Prulifloxacin

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Molecule Description

Prulifloxacin belongs to a group of Fluoroquinolones, which is an antibiotic that acts on bacteria. It prevents the multiplication of bacteria and leads to bacterial cell death, thereby prevents the infection.

Uses

Acute uncomplicated lower urinary tract infections (simple cystitis)
Complicated lower urinary tract infections
Lower respiratory tract infections
Acute exacerbation of chronic bronchitis
Gastroenteritis, including infectious diarrhea

Contraindications

When should one not use Prulifloxacin

Patients with tendon diseases related to the administration of Quinolones
Hypersensitivity to Prulifloxacin, any member of the Quinolone class of antimicrobial agents
Celiac disease
Epilepsy or other seizure disorders
Depression and anxiety disorders

Side effects

Common side effects of this drug are:

Allergic reaction
Epigastric pain
Gastritis
Diarrhea
Dizziness
Sleep disturbances
Muscle spasm
Photosensitivity of skin
Hearing impairment
Fever
Decreased appetite
Nausea and vomiting

Precautions and Warnings

Pregnancy

It should not be used in pregnant women or if you are planning for pregnancy. Make sure that you check with your doctor if you are pregnant or planning a pregnancy.

Breast Feeding

It must be used by breastfeeding mothers only if it is necessary.

Driving

You shouldn’t drive or operate heavy machinery when under the influence of the medicine as it induces drowsiness and dizziness.

Alcohol

No research indicates that it may be harmful if taken with alcohol. Make sure that you consult with your doctor before you take medicine under the influence of alcohol.

Other General Warnings

Talk to your doctor if

Drug resistance
Exposure to the sun or UV rays may cause phototoxicity reactions
Patients with latent or known deficiencies for the Glucose-6-Phosphate-Dehydrogenase activity are predisposed to hemolytic reactions
Used carefully in older people because it has a higher risk of tendon rupture and tendonitis

Mode of Action

How Does It Work?

Fluoroquinolones stops the replication, repair, recombination and transcription of bacterial DNA; it does this by inhibiting bacterial DNA gyrase. Bacteria get eradicated due to this mechanism.

Interactions

Interactions with other medicines

Warfarin
Antacids containing calcium/ magnesium/ aluminium
Theophylline
Cimetidine
Probenecid
Hypoglycemic agents
Nicardipine

Interactions with food items

It may interact with dairy products rendering the medicine ineffective, so they must not be eaten in excess.

Dietary Restrictions

You must ensure that you don’t consume a lot of dairy products, juices or any calcium-fortified products.

Dosage

Overdose

Get medical treatment immediately or visit the doctor in case of taking an overdose. You must make the person vomit to empty the stomach, if he has overdosed on the medicine.

Missed a Dose

If you missed any dose, take it as soon as you remember. If it comes close to the next dose, then you can take that dose and skip the missed dose altogether. Never double the dose.

Frequently Asked Questions (FAQs)

It is not recommended to take medicine with dairy products like curd or milk or with calcium-fortified juices. They can be consumed as a part of a usual meal but make sure that you don’t take them when you are taking the drug. This is because the medication may be rendered ineffective by it.

No research proves that this medicine is addictive.

This medicine acts on bacteria and does not affect virus, so it should not be used in viral infections.

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