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Combiflam Tablet

20 Tablet(s) in Strip
By SANOFI
Salt: Ibuprofen 400.0 Mg+Paracetamol / Acetaminophen 325.0 Mg
MRP ₹57.45
₹41.94 27% OFF
₹2.1/Tablet (Inclusive of all taxes)
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✱Offer applicable on order above ₹1000
Combiflam Strip Of 20 Tablets

Product Summary

Combiflam Tablet is used to treat headache, toothache, body ache, muscle and joint pain, and fever; Sanofi combines ibuprofen 400 mg with paracetamol 325 mg in this medicine. Both ingredients reduce chemicals involved in pain and fever. Ibuprofen also reduces inflammation through its anti-inflammatory action.

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General Information

Therapy		 Analgesic/antipyretic
Composition		 Ibuprofen(400.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) Ibuprofen 400.0 Mg+Paracetamol / Acetaminophen 325.0 Mg
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Ibuprofen 400.0 Mg+Paracetamol / Acetaminophen 325.0 Mg

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About Combiflam

Combiflam tablet is a commonly used painkiller medication that helps treat various conditions, including headaches, toothaches, body aches, muscle pain, joint pain, and fever. The active ingredients in Combiflam are Ibuprofen and paracetamol. Combiflam works by blocking the release of certain chemical messengers that cause pain, fever, and inflammation (redness and swelling).

It is recommended to take the tablet with or after food to minimise gastric irritation, especially in individuals with sensitive stomachs. Overuse or self-medication without medical supervision is discouraged due to the potential for gastrointestinal bleeding, liver toxicity, and renal complications, particularly in individuals with pre-existing conditions. You should avoid taking additional paracetamol-containing products while on Combiflam to reduce the risk of liver injury. It's essential to adhere to the prescribed dose and not skip any dose.

Before taking it, tell your doctor if you consume a lot of alcohol, use blood thinners, have asthma, or have liver or kidney problems; the dose or suitability of this medicine may be compromised. It is not recommended for children under 12. Special caution should be exercised in the elderly or individuals with conditions like asthma, high blood pressure, heart failure, or autoimmune diseases. Though generally well tolerated, side effects may include nausea, dizziness, vomiting, skin rashes, and in rare cases, serious allergic reactions or gastrointestinal bleeding.

Women who are pregnant or breastfeeding should consult their doctor before using it. Inform your doctor about all other medications you are taking because they may interact with it.

Some other tablets containing ibuprofen and paracetamol are Ibugesic Plus and Flexon tablet.

Uses

Combiflam Tablet is used to relieve headache, toothache, body aches, muscle & joint pain, and reduce fever.

Doctor’s suggestion

Dr. Parth Mehta
Dr. Parth Mehta MBBS, DNB (Orthopaedics) ★★★★★
Combiflam contains ibuprofen and paracetamol and is used for the symptomatic relief of fever and mild to moderate pain. It should be used according to the recommended dose and under appropriate medical guidance, particularly in children. Parents and caregivers should consult a healthcare professional before administering combination pain-relief medicines to children.

Contraindications

  • If you are allergic to ibuprofen, paracetamol or any other ingredients of Combiflam Tablet.
  • If you have a history of an allergic reaction due to painkillers like aspirin, etc.
  • If you are taking medicines containing paracetamol, ibuprofen, or other pain medicines.
  • If you have a history of ulcers or bleeding in the digestive tract.
  • If you have an active clotting disorder or disorders related to the blood supply to the brain.
  • If you are experiencing a fluid loss (due to vomiting, diarrhoea, or not drinking enough fluids).
  • If you have kidney or liver function problems.
  • If you are pregnant (last trimester), it should not be given to children under 12 years of age (<40kgs).

Side effects

  • Stomach upset
  • Diarrhoea
  • Vomiting
  • Dizziness
  • Skin rashes
  • Itching

Doctor’s suggestion

Dr. Vishesh Bharucha
Dr. Vishesh Bharucha MBBS, MD Medicine ★★★★★
Patients should immediately seek medical attention if they develop black stools, vomiting of blood, severe abdominal pain, or reduced urine output, as these may indicate serious digestive or kidney-related complications.

Precautions and Warnings

Alcohol

Alcohol

WITH CAUTION

Avoid consuming alcohol along with Combiflam Tablet.

Pregnancy

Pregnancy

UNSAFE

Combiflam Tablet is not recommended during pregnancy. Always inform your doctor if you are pregnant or plan to become pregnant, and take the Combiflam Tablet under medical supervision if required.

Breast feeding

Breastfeeding

UNSAFE

Combiflam Tablet is not recommended for breastfeeding women. Always inform your doctor if you are breastfeeding your child and take this medicine under medical supervision if required.

Driving

Driving

WITH CAUTION

If you experience dizziness, drowsiness, fatigue and visual disturbances after taking this medicine, avoid driving.

General warnings

Other General Warnings

Talk to your doctor if
  • You are an elderly person.
  • You have high blood pressure or heart, kidney or liver diseases.
  • You develop stomach bleeding and ulcers after taking this medicine.
  • You have a history of, or you suffer from, asthma and nasal allergy.
  • You suffer from an immune disorder, where the immune system acts against the body tissues.
  • You have a hereditary disorder like G6PD deficiency or porphyria (blood disorders).
  • You are an alcoholic or had major surgery.
  • If you are trying to conceive, you must discontinue this medicine.
  • You develop skin allergies like rashes, itching, papules, blisters, etc.

Directions for use

Swallow Combiflam Tablet with a glass of water; do not crush or chew the tablet. The tablets should be taken along with your meal or after, but never on an empty stomach.

Storage and disposal

  • Store this medicine below 30°C.
  • Keep Combiflam Tablets out of reach of children and pets.

Quick tips

  • Avoid using Combiflam Tablet for an extended period without medical supervision. Exercise regularly to reduce pain and enhance your overall health.
  • Consult your doctor if your condition does not improve after 3-4 days.
  • Take Combiflam Tablet only once every 6 hours. Do not take more than 3 tablets in a single day.
  • Do not take Combiflam Tablet for more than 4 consecutive days without consulting a doctor.
  • Take it with or straight after food and never on an empty stomach. The ibuprofen in it irritates the stomach lining, and food reduces that risk.
  • Stop the tablet and see a doctor promptly if you get stomach pain that persists, vomiting of blood or dark material, or black tarry stools. These suggest bleeding from the stomach.
  • Do not take Combiflam alongside another painkiller containing ibuprofen, diclofenac, aspirin or paracetamol. Many cold, flu and combination remedies already contain paracetamol, and the doses add up to a level that can damage the liver.
  • Tell your doctor before taking it if you have kidney disease, heart failure, high blood pressure, asthma, or a history of stomach ulcer, and if you take a blood thinner, a diuretic or a blood pressure medicine.
  • Drink enough fluid while taking it and avoid it if you are dehydrated or have a vomiting illness, as anti-inflammatory painkillers can strain the kidneys in that state.
  • Avoid alcohol while taking it. Alcohol increases the risk of both stomach bleeding from the ibuprofen and liver injury from the paracetamol.

Dosage

Overdose

Taking Combiflam Tablet in high doses may result in symptoms like headache, nausea, vomiting, stomach pain, diarrhoea, low blood pressure, etc. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a dose

Do not take a double dose of Combiflam Tablet, if you have missed a dose. Take the next dose as soon as you remember. A minimum 6-hour gap is recommended between the 2 doses.

How Combiflam works

Combiflam Tablets work by inhibiting the effects of cyclooxygenase (COX) enzymes, which cause pain, inflammation, swelling, and redness.

Interactions

Drug interactions of Combiflam with other medicine salt

Methotrexate

Severe

Combiflam tablet may reduce how the body removes methotrexate, increasing its toxicity (e.g., blood disorders, liver issues).

Mifepristone

Severe

Combiflam tablet may stop Mifepristone from working correctly if used within 8–12 days.

Zidovudine

Severe

Increased risk of blood problems like anemia or bleeding, especially in HIV-positive patients with hemophilia.

Tacrolimus

Severe

May increase the risk of kidney damage when taken with the Combiflam tablet .

Aspirin

Severe

May increase the risk of gastrointestinal bleeding, ulceration, and may reduce the cardioprotective effect of low-dose aspirin.

Isoniazid

Moderate

May increase the liver toxicity of Combiflam tablet.

Lithium

Moderate

Combiflam tablet may decrease lithium elimination, raising the risk of lithium toxicity (e.g., tremors, confusion).

Warfarin

Moderate

Prolonged Combiflam tablet use may increase the effect of warfarin, raising the risk of bleeding.

Ciclosporin

Moderate

Increased risk of kidney damage when combined with NSAIDs.

Cholestyramine

Moderate

Slows down the absorption of Combiflam tablet, reducing its pain-relieving effect.

Flucloxacillin

Moderate

Combined use may lead to a dangerous chemical imbalance in the blood, especially in patients with risk factors.

Metoclopramide

Mild

May increase the rate of absorption of Combiflam tablet, leading to a faster onset of action.

Food interactions

Combiflam Tablets are advised to be taken with food, particularly if you have a sensitive stomach. Taking them with food can help mitigate some of the side effects. If you take Combiflam Tablet shortly after a meal, the onset of action may be delayed. In such cases, do not take more Combiflam Tablets than recommended or until the appropriate re-dosing interval has elapsed.

Frequently asked questions

Persistent stomach pain, vomiting blood or dark gritty material, and black tarry stools. Stop the tablet and seek medical attention the same day. The risk is higher if you are older, take it for a long period, drink alcohol, or also take a steroid, a blood thinner or another anti-inflammatory.
No, not unless your doctor says so. Combiflam already contains paracetamol. Taking them together can raise the paracetamol dose to a level that damages the liver, which may not cause symptoms until the damage is advanced.
Tell your doctor first. The ibuprofen reduces blood flow through the kidneys, which matters if kidney function is already reduced, and it can blunt the effects of blood pressure medicines and diuretics. It should be avoided or used only briefly under supervision in these situations.
It should not be. Take it with or just after food. Taking an anti-inflammatory painkiller on an empty stomach substantially increases the chance of stomach pain, irritation and bleeding.
Not without your doctor's advice, and it is generally avoided in late pregnancy because anti-inflammatory painkillers can affect the baby's circulation and reduce the fluid around the baby. Tell your doctor if you are pregnant, trying to conceive or breastfeeding.
Yes, on two fronts. Alcohol adds to the stomach irritation caused by ibuprofen, increasing bleeding risk, and it increases the strain that paracetamol places on the liver. Avoid alcohol while taking it.
No, the Combiflam Tablet is not addictive.
No, you should not take 2 Combiflam Tablets at once. Leave at least 6 hours between two Combiflam Tablets. You should not take more than 3 tablets in a 24-hour period. Avoid using this medicine for more than 4 days on self-prescription.
Combiflam Tablet starts showing its effect within 30-60 minutes after its consumption. If the pain persists after taking this medicine, do not exceed the recommended dose; consult your doctor.
Patients taking Combiflam Tablet may experience dizziness, which is a common side effect. It does not cause sleepiness or affect your sleep cycle.
Combiflam Tablet is safe and doesn't harm the kidneys when taken at the correct dose. Please consult your physician for correct dosage instructions.
Cipzox and Combiflam Tablets differ in their active ingredients and indications. Cipzox contains diclofenac, paracetamol, and chlorzoxazone, which are primarily used for the treatment of painful muscle spasms associated with musculoskeletal conditions. Combiflam Tablet contains ibuprofen and paracetamol, which are commonly used to relieve general pain and reduce fever. Consult a healthcare professional to determine the best option for your specific needs.
Combiflam and Calpol are two over-the-counter brands used to relieve pain and reduce fever. Combiflam Tablet contains both ibuprofen and paracetamol, whereas Calpol only contains paracetamol. Ibuprofen is an anti-inflammatory medication, whereas paracetamol is an analgesic. Both medications can reduce fever and relieve pain, but they contain different active ingredients. Read the labels and follow the recommended dosages for each medication. Consult a healthcare professional or a chemist if you have any concerns.
Combiflam and Diclogem are two distinct medications with distinct active ingredients and indications. Combiflam Tablet contains ibuprofen and paracetamol, which treat pain and fever. Diclogem, on the other hand, contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used to relieve pain and inflammation. Both medications serve similar functions, but their active ingredients are different. To determine the right medication and dose for your needs, consult a healthcare professional or pharmacist.
Yes, Combiflam can help relieve tooth pain, headache, sinus headache, and mild to moderate migraine pain by reducing inflammation and pain signals. However, don't self-treat repeated or severe headaches for long. Always consult a doctor or dentist if pain lasts more than a day or two.
Combiflam can help reduce fever, sore throat pain, tonsillitis discomfort, and general body aches. It helps lower your temperature and relieve pain from infections or inflammation. However, it does not cure infections; it only manages symptoms. If fever or throat pain persists beyond 2-3 days, consult your doctor for proper treatment.
Combiflam may help relieve menstrual (period) pain and cramps by reducing inflammation. However, it does not delay or stop periods. It should be used only for short-term pain relief during menstruation. If period pain is severe or irregular cycles are a concern, consult a gynecologist before using painkillers regularly.
For adults, take 1 tablet, up to 2-3 times daily after meals, as advised by a physician. Do not give Combiflam to children unless a pediatrician specifically prescribes it. Never exceed the recommended dose, as overdose can cause stomach, liver, or kidney problems. Always consult a doctor for the correct dose.
Combiflam contains ibuprofen and paracetamol, compared to Dolo 650 or Crocin, which contain only paracetamol. Brufen contains ibuprofen alone, while Saridon has a different combination. Consult your doctor to choose the right option for your specific condition. Do not self-medicate.
Combiflam contains ibuprofen and paracetamol, while Signoflam has aceclofenac, paracetamol, and serratiopeptidase. Enzoflam combines diclofenac, paracetamol, and serratiopeptidase. Voveran contains diclofenac and paracetamol. Do not switch these medications without medical advice. Always consult your doctor before switching painkillers.
Combiflam is not recommended for stomach pain, as it may exacerbate acid reflux or ulcers. It is also not meant for cough or eye pain. It may help with sinus-related headache pain, but it does not treat sinus infection itself. Always identify the cause of pain before using painkillers and consult a doctor if unsure.
Combiflam should be used with caution in diabetics, heart patients, and people with kidney or liver disease. Long-term or frequent use can increase cardiovascular and kidney risks. These patients should take Combiflam only if a doctor prescribes it and monitors them.
No, never give Combiflam to dogs or pets. Ibuprofen is toxic to animals and can cause serious harm or death. Always consult a veterinarian for pet pain management.

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Manufacturer Details

Brand: COMBIFLAM

Manufacturer Name: SANOFI

Address: Sanofi India Limited, Plot No-3501-15,6301-B-14,Gidc Estate,Ankleshwar-393002,Gujarat

Country of Origin: India

Product Fulfillment

Fulfillment Information: Combiflam Strip Of 20 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id: care@pharmeasy.in

Phone Number: 7666100300

Address: D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please visit to detailed T&C.

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