Zerodol-P Tablet
10 Tablet(s) in StripProduct Summary
Zerodol P Tablet contains aceclofenac 100 mg and paracetamol 325 mg, and is used to treat pain and inflammation associated with arthritis or spondylitis, as well as muscle and joint pain, low back pain and toothache; Ipca Laboratories manufactures it. The ingredients reduce chemical messengers causing pain, inflammation and fever.
Medically Reviewed by Dr. Ambika Dashrathrao Mamde
Last updated on: 13 October 2026 | 7:45 PM (IST)
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Dose Form
TABLET
Expiry
General Information
| Therapy | Analgesic/antipyretic |
| Composition | Aceclofenac(100.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) Aceclofenac 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg |
Aceclofenac 100.0 Mg+Paracetamol / Acetaminophen 325.0 Mg

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*Offer applicable on orders above ₹1000About Zerodol
Zerodol P Tablet is a medicine that helps reduce pain, swelling, and inflammation in various conditions. It is primarily used to relieve mild-to-moderate pain, swelling, and inflammation, as well as fever, associated with joint and muscle conditions, arthritis, toothache, and postoperative discomfort.
It contains aceclofenac and paracetamol. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the enzyme responsible for pain and swelling. Paracetamol is an analgesic and antipyretic that reduces mild to moderate pain and minor febrile (fever) conditions. Together, they reduce inflammation and control pain more effectively than either ingredient alone.
Other tablets with a similar combination include Aceclo Plus, Acenac P, Aldigesic P, and Acemiz Plus.
Take Zerodol P exactly as your doctor prescribes. To avoid stomach upset, always take it after food with a full glass of water. Never take more than the recommended daily dose, even if your pain is severe. If you miss a dose, take it as soon as you remember, but don’t double up.
Avoid drinking alcohol while taking Zerodol P, as it may increase the risk of liver damage. This medicine contains paracetamol; hence, avoid taking other medications that contain paracetamol. It’s safe. Inform your doctor if you are pregnant, trying to conceive, or breastfeeding. It’s also important to share your complete medical history, including any liver, kidney, gut, or heart problems, for safe and effective treatment.
Uses
- Rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
- Muscle pain, back pain, and dental pain.
- Ear, nose, and throat pain.
Contraindications
- If you are allergic to aceclofenac, paracetamol or any of the ingredients of Zerodol P tablet.
- If you have a history of asthma, skin rashes, swelling & nasal congestion after taking other painkillers.
- If you have a history of or currently have stomach ulcers or bleeding in any part of the digestive tract.
- If you have any cardiovascular disease, like heart failure, high blood pressure, or a liver or kidney-related problem.
- If you are pregnant, this medicine should not be taken throughout pregnancy.
Side effects
- Nausea
- Stomach pain
- Diarrhoea
- Indigestion
- Dizziness
- Excess sleepiness
Precautions and Warnings
Alcohol
WITH CAUTIONIt is advisable to avoid the consumption of alcohol during the treatment with the Zerodol P Tablet as it may worsen your liver problems. Contact your doctor or pharmacist for further information.
Pregnancy
UNSAFEZerodol P tablet should not be used during pregnancy. It can also delay labour and cause bleeding defects in pregnant women. Consult your doctor for further information on the use of this medicine during pregnancy.
Breastfeeding
WITH CAUTIONIt is advisable to avoid taking Zerodol P tablet while breastfeeding, as its components may pass in breast milk and produce undesirable effects in the breastfed baby.
Driving
WITH CAUTIONZerodol P tablet may make you feel dizzy, you should avoid driving if you do not feel well or are unable to be alert.
Other General Warnings
- You have a kidney or liver problem or a blood-clotting disorder.
- You have a stomach bleeding problem, ulcers in the intestine (perforation), or Crohn's disease.
- You have asthma, as the Zerodol P tablet can worsen the symptoms of asthma.
- You have an autoimmune disease called systemic lupus erythematosus.
- You are an alcoholic, as concomitant use of this medicine can damage the liver.
- You experience skin rashes & lesions after taking the Zerodol P tablet.
- You are elderly, taking water pills, or have kidney disorders, this medicine can increase the risk of kidney failure. Your doctor may ask you to do renal function tests.
Doctor’s suggestion

Directions for use
Storage and disposal
- Store Zerodol P tablets in a cool and dry place and away from light.
- Keep it away from children and pets.
Quick tips
- Zerodol P is an NSAID used to relieve pain and inflammation. It treats arthritis, spondylitis, low back pain, toothache, headache, and pain/swelling in the ear, nose, and throat.
- Zerodol P tablet may cause stomach upset, nausea, and vomiting as a side effect. It is important to take only the prescribed dosage of this medication daily, as it contains paracetamol which can be harmful to the liver or kidney if taken in excess.
- Before taking this medicine, inform your doctor about all your medications and medical history.
- Take Zerodol P tablet with food to avoid stomach upset or nausea.
- Zerodol P should be used with caution in people with kidney-related conditions and liver diseases.
Dosage
Overdose
Missed a dose
How Zerodol works
- Zerodol P tablet works by the combined action of both its components: aceclofenac and paracetamol.
- Aceclofenac works by interfering with the production of a chemical called prostaglandins, which is responsible for swelling and pain.
- Paracetamol works by reducing the level of the sensation of pain.
Interactions
Drug interactions of Zerodol with other medicine salt
Food interactions
Frequently asked questions
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Substitutes for Zerodol
References
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 4 August 2022]
- Aceclofenac 100 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. 2024 [cited 20 December 2024].
- Paracetamol 500mg Tablets - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. 2024 [cited 20 December 2024].
- Acetaminophen. (n.d.). Medlineplus.Gov.2024 [cited 20 December 2024].
- PubChem. (n.d.). Aceclofenac. Nih.Gov. 2026 [cited 18 May 2026].
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