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Silodosin+Dutasteride

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Molecule Summary

Uses
Benign prostatic hyperplasia (BPH)
Therapy
Drugs For Benign Prostatic Hyperplasia
Side Effects
Abnormal ejaculation, diarrhoea, runny or blocked nose, dizziness
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Molecule Description

Silodosin+Dutasteride is used to manage benign prostatic hypertrophy (BPH, also called benign prostatic hyperplasia). It is a common condition in older men with an enlargement of the prostate gland. The prostate gland is a part of the male reproductive system and is located below the bladder. Common symptoms of benign prostatic hypertrophy include incomplete emptying of the bladder, trouble passing urine, frequent need to pass urine and a weak urine flow. Silodosin+Dutasteride contains a combination of silodosin and dutasteride as its main components. It works by relaxing the bladder muscles and shrinking the enlarged prostate, which helps to relieve the symptoms of benign prostatic hypertrophy. This medicine is not meant to be used to treat prostate cancer. Take Silodosin+Dutasteride in the exact dose and duration as prescribed. Do not stop taking this medicine on your own. Before starting treatment with this medicine, inform the doctor about your detailed medical history.

Uses

Silodosin+Dutasteride is used in men for the management of enlarged prostate gland (benign prostatic hyperplasia).

Contraindications

When should one not use Silodosin+Dutasteride

  • If you are allergic to silodosin, dutasteride, or any other ingredient of Silodosin+Dutasteride.
  • If you are taking medicines like ketoconazole, itraconazole, ritonavir, or cyclosporine. If you are not sure what these medicines are, please confirm with your doctor.
  • If you have severe liver or severe kidney disorders.
  • If you are a female or a child.

Side effects

Common side effects of this drug are:

  • Abnormal ejaculation
  • Diarrhoea
  • Runny or blocked nose
  • Dizziness

Precautions and Warnings

Pregnancy

Pregnancy

Silodosin+Dutasteride is indicated for use in men only.

Breast Feeding

Breast Feeding

Silodosin+Dutasteride is indicated for use in men only.

Driving

Driving

Silodosin+Dutasteride may cause dizziness. If you experience any such effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

Alcohol

There is limited information on the interaction of alcohol with Silodosin+Dutasteride. Ask your doctor for advice on the use of alcohol with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You suffer from low or high blood pressure.
  • You suffer from any eye disorder or are planning to get eye surgery.
  • You suffer from heart disease.
  • You have any fungal or viral infection.
  • You are taking medicines that lower immunity.
  • You have liver or kidney problems.

Mode of Action

How Does It Work?

  • Silodosin+Dutasteride contains a combination of silodosin and dutasteride as active ingredients.
  • Silodosin works by relaxing the muscles in the prostate, bladder, and urethra (the tube that carries urine outside the body).
  • Dutasteride helps in reducing the size of the enlarged prostate.
  • Together, this allows the proper flow of urine and helps to relieve the symptoms of benign prostatic hypertrophy.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Silodosin+Dutasteride works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
  • Antifungal medicines such as ketoconazole, itraconazole, immunosuppressant medicine such as cyclosporine, and antiviral medicine such as ritonavir should be avoided with Silodosin+Dutasteride.
  • Concomitant use of blood pressure-lowering medicines should be done with caution, as it may lead to excessive lowering of blood pressure.

Interactions with food items

Taking Silodosin+Dutasteride with food is recommended to minimize gastrointestinal discomfort and improve absorption. It is advisable to avoid grapefruit and grapefruit juice.

Dosage

Overdose

If you have taken too much of Silodosin+Dutasteride, contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

  • If you forget a dose of Silodosin+Dutasteride, take it as soon as you remember it.
  • However, if it is nearly time for the next dose, skip the missed dose.
  • Do not take a double dose to make up for a forgotten dose.

Frequently Asked Questions (FAQs)

You should take Silodosin+Dutasteride for as long as the doctor has prescribed it. Do not stop taking this medicine on your own.

Silodosin+Dutasteride should be taken exactly as directed by your doctor. Take it with a glass of water. Do not cut, break or chew the medicine. It would be best if you took it at a fixed time for optimal results. You should not consume more than the dose prescribed by your doctor.

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