Zoryl Mp 1mg Strip Of 15 Tablets

By INTAS PHARMACEUTICALS LTD

15 Tablet(s) in Strip

MRP ₹222.00

₹190.9214% OFF

Inclusive of all taxes

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Zoryl Mp 1mg Strip Of 15 Tablets Description

Zoryl Mp 1 mg is a prescription medicine used in the treatment of Type-2 Diabetes, notably in those whose blood sugar levels cannot be managed even after proper diet and exercise. Type 2 diabetes is

a condition in which the body's ability to control and utilise sugar (glucose) as fuel is impaired. It can be due to reduced Insulin production or when body cells do not respond to insulin in the way they should. As a result, your body requires extra insulin to aid glucose absorption into your cells ((insulin resistance). Zoryl Mp 1mg tablet is a combination of three antidiabetic medicines, namely Glimepiride, Metformin, and Pioglitazone. In combination with diet and exercise, this medicine helps to improve blood sugar levels in adults with Type-2 Diabetes. It aids in the proper utilisation of insulin, resulting in decreased blood sugar levels. Side effects are Metallic taste, Hypoglycemia (low blood glucose level), Nausea, Diarrhoea, Vomiting, Taste change, Diarrhoea, Stomach pain, Headache, Edema (swelling), Weight gain, Blurred vision, Bone fracture, Respiratory tract infection. Directions for the use of Zoryl Mp 1 mg tablets should be strictly followed. This medication should be taken at the same time every day. The prescribed dose should be maintained to avoid an incidence of overdose. Sudden stopping of this medication is not advised.

Product Summary

Offer Price	₹190.92
You Save	₹31.08 (14% on MRP)
Contains	Pioglitazone(15.0 Mg) + Metformin Hydrochloride(500.0 Mg) + Glimepiride(1.0 Mg)
Uses	Treatment of Type 2 diabetes mellitus
Side effects	Taste disturbance, Nausea, Vomiting, Diarrhoea, Abdominal pain, Loss of appetite, upper respiratory tract infection, Anaemia, Visual disturbance, Weight gain, Erectile dysfunction, Bone fracture, Headache, Arthralgia
Therapy	ANTI-DIABETIC

Check more medicines with composition as Pioglitazone(15.0 Mg) + Metformin Hydrochloride(500.0 Mg) + Glimepiride(1.0 Mg)

Precautions and Warnings

Uses of Zoryl Mp 1mg Strip Of 15 Tablets

As per CDSCO, Zoryl Mp 1 mg is used in the treatment of Type 2 diabetes mellitus.

Contraindications of Zoryl Mp 1mg Strip Of 15 Tablets

Hypersensitivity to Glimepiride, Metformin or Pioglitazone, other sulfonylureas or sulfonamides or to any of the excipients
Any type of acute metabolic acidosis (such as lactic acidosis, diabetic ketoacidosis)
Insulin-dependent diabetes
Cardiac failure or history of cardiac failure
Diabetic ketoacidosis
Diabetic coma
Severe renal or hepatic function disorders
Decompensated heart failure, respiratory failure, recent myocardial infarction, shock, and other diseases that can cause tissue hypoxia (particularly acute disease or exacerbation of chronic disease)
Bladder cancer in progress or a history of bladder cancer
Alcoholism, hepatic insufficiency, acute alcohol intoxication
Conditions that can lead to renal dysfunction like dehydration, severe infection, shock
Any evidence of fluid overload
History of fracture or at high risk for fracture

Side effects of Zoryl Mp 1mg Strip Of 15 Tablets

Taste disturbance
Nausea
Vomiting
Diarrhoea
Abdominal pain
Loss of appetite
upper respiratory tract infection
Anaemia
Visual disturbance
Weight gain
Erectile dysfunction
Bone fracture
Headache
Arthralgia

Precautions and Warnings of Zoryl Mp 1mg Strip Of 15 Tablets

Pregnancy

Can I take a Zoryl Mp 1mg tablet during pregnancy?

Zoryl Mp 1mg tablets are unsafe during pregnancy. Studies have shown that it causes a definite risk to the foetus. Foetal growth restriction was reported in animal studies. If you are planning a pregnancy, you should inform your doctor.

Breast Feeding

Can I take Zoryl Mp 1mg tablets while breastfeeding?

No, individual medicines of Zoryl Mp 1mg tablets are secreted into breast milk. Because there is a risk of hypoglycaemia in nursing infants, breastfeeding is advised against during treatment with Zoryl Mp 1mg tablets.

Driving

Can I drive if I have taken the Zoryl Mp 1mg tablet?

No. You can experience visual disturbances, and you should be cautious when driving or using heavy machines.

Alcohol

Can I consume alcohol with the Zoryl Mp 1mg tablet?

No. You should not consume alcohol while on treatment with the Zoryl Mp 1mg tablet. There is an increased risk of lactic acidosis, particularly in case you are fasting or are having malnutrition or hepatic impairment.

Other General Warnings

Talk to your doctor if

You are allergic to Glimepiride, Metformin, or Pioglitazone, other sulfonylureas or sulfonamides or to any of the excipients of this medicine.
You have renal failure.
You have severe liver impairment.
You have a previous history of acute metabolic acidosis (such as lactic acidosis, diabetic ketoacidosis) with any of the component medicines of Zoryl Mp 1mg tablet.
You are having heart failure or have a history of cardiac failure.
You are a patient with bladder cancer.
You are an alcoholic.
You have an infection or are under treatment for any ongoing infection.
You have to undergo any imaging procedure involving the administration of an iodinated contrast agent.
You have to undergo surgery.
You are an elderly individual.
You develop visual impairment after starting this medicine.
You develop liver or renal failure/impairment after starting this medicine.
You have made changes in your diet or have increased physical activity. The dose needs to be adjusted based on the blood sugar levels.

Mode of Action of Zoryl Mp 1mg Strip Of 15 Tablets

How Does It Work?

Zoryl Mp 1mg tablet is a combination of three antidiabetic medicines, namely Glimepiride, Metformin, and Pioglitazone. Glimepiride belongs to the sulfonylurea class of medicine. It acts on the functi...

Directions for Use of Zoryl Mp 1mg Strip Of 15 Tablets

Take the Zoryl Mp 1mg tablet in the dose and duration as advised by your doctor.
Swallow it as a whole with a glass of water.
Do not chew, crush, or break it.
It is better to take it at a fixed time to maintain a constant level of medicine in the body and achieve the desired clinical effect.
Continue taking this medicine as long as your doctor recommends.
The prescribed dose should be maintained to avoid an incidence of overdose. Sudden stopping of this medication is not advised.

Interactions of Zoryl Mp 1mg Strip Of 15 Tablets

Interactions with other medicines

Medicines that induce the action of CYP2C9 enzyme (e.g. rifampicin) decrease concentration of individual medicines in Zoryl Mp 1mg tablets reach blood supply, thereby decreasing the efficacy of Zoryl ...
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Medicines that inhibit the action of CYP2C9 enzyme (e.g. fluconazole) increase the blood levels of individual medicines in Zoryl Mp 1mg tablets, thereby increasing the chances of side effects of Zoryl...
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Lipid reducing medicines like gemfibrozil and fenofibrate increase the blood levels of individual medicines in Zoryl Mp 1mg tablet, thereby increasing the chances of side effects of Zoryl Mp 1mg table...
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Calcium channel blocker class of antihypertensive medicine like verapamil reduce the efficacy of Zoryl Mp 1mg tablet.
Anabolic steroids like nandrolone, oxandrolone, oxymetholone - Potentiation of the blood-glucose-lowering effect.
ACE inhibitor classes of medicines like Captopril increase chances of hypoglycemia (low blood sugar).
Antibiotic chloramphenicol - Potentiation of the blood-glucose-lowering effect.
Anticoagulants like Warfarin - Potentiation of the blood-glucose-lowering effect.
Medicines used to treat Gout like Allopurinol - Potentiation of the blood-glucose-lowering effect

Interactions with food items

Food has little effect on the absorption of Zoryl Mp 1mg tablets into the blood.

Storage and disposal of Zoryl Mp 1mg Strip Of 15 Tablets

Do not store Zoryl Mp 1mg tablets above 25°C. Store in the original package. Keep it away from the reach and sight of children. Keep it away from direct sunlight, heat, and moisture. Discard the expi...

Dosage of Zoryl Mp 1mg Strip Of 15 Tablets

Overdose

Symptoms of overdose of Zoryl Mp 1mg tablet are hypoglycemia (low blood sugar levels) and lactic acidosis, which can present with nonspecific symptoms and includes severe nausea, vomiting, diarrhoea, ...

Missed a Dose

If you have missed a dose of Zoryl Mp 1mg tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with y...

Content Details

WRITTEN BY

Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

REVIEWED BY

Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)

Q: What lab tests need to be performed before or after starting Zoryl Mp 1mg tablet?

A: Liver and renal or kidney functions tests need to be performed before starting Zoryl Mp 1mg tablet. These tests might also be needed to be performed periodically thereafter. The frequency of the test monitoring would be based on clinical judgement by your doctor.

Q: Can Zoryl Mp 1mg tablet cause bone fracture?

A: There are some reports of bone fracture after starting the treatment with Pioglitazone, which is one of the component medicines of Zoryl Mp 1mg tablet. Hence it is advised to maintain proper bone health, especially in females.

Q: Can the use of Zoryl Mp 1mg tablet cause Vitamin B12 deficiency?

A: Zoryl Mp 1mg tablet contains Metformin which can cause vitamin B12 deficiency. It interferes with the absorption of vitamin B12 from the gut during long term usage.

Q: Can Zoryl Mp 1mg tablet cause hypoglycemia?

A: Yes, the use of Zoryl Mp 1mg tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include excessive sweating, hunger, fainting, fatigue, light-headedness, shakiness, nausea or vomiting, mental confusion, anxiety, blurred vision, headache, irritability, pallor, palpitations, pins and needles sensation, sleepiness, slurred speech, and tremor.

Q: Can I stop the Zoryl Mp 1mg tablet on my own?

A: It is suggested that you adhere to the dose and duration of the prescription and not discontinue taking Zoryl Mp 1mg tablet on your own, as doing so may result in recurrent symptoms or worsen the disease. If you have any problems while using Zoryl Mp 1mg tablet, please see your doctor so that you can be offered an alternative medication.

References

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Product Details

Brand

ZORYL MP

Country of Origin

India

Expires on or After

29/11/2025

Manufacturer Details

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Last Updated on: 21 Apr 2022 | 10:01 AM (IST)

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