation or discomfort.
- If you accidentally apply too much or notice unusual symptoms, consult your doctor immediately.
Missed a Dose
- If you forget to apply Diulcus Gel, apply it as soon as you remember.
- If it is almost time for your next application, skip the missed one and continue with your regular schedule.
- Do not apply extra gel to make up for the missed dose.
Mode of Action
How Does It Work?
- Diulcus Gel contains the active ingredient Esmolol Hydrochloride.
- Esmolol Hydrochloride helps stimulate the body’s natural wound-healing processes.
- It may improve cellular activity involved in tissue repair and skin regeneration.
- It supports the movement of cells that help rebuild damaged tissue.
- This helps promote faster healing and closure of diabetic foot ulcers when used with proper wound care.
Interactions
Interactions with other medicines
- Diulcus Gel may interact with certain wound care medicines or treatments.
- Inform your doctor about all medicines, supplements, or herbal products you are taking.
- Let your doctor know if you are using other topical treatments on the same area.
- Your doctor will decide whether these treatments can be used together safely.
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: What is Diulcus Gel used for?
Q: Can Diulcus Gel be used on infected wounds?
Q: How long does Diulcus Gel take to heal an ulcer?
Q: Can I stop using Diulcus Gel once the wound improves?
Q: Can I apply Diulcus Gel on healthy skin?
References
- Rastogi A, Kulkarni SA, Agarwal S, et al. Topical Esmolol Hydrochloride as a Novel Treatment for Diabetic Foot Ulcers: A Phase 3 Randomized Clinical Trial. JAMA Network Open [Internet]. [cited 12 March 2026].
- Kulkarni S, Deshpande P, Rastogi A. Novel topical esmolol hydrochloride improves wound healing in diabetes by inhibiting aldose reductase and facilitating fibroblast migration. PubMed [Internet].[cited 12 March 2026].
- Rastogi A, Kulkarni SA, Agarwal S, et al. Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers: A Phase 3 Randomized Clinical Trial. PubMed [Internet]. [cited 12 March 2026].
- National Cancer Institute. Esmolol Drug Dictionary. NCI Drug Dictionary [Internet]. [cited 12 March 2026].
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