Signoflam P Tablet
Description
Signoflam P tablet is used for the management of pain, swelling, and inflammation associated with conditions like arthritis, spondylitis, and lower back pain. It can also be used to relieve a headache, toothache, ear pain, and so on. It contains aceclofenac and paracetamol as its active ingredients. It should be taken as directed by the doctor and in the correct doses for the exact duration prescribed. Before using this medicine, inform the doctor if you are pregnant, planning a pregnancy, or breastfeeding and about your detailed medical history.
Product Summary
| Offer Price | ₹110.67 |
| You Save | ₹47.43 (30% on MRP) |
| Contains | Aceclofenac(100.0 Mg)+Paracetamol / Acetaminophen(500.0 Mg) |
| Therapy | ANALGESIC/ANTIPYRETIC |

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Uses
- Signoflam P tablet is useful in relieving pain and swelling associated with bones and joints in conditions such as arthritis, spondylitis and low back pain.
- It is also useful in gynaecological pain, toothache, headache, pain and swelling in the ear, nose and throat.
Contraindications
- If you are allergic to aceclofenac, paracetamol, or any of the ingredients of Signoflam P tablet.
- If you have a history of asthma, skin rashes, swelling & nasal congestion after taking painkillers.
- If you have a history of or currently have stomach ulcers or bleeding in any part of the digestive tract.
- If you have a heart failure problem, high blood pressure, liver or kidney-related problem.
- If you are pregnant, this medicine should not be taken, especially in the third trimester of pregnancy.
Side effects
- Nausea
- Vomiting
- Indigestion
- Stomach pain
- Indigestion
- Diaarhoea
- Dizziness
- Drowsiness
- Increased liver enzymes
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have a kidney or liver problem or blood clotting disorder.
- You have a bleeding problem in the stomach, ulcers in the intestine (perforation) or Crohn's disease.
- You have asthma, as this medicine can worsen the symptoms of asthma.
- You have an autoimmune disease called systemic lupus erythematosus.
- You are an alcoholic, as concomitant use of this medicine can damage the liver.
- You experience skin rashes & lesions after taking Signoflam P tablet.
- You are an elderly patient or taking water pills or have kidney disorders; this medicine can increase the risk of kidney failure. Your doctor may ask you to do renal function tests for the same.
Directions for Use
Storage and disposal
- Store Signoflam P tablets in a cool and dry place and away from light.
- Keep it away from the sight and reach children and pets.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Some medicines can affect the way Signoflam P tablet works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Other medicines containing paracetamol should not be taken along with Signoflam P tablet, as there is an increased risk of liver damage.
- Signoflam P tablet can interfere with the blood pressure-lowering action of medicines used to treat high blood pressure.
- Medicines like water pills, digoxin (used for heart conditions), ciclosporin & tacrolimus (used to modify immune response) if taken along can lead to kidney problems and hence should be used cautiously....
- There is an increase in the risk of getting stomach ulcers or bleeding when Signoflam P tablet is taken along with steroids.
- There is a risk of bleeding if Signoflam P tablet is taken along with blood thinners such as warfarin.
- You may experience fits and seizures if you are taking this medicine with antibiotics like levofloxacin, ciprofloxacin.
- Antidiabetic medicines, if taken along with Signoflam P tablet, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat, hunger pangs.
Interactions with food items
Content Details
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Any precautions do I need to take before taking Signoflam P tablet?
- Yes, tell your doctor if you are taking any other medicine for pain, fever or arthritis.
- Take this medicine only for the duration as prescribed by your doctor. Never take more than the prescribed dose, as it can result in an overdose.
- Be cautious about stomach pain, blood in vomit, dark stools; these could be signs of bleeding in your stomach or intestine. Immediately stop taking medicine and inform your doctor.
Q: Can I take paracetamol with Signoflam P tablet?
Q: Is Signoflam P tablet a painkiller?
Q: Can I take Signoflam P tablet with antibiotics?
References
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 3 May 2021]
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 71771, Aceclofenac. Retrieved January 16, 2025
- Aceclofenac. DrugBank. [Accessed 16 Jan 2025].
- NHS. Paracetamol for adults. NHS website. [Accessed 16 Jan 2025].
- ScienceDirect. Paracetamol. ScienceDirect. [Accessed 16 Jan 2025].
- Gerriets V, Anderson J, Patel P, et al. Acetaminophen. [Updated 2024 Jan 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. [Accessed 16 Jan 2025].
- Acetaminophen. DrugBank. [Accessed 16 Jan 2025].
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