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Molecule Description

Xylometazoline belongs to the decongestant and alpha-adrenergic class of medicines that are used to treat the symptoms of nasal congestion.

Uses of Xylometazoline

  • Nasal congestion (blocked nose)
  • Allergic rhinitis (swelling of the lining of the nasal cavity)
  • Sinusitis (swelling of the cavities of the face)

Contraindications of Xylometazoline

When should one not use Xylometazoline

  • Allergic to Xylometazoline and similar nasal decongestants
  • Recent history of any neurosurgery

Side effects of Xylometazoline

Common side effects of this drug are:

  • Increase in nasal discharge
  • Temporary burning at site or local irritation
  • Sneezing
  • Temporary visual disturbances
  • Headache

Precautions and Warnings of Xylometazoline


Can I take Xylometazoline during pregnancy?
No more information is available about its safety in pregnancy. Hence do not take this medicine unless considered essential by your physician.

Breast Feeding

Can I take Xylometazoline while breastfeeding?
It is unknown whether Xylometazoline can pass into breast milk. You should not take this medicine if you are breastfeeding.


Can I drive if I have consumed Xylometazoline?
It has no effects on the ability to drive.


Can I consume alcohol with Xylometazoline?
Interaction of Xylometazoline with alcohol is unknown. Hence, it is advisable to discuss with your doctor before you drink alcohol.

Other General Warnings

Talk to your doctor if
  • You have had any surgery related to nose or neurosurgery
  • Have high blood pressure
  • Thyroid problems (hyperthyroidism)
  • Glaucoma
  • Heart diseases
  • Diabetes

Mode of Action of Xylometazoline

How Does It Work?

Xylometazoline acts by shrinking the dilated blood vessel in the nasal passage that causes nasal congestion.

Interactions of Xylometazoline

Interactions with other medicines

Xylometazoline is taken as nasal drops or spray and there is no chance of interaction with any other medicine. But many medicines can interact, which includes anti-depressants such as Phenelzine, Oxytocin, appetite suppressing medicines, Ergotamine and Methysergide. Tell your doctor if you are taking any over the counter medicines or herbal products or vitamins.
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Interactions with food items

No interactions with food are reported.

Dietary Restrictions of Xylometazoline

No information is available on dietary restrictions while you are taking Xylometazoline when taken with food. Consult your doctor or pharmacist for further details.

Dosage of Xylometazoline


The symptoms of overdose are extreme tiredness, sweating, dizziness, slow heartbeat and coma. Immediately seek emergency medical care if you suspect an overdose.

Missed a Dose

If you have missed a dose, then take the next dose as soon as possible. However, if it is the time for the next dose, then skip the dose and start with the next dose. Do not take a double dose as excessive doses may cause congestion to get worse.
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Content Details


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should be discussed with my healthcare provider before taking this medicine?

A: You should not use this medicine if you are allergic to it or any other nasal sprays. Give a detailed account of all your medical and surgical history and show all your previous and recent blood reports to your doctor. Also, tell your doctor about all the ongoing medicines, herbal medicines or nutritional supplements that you may be taking before starting this treatment.

Q: What precautions should I consider before taking this medicine?

A: Do not use this medicine for more than prescribed dose and should be used with extreme caution in children below 12 years of age.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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