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Ziten M 20/500mg Tab 15's
Ziten M 20/500mg Tab 15's

Ziten M 20/500mg Tab 15's

15 Tablet(s) in Strip
MRP 251.50
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Metformin(500.0 Mg) + Teneligliptin(20.0 Mg)
Therapeutic classification

Medical Description

Ziten M 500mg Tablet is a combination of Teneligliptin and Metformin. It is used to manage Type 2 diabetes mellitus. Ziten M tablet helps to maintain your blood sugar levels under control by increasing insulin production and decreasing glucose production. You may experience certain side effects like low blood sugar levels (trembling, sweating, mood disorders, blurred vision, tingling lips, paleness, irritability or confusion), nausea, stomach pain, constipation, and fatigue. Take this medicine as directed by your doctor. Long term use of this medicine can cause low levels of Vitamin B12. This medicine helps to prevent diabetes related serious complications like damage to the eyes, kidneys, nerves. It is advised that you should follow a proper diet and exercise to achieve better blood sugar controls.
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Uses of Ziten M 20/500mg Tab 15'S

It is used to treat Type 2 diabetes mellitus along with an appropriate diet and exercise.

Contraindications of Ziten M 20/500mg Tab 15'S

  • If you are allergic to this medicine or any of the ingredient of this medicine.
  • If you have liver or severe kidney problems.
  • If you are an alcoholic.
  • If you are in a state of diabetic coma due to a sudden rise or drop in blood sugar level.
  • If you have type1 diabetes mellitus.
  • If you have a severe infection or you have gone through surgery.
  • You have a known history of pancreatitis.

Side effects of Ziten M 20/500mg Tab 15'S

  • Low blood sugar level, be watchful for symptoms of low blood sugar like trembling, sweating, mood disorders, blurred vision, tingling lips, paleness, irritability or confusion
  • Nausea
  • Constipation
  • Stomach pain
  • Gases
  • Diarrhoea
  • Loss of appetite
  • Rashes, itching, allergy
  • Tiredness
  • Inflammation in pancreas
  • Decrease of vitamin B12
  • Lactic acidosis (too much acid in the body)

Precautions and Warnings of Ziten M 20/500mg Tab 15'S


Can I take Ziten M 500mg Tablet during pregnancy?
Generally, in pregnancy-related diabetes, insulin is preferred over any oral medicines. Your doctor will mostly not prescribe this medicine to you in pregnancy. Do not use this medicine in pregnancy without a doctor’s advice.

Breast Feeding

Can I take Ziten M 500mg Tablet while breastfeeding?
It is not advised to breastfeed during the treatment. It can harm the newborn baby.


Can I drive if I have consumed Ziten M 500mg Tablet?
After taking this, there are chances your blood sugar can fall. You may experience faintness, confusion and increased sweating. So, it would be best if you take extra care when driving. Keep a juice or chocolate handy while driving and in case you start experiencing any of these symptoms, immediately have it.


Can I consume alcohol with Ziten M 500mg Tablet?
  • Alcohol lowers blood sugar which can be dangerous and also increases the risk of a serious condition called lactic acidosis.
  • Alcohol can also increase the risk of developing the serious side effect of pancreatitis.

Other General Warnings

Talk to your doctor if
  • You have a known history of pancreatitis or develop sudden pain in the stomach or back, immediately stop this medicine and report to the hospital.
  • You have a liver or heart problem like irregular heartbeat and heart failure.
  • You are suffering from continuous diarrhoea, vomiting and loss of body fluids.
  • You have serious liver and kidney function problems.
  • You have an irregular diet, habit of excessive alcohol intake and intense exercise.
  • You have a history of any abdomen surgery.
  • You are using other medicines like Glimepiride because it can cause a drop in blood sugar level.
  • You experience muscle pain, stomach pain, vomiting, breathing difficulty and low body temperature. It could be a serious condition known as lactic acidosis.

Mode of Action of Ziten M 20/500mg Tab 15'S

How Does It Work?

Teneligliptin in this medicine works by increasing insulin secretion from the pancreas by inhibiting the enzyme dipeptidyl peptidase 4 (DPP4), whereas Metformin decreases the production of glucose from the liver, the amount of glucose absorbed from the intestine and increases insulin sensitivity.
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Directions for Use of Ziten M 20/500mg Tab 15'S

  • Consult your doctor for the appropriate dosage.
  • Take this medicine with or after a meal to reduce its side effects.
  • Take this tablet as a whole with a glass of water, do not break or crush the tablet.
  • Do not consume any medicine that has passed its expiry date.

Interactions of Ziten M 20/500mg Tab 15'S

Interactions with other medicines

  • If you need to take an injection of iodine-containing contrast medium into your bloodstream, for an X-ray or scan, your doctor will ask you to stop taking this medicine before or at the time of injection.
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  • You may have symptoms of low blood sugar if you are taking other medicines for diabetes like Metformin, Insulin, Canagliflozin and Liraglutide.
  • Medicines like Phenelzine used to treat mood disorders.
  • Medicines for fever and pain (salicylates like aspirin).
  • Medicines used to treat high blood pressure like Atenolol, Propranolol and Verapamil.
  • You may have high blood sugar if you are taking medicines for thyroid disorder and /or medicines that modify your immune system.
  • Never take this medicine if you are taking medicines like Quinidine, Sotalol, Procainamide and Amiodarone as it may cause heart rhythm problems and heart attack.

Other general Interactions

Absorption of vitamin B12 appears to be reduced during long-term Metformin therapy and annual screening of serum vitamin B12 levels and red blood cell parameters has been recommended.

Storage and disposal of Ziten M 20/500mg Tab 15'S

  • Store this medicine below 25°C in a cool and dry place.
  • Dispose of any medicine if it has passed its expiry date.
  • Keep this medicine away from children and pets.

Dosage of Ziten M 20/500mg Tab 15'S


  • It is always recommended to have the tablet in dose and duration as recommended by your doctor.
  • In case of an overdose, lactic acidosis (too much accumulation of acid) may occur.
  • Symptoms of lactic acidosis are vomiting, stomach and muscle cramps, difficulty in breathing.
  • Take more than recommended medicine may also cause too low blood sugar levels with symptoms like sweating, trembling, weakness, blackout, shaking and confusion.
  • You must seek immediate emergency medical care if you suspect an overdose.

Missed a Dose

If you missed a dose of this medicine, take it as soon as you remember. If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.
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Content Details


Dr. Abhishek B L

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What kind of food should I include in my diet?

  • A diet should be high in fibre, low in fat with adequate protein, carbohydrates, vitamins and minerals.
  • Maintain regular meal timings and try to have 2-3 healthy snacks between meals like soups and salads.
  • Diet should include boiled, steamed or baked food.
  • Ensure moderate use of edible oils (groundnut oil, olive oil), very little use of ghee and butter.
  • Drink at least 8-10 glass of water daily.
  • Carry fruit or low-calorie high fibre biscuits while travelling.

Q: What should I avoid doing, being a diabetic patient?

  • You could be tempted to buy oily and fried food, do not shop when you are hungry.
  • Avoid overeating.
  • Avoid maida, white bread, potato, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
  • Stop having daals with ghee or deep-fried pulses.
  • Avoid cream soups, carrot juice, deep-fried vegetables and vegetable curries with excess oil.

Q: What are the symptoms of lactic acidosis?

A: Lactic acidosis is a medical condition that arises due to too much accumulation of lactic acid in the blood. This condition is characterised by pain in muscles or weakness, dizziness, tiredness, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate, cold arms and legs. This condition is usually associated with the use of metformin. Thus patients who are elderly, who are suffering kidney disease or are chronic alcoholics are advised to use medicines containing metformin with caution.

Q: Can I stop taking this medicine as my blood sugar levels are now under control?

A: No, do not stop taking this tablet unless your doctor advises you to do so. Suddenly stopping the medicine may lead to sugar spikes which can be life threatening.
Last Updated on: 17 Apr 2021 | 01:42 PM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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