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Trazodone

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Molecule Description

Trazodone is an antidepressant and anxiety-relieving medicine.

Uses

  • Depression
  • Anxiety

Contraindications

When should one not use Trazodone

  • Over-sensitivity to the medicine
  • Recent heart attack
  • Alcohol intoxication

Side effects

Common side effects of this drug are:

  • Blurred vision
  • Confusion
  • Dizziness
  • Faintness or light headache
  • Sweating
  • Unusual tiredness
  • Feeling less alert than usual
  • Loss of appetite and weight loss
  • Sweating more than usual
  • Skin rash
  • Itching
  • Chest pain
  • Difficulty with speaking
  • Liver disorders such as hepatitis
  • Decreased sex drive
  • Dry mouth, altered taste
  • Higher than average number of white blood cells (seen by a blood test)
  • Nightmares
  • High blood pressure
  • High temperature
  • Flu type symptoms
  • Suicidal intentions

Precautions and Warnings

Pregnancy

Pregnancy

You should not take this medicine during pregnancy. It is because the safety of this medicine for use during pregnancy has not been established.

Breast Feeding

Breast Feeding

It is probably unsafe to take this medicine if you are breastfeeding or plan to breastfeed as it is unknown whether this medicine passes into breast milk. Seek doctor’s advice.

Driving

Driving

Do not drive when taking this medicine.

Alcohol

Alcohol

It is unsafe to drink alcohol with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • Follow your doctor’s prescription strictly. Do not alter or miss any dose of this medicine. Stopping this medicine abruptly may cause serious problems
  • Keep away from children’s reach
  • Tell your doctor if:
  • You are under 18 years of age
  • Other medical issues those may affect the use of this medicine
  • Have heart problems
  • Bleeding or blood clotting disorder
  • Seizures or epilepsy
  • Narrow-angle glaucoma
  • Bipolar disorder (manic depression)
  • History of suicidal attempts
  • Have abnormally low levels of potassium (hypokalaemia), calcium (hypocalcaemia) or magnesium (hypomagnesaemia) in your blood
  • Have difficulties in passing urine or a reduced stream of urine
  • Have liver problems

Mode of Action

How Does It Work?

Depression occurs due to the imbalance of certain chemicals in the brain. This medicine regulates the imbalance of chemical neurotransmitters present in the brain and thus cures depression. Its anti-Serotonin property makes it effective in treating anxiety.

Interactions

Interactions with other medicines

  • Zolpidem
  • Lorazepam
  • Citalopram
  • Cyclobenzaprine
  • Furosemide
  • Escitalopram
  • Carbamazepine
  • Digoxin
  • Phenytoin
  • Do not take this medicine within 14 days of taking a Monoamine Oxidase inhibitor, e.g., Linezolid, Isocarboxazid, etc.

Interactions with food items

Cheese and preserved food.

Dietary Restrictions

Do not consume cheese or packed food when taking this medicine.

Dosage

Overdose

Inform your doctor immediately in case of an overdose of Trazodone. It can be fatal when it is taken with alcohol, barbiturates or sedatives such as Diazepam (Valium).

Missed a Dose

If you missed any dose, take it as early as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compensate for a missed one.

Frequently Asked Questions (FAQs)

Tell your doctor if you have:Liver or kidney diseaseHeart diseaseA bleeding or blood clotting disorderSeizures or epilepsyNarrow-angle glaucomaBipolar disorder (manic depression)A history of long qt syndromeA history of drug abuse or any suicidal thoughtsIf you have recently had a heart attack

Trazodone should be taken after a meal with a glass of water. Swallow the tablet as a whole, do not crush or chew it.

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