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Aceclofenac+Paracetamol / Acetaminophen

Molecule Description

Aceclofenac+paracetamol is a combination medicine. It is a pain-relieving medic

ine used for relieving pain, swelling and inflammation in adults. Aceclofenac and paracetamol both work by interfering with the action of certain chemicals responsible for pain, swelling and inflammation. Aceclofenac+paracetamol is available in form of tablets, capsules, syrup and suspension.


Uses of Aceclofenac+Paracetamol / Acetaminophen

For relieving pain, inflammation and swelling in various forms of arthritis. It is also useful in gynaecological pain, dental pain, low backache, pain and swelling in the ear, nose and throat.

Contraindications of Aceclofenac+Paracetamol / Acetaminophen

When should one not use Aceclofenac+Paracetamol / Acetaminophen

If you are allergic to paracetamol and aceclofenac. If you have a history of ulcer or bleeding in the stomach or any part of your digestive tract. If you have experienced an allergic reaction due ...
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Side effects of Aceclofenac+Paracetamol / Acetaminophen

Common side effects of this drug are:

  • Dizziness
  • Drowsiness
  • Dyspepsia
  • Abdominal pain
  • Nausea
  • Diarrhoea

Precautions and Warnings of Aceclofenac+Paracetamol / Acetaminophen



Can I take Aceclofenac+Paracetamol / Acetaminophen during pregnancy?
Aceclofenac+paracetamol should not be used during pregnancy especially in third trimester.

Breast Feeding

Can I take Aceclofenac+Paracetamol / Acetaminophen while breastfeeding?
Aceclofenac+paracetamol should not be used by a lactating woman unless considered essential by the treating doctor.


Can I drive if I have consumed Aceclofenac+Paracetamol / Acetaminophen?
Long term treatment with this combination may cause dizziness. Driving or operating machinery is to be avoided.


Can I consume alcohol with Aceclofenac+Paracetamol / Acetaminophen?
Although there is no known interaction with alcohol and aceclofenac+paracetamol, it is essential to consult your physician if you have a habit of regular drinking. Consuming alcohol while taking pain killers is known to increase the risk of bleeding, ulcer and perforation in stomach and intestine (upper gastrointestinal tract).

Other General Warnings

Talk to your doctor if
  • You have a kidney or liver problem or blood clotting disorder.
  • You have a bleeding problem in the stomach, ulcers in the intestine (perforation) or Crohn's disease.
  • You have asthma, as this medicine can worsen the symptoms of asthma.
  • You have an autoimmune disease called systemic lupus erythematosus.
  • You are an alcoholic, as concomitant use of this medicine can affect the liver.
  • You experience skin rashes & lesions after taking this combination.
  • You are an elderly patient or taking water pills or have kidney disorders; this medicine can affect the risk of kidney failure. Your doctor may ask you to do renal function tests for the same.

Mode of Action of Aceclofenac+Paracetamol / Acetaminophen

How Does It Work?

Paracetamol works by interfering with the formation of an inflammatory mediator prostaglandin. Prostaglandin is responsible for pain and swelling. Aceclofenac acts by inhibiting certain enzymes res...
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Interactions of Aceclofenac+Paracetamol / Acetaminophen

Interactions with other medicines

  • Some medicines affect the way aceclofenac+paracetamol works or this combination itself reduces the effectiveness of other medicines taken at the same time.
  • Inform the doctor about the medicines, supplements, or herbals you are taking or might take to avoid possible interaction.
  • Especially if you are taking medicines for a heart condition, steroids, blood pressure-lowering medicines, certain antibiotics, immunomodulators, blood thinners, antidiabetics, mifepristone and medic...
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  • Avoid concomitant use of other pain-relieving medicines while taking this combination.

Dosage of Aceclofenac+Paracetamol / Acetaminophen


An overdose of medicine containing aceclofenac+paracetamol may cause headache, nausea, vomiting, stomach pain, diarrhoea, dizziness. Seek immediate medical help.

Missed a Dose

Take the missed dose as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.

Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Is there any risk associated with the use of Aceclofenac+Paracetamol / Acetaminophen?

A: Use of pain killers may be associated with risk of conditions related to heart, bledding and ulcer in digestive tract. The risk may be more when this medicine is used for prolonged duration and in people with existing heart condition and with risk factor of getting such condition.

Q: Can Aceclofenac+Paracetamol / Acetaminophen cause liver related probelm?

A: If this combination is taken in more than recommended dose it can affect your liver. The chances of getting liver related problem is more common in people who drink everyday more than 3 alcoholic drinks and are taking other medicines containing paracetamol.
Last Updated on: 14 Oct 2021 | 10:38 AM (IST)

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