Cyclobenzaprine
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Molecule Summary
| Uses | Muscle Pain, Spasm |
| Therapy | Muscle Relaxant |
| Side Effects | Dizziness, Dry Mouth, Drowsiness |
Assurance
available
Regulated
Molecule Description
Cyclobenzaprine is used for short term relief from muscle pain and stiffness, most commonly following an injury. It belongs to a class of medicines known as ‘muscle relaxants.’
Uses
Relief from muscle pain, stiffness or tightness, limitation of movements, usually following an injury or strenuous activity.
Contraindications
When should one not use Cyclobenzaprine
- Allergy to Cyclobenzaprine or any components of this medicine
- A specific class of antidepressants called Mono Amine Oxidase (MAO) inhibitors (e.g., Selegiline, Rasagiline, Phenelzine, etc.) or tricyclic antidepressants (Amitriptyline, Imipramine, Amoxapine)
- Recent heart disease (heart attacks, irregular heartbeats, rhythm diseases, reduced pumping efficiency of the heart)
- Kidney diseases
- Thyroid problems
Side effects
Common side effects of this drug are:
- Headache, dizziness, dry mouth, fatigue, sleepiness
- Feeling sick (nausea), indigestion (dyspepsia), constipation
- Taste, vision and attention disturbances
- Tremors, pounding of heart (palpitations), acne (pimples)
- Irregular and fast heartbeats, abnormal heart rhythm, allergic reactions, rashes, mood changes, nervousness, depression, sweating, ringing in the ears, weight loss, stomach upset, gas, liver problems, sweating, urinary problems (uncommon)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Inform the doctor if any of the following applies to you:
- Elderly patients
- Any depressive or psychotic disorder for which treatment is being taken
- If you are suffering from urinary retention (incomplete emptying of the bladder) or increased pressure in the eye (glaucoma) and are seeking treatment
- Avoid taking Cyclobenzaprine if you have liver disease
Mode of Action
How Does It Work?
Cyclobenzaprine acts on the brain and spinal cord and regulates the effects of the nerves on the muscle and thus causes relaxation and pain relief. It is also thought to block the pain impulses from reaching the brain.
Interactions
Interactions with other medicines
- Antidepressant medicines (to treat depression) like Selegiline, Rasagiline, Phenelzine, Amitriptyline, Imipramine, Amoxapine, Doxepin, Nortriptyline, etc.
- Inform the doctor about all the medicines you are using (including prescription medicines, non-prescription medicines, and herbal products)
Interactions with food items
Alcohol consumption should be avoided, no other food interactions are observed.
Dosage
Overdose
Unintentional overdose of Cyclobenzaprine may not be harmful. But consult the doctor in the presence of symptoms such as drowsiness, or fast heartbeats (tachycardia).
Missed a Dose
If you have missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dose schedule. Do not take a higher or a double dose to make up for the missed dose.
Frequently Asked Questions (FAQs)
Articles
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References:
- Webmd. Cyclobenzaprine. [accessed on 8 Jun 2026] (Online)
- Mayoclinic. Cyclobenzaprine. [accessed on 8 Jun 2026] (Online)
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Cyclobenzaprine. [Updated 2019 Jul 20].
- Cyclobenzaprine, DailyMed [accessed on 8 Jun, 2026] (Online)
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