Pyzina 500mg Tablet
Pyzina 500 MG Description
Pyzina Tablet belongs to the anti-tubercular medicine group. It contains Pyrazinamide as an active ingredient. Pyzina Tablet is given in combination with at least one other anti-tubercular medicine.
Together this combination of medicine kills the bacteria called ‘Mycobacterium tuberculosis’, responsible for TB (tuberculosis) infection and hence control the infection. Tuberculosis is a potentially serious infectious lung disease that mainly affects the lungs. Still, if left untreated, it can also affect other body parts such as kidneys, brain, spine, and bone marrow. Pyzina Tablet works by inhibiting the organism's growth by lowering the pH inside the cell by converting it into an active metabolite known as pyrazinoic acid(an active form of the medicine) in the presence of the enzyme pyrazinamide. It is effective only against intracellular mycobacteria. Pyzina Tablet is given in combination with at least one other tuberculosis medicine. The most common side effects of taking a Pyzina Tablet include muscle/joint pain, nausea, vomiting and loss of appetite. These symptoms usually resolve with time and do not require urgent medical attention. However, you are advised to talk to your doctor if you experience these side effects persistently or any other serious side effects. Before taking this medicine, you should tell your doctor about your past medical history.
Product Summary
Offer Price | ₹51.30 |
You Save | |
Contains | Pyrazinamide(500.0 Mg) |
Uses | Tuberculosis (TB) |
Side effects | Muscle/joint pain, nausea, vomiting, loss of appetite, hepatitis, liver dysfunction, unusual tiredness and weakness, yellow-coloured eyes or skin, dark urine, skin rash, photosensitivity |
Therapy | ANTI-TUBERCULAR |
Uses of Pyzina 500 MG
- Treatment of Tuberculosis (TB)
Contraindications of Pyzina 500 MG
- Allergy
- Severe Liver disease
- Acute Gout
- Porphyria
- Pregnancy
- Breastfeeding
Side effects of Pyzina 500 MG
- Muscle/joint pain
- Nausea
- Vomiting
- Loss of appetite
- Hepatitis
- Liver dysfunction
- Unusual tiredness and weakness
- Yellow-coloured eyes or skin
- Dark urine
- Skin rash
- Photosensitivity
Precautions and Warnings of Pyzina 500 MG
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have liver toxicity
- You have jaundice
- You have photosensitivity after taking this medicine
- You have gout (a form of arthritis)
Mode of Action of Pyzina 500 MG
How Does It Work?
Directions for Use of Pyzina 500 MG
- Take Pyzina Tablet with a glass of water, preferably at a fixed time.
- Do not crush, chew, or break the tablets.
- Take this tablet with or without food or as prescribed.
- The dose and duration should be followed as prescribed by your doctor.
- Do not take doses in larger amounts than advised.
- Consult your doctor if you experience any serious side effects.
- Do not abruptly stop taking medicine without consulting your doctor as it may cause medicine-resistant tuberculosis, which is difficult to treat.
Interactions of Pyzina 500 MG
Interactions with other medicines
- Probenecid, Sulfinpyrazone, Oral Contraceptive Pills, Methotrexate, Cholera Vaccine, Lomitapide, Efavirenz, Cyclosporine, Cannabidiol
Interactions with food items
- There is not enough research available regarding the interaction of Pyzina Tablet with food and beverage.
Storage and disposal of Pyzina 500 MG
Dosage of Pyzina 500 MG
Overdose
Missed a Dose
Content Details
Dr. Zishan Ahmad
MBBS, MD
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: How long does it take for Pyzina Tablet to show its effect?
Q: Is this a habit-forming medicine?
Q: Can I discontinue taking Pyzina Tablet on my own after the desired effect?
References
- Katzung BG. eds. Basic & Clinical Pharmacology, 14e. McGraw Hill; 2017. Accessed December 20, 2021.
- Tripathi, K. D. (2018). Essentials of medical pharmacology (8th ed.). Jaypee Brothers Medical.
- Rifampin, Isoniazid, And Pyrazinamide (Oral Route) Side Effects - Mayo Clinic [Internet]. Mayoclinic.org. 2022 [cited 20 december 2021]. Available from
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