Melacare Cream
25g Cream in Tube
Product Summary
Melacare Cream is a topical combination medicine used to treat moderate to severe facial melasma, a condition causing dark patches on the face. Made by Ajanta Pharma, it contains hydroquinone 2% w/w, mometasone furoate 0.1% w/w and tretinoin 0.025% w/w. These reduce melanin production, increase skin-cell renewal and decrease inflammation.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 3:11 PM (IST)
Save 39% with Trusted Branded Substitutes ➜ Made by
AJANTA PHARMA LIMITED
Dose Form
CREAM
Expiry
General Information
| Therapy | Drugs for melasma |
| Composition | Hydroquinone(2.0 %W/W)+Mometasone Furoate(0.1 %W/W)+Tretinoin(0.025 %W/W) Hydroquinone 2.0 %W/W+Mometasone Furoate 0.1 %W/W+Tretinoin 0.025 %W/W |
Hydroquinone 2.0 %W/W+Mometasone Furoate 0.1 %W/W+Tretinoin 0.025 %W/W
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*Offer applicable on orders above ₹1000About Melacare
Melacare Cream is a prescription medication used to treat melasma, a skin condition that causes brown or dark patches on the face. It works by combining three active ingredients: hydroquinone, which helps lighten dark spots; mometasone, which reduces inflammation; and tretinoin, which promotes skin cell turnover for a smoother complexion.
This cream should be applied exactly as prescribed by your doctor, usually in a thin layer on affected areas. Avoid contact with your eyes, mouth, and genital areas, and always wash your hands after application. Using it more frequently than prescribed does not speed up results and may increase the risk of side effects.
Common side effects may include skin irritation, redness, burning, or dryness. These effects usually subside with time, but if they worsen or persist, consult your doctor immediately. People with sensitive skin or underlying skin conditions should inform their doctor before starting this cream.
Always use sunscreen and protective clothing while using Melacare Cream, as sun exposure can worsen melasma and reduce the effectiveness of the treatment. Avoid applying the cream immediately before sun exposure or tanning, and do not use it on broken or infected skin.
Other medications containing the same combination of ingredients include Skinlite cream, No Scar cream, Skinshine cream, Hhlite cream, and Melamet cream. In case the cream accidentally comes into contact with the eyes, rinse the eyes thoroughly with water and seek medical advice if irritation continues.
Uses
Contraindications
- If you are allergic to mometasone, tretinoin, hydroquinone or any of the ingredients of the Melacare cream.
- If you have skin conditions such as eczema (infected skin due to allergy), rosacea (small red pustules on face), rashes around the mouth (perioral dermatitis) or damaged skin anywhere in the body.
- If you have a viral or fungal infection of the skin, any ulcers on the skin or tuberculosis.
- If you need to be exposed to the sun for prolonged periods (using sunscreen lotion is advisable).
- If you have a skin tumour or a family history of skin tumour.
Side effects
- Itching, redness, burning, irritation, thinning of the skin.
- Skin sensitivity at the site of application.
Precautions and Warnings
Alcohol
WITH CAUTIONIt is unknown if components of this medicine interact with alcohol. However, you should avoid using alcohol as it can delay the body's response to infection.
Pregnancy
WITH CAUTIONAs there is limited information available about the effect of Melacare cream during pregnancy, thus it is recommended to avoid using this cream during pregnancy unless advised by your doctor.
Breastfeeding
UNSAFEIt is unknown if the components of this medicine pass into the breastmilk and there are no establishments of its safety in breastfeeding women. Thus, it is not recommended to use if you are breastfeeding.
Driving
SAFEMelacare cream is unlikely to affect the ability to drive and operate machinery.
Other General Warnings
- You have a history of allergic reactions after the application of topical creams.
- You are pregnant or are breastfeeding.
- You think rashes or infections have developed on the skin after using this medicine.
- Avoid contact with the eyes, mouth or nose. If it occurs wipe or wash it off immediately.
- You should avoid being exposed to direct sunlight, after applying this cream, to reduce the chances of photosensitization (which means skin damage due to UV or sunlight). Try to use good sunscreen with at least SPF 15 and full clothes to avoid exposure.
Directions for use
- Use this medicine as directed by your doctor.
- Apply it on a healthy skin surface. Avoid applying on cuts and wounds.
- Wash your hands before and after using this medicine unless your hands are the area to be treated.
- In case your eyes come in contact with this cream, then rinse your eyes with clean water immediately.
Storage and disposal
- Store this medicine in the original container in a clean and dry place, protected from moisture, sunlight and heat.
- Keep the medicine away from children and pets.
- Do not freeze.
Quick tips
- Melacare cream is used to help in the treatment of melasma/hyperpigmentation of the skin. It also helps lighten skin tone or appearance and dark spots or age spots in older people due to exposure to the sun.
- Do not use more than the recommended amount of this medicine or do not use it for longer periods of time than directed.
- Before starting Melacare cream, inform your doctor if you are pregnant, planning on becoming pregnant or breastfeeding. Also, inform your doctor about all other medicines that you are using and your complete medical history.
- Avoid exposure to sun rays after applying Melacare cream. Do not apply to open wounds or weeping areas.
- Inform your doctor if you have a skin tumour or a family history of skin tumours.
Dosage
Overdose
Missed a dose
How Melacare works
- Hydroquinone inhibits an enzyme known as tyrosinase, which is responsible for the production of a pigment called melanin. Melanin is responsible for skin pigmentation and melasma.
- Tretinoin is a metabolite of vitamin A and is keratolytic. It is responsible for the elimination of melanin that has been formed. It also has anti-inflammatory properties.
- Mometasone is a corticosteroid and it works by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes. Mometasone narrows and constricts blood vessels, which are dilated (widened) and leaky and allowing other inflammatory cells into the skin to promote the inflammatory response.
Interactions
Interactions with other medicines
- Since this medicine is to be used externally on the skin, it is less likely to interact with other medicines. However, always consult your doctor if you are taking other medicines for treating other health conditions.
- You should always tell the doctor if you are taking any other medicines, herbal preparation or supplements to avoid any interaction with Melacare cream.
Food interactions
Frequently asked questions
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References
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 11 January 2022]
- Lookbrite [Internet]. Torrentian.com. 2022 [cited 11 January 2022]
- Drugs H. Tretinoin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 11 January 2022]
- Drugs H. Mometasone Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [cited 11 January 2022]
- Hydroquinone Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD [Internet]. Webmd.com. 2022 [cited 11 January 2022]
- Schwartz C, Jan A, Zito PM. Hydroquinone. [Updated 2023 Aug 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan- [Accessed 26 Dec. 2024].
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 441336, Mometasone Furoate. Retrieved December 26, 2024
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