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Monocef Sb 1gm Inj

1g Powder For Injection in Dry Vial

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Ceftriaxone(1.0 G) + Sulbactam(500.0 Mg)
Therapeutic classification

Medical Description

Monocef-SB 1gm injection contains a combination of ceftriaxone and sulbactam, a higher antibiotic medicine. Monocef-SB 1gm Injection is used to treat various types of bacterial infection. This injecti...
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    Side effects
    Precautions and Warnings
    Mode of Action
    Directions for Use
    Storage and disposal
    Other Products
    Quick Summary

Uses of Monocef Sb 1gm Inj

Monocef-SB 1gm injection is used for severe and serious infections like urinary tract, respiratory tract (lungs, airways), blood, brain and infections caused by bacteria that do not respond to other a...
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Contraindications of Monocef Sb 1gm Inj

  • If you are allergic to ceftriaxone, sulbactam or any of the ingredient of Monocef-SB 1gm injection.
  • If you are allergic to cephalosporins, penicillins, monobactams and carbapenems.
  • If the patient is a premature baby.
  • If a newborn has jaundice or is on calcium injection.
  • If a newborn is suffering from increased bilirubin (liver enzyme) in the blood.

Side effects of Monocef Sb 1gm Inj

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Fever
  • Loose stools
  • Flushing
  • Rash
  • Itching and pain at the injection site

Precautions and Warnings of Monocef Sb 1gm Inj



Can I take Monocef-SB 1gm injection during pregnancy?
There is limited information available about the safety of Monocef-SB 1gm injection during pregnancy. Consult your doctor if you are pregnant, your doctor will tell you about the use of this medicine after assessing the need.

Breast Feeding

Can I take Monocef-SB 1gm injection while breastfeeding?
  • The components of Monocef-SB 1gm injection pass into breast milk, inform your doctor if you are breastfeeding, your doctor will tell you on the use of this medicine after assessing the need and benefi...
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  • Monitor your baby for antibiotic-related side effects like diarrhoea or fungal infection of the mouth.


Can I drive if I have consumed Monocef-SB 1gm injection?
You may feel dizzy after taking Monocef-SB 1gm injection. Therefore, be cautious or avoid driving after taking this injection.


Can I consume alcohol with Monocef-SB 1gm injection?
Alcohol may worsen the side effect like dizziness when consumed with Monocef-SB 1gm injection. It is advisable to avoid alcohol after getting injected.

Other General Warnings

Talk to your doctor if
  • You have a history of allergy after taking this antibiotic.
  • You have developed diarrhoea after taking this medicine, immediately stop this medicine and inform your doctor.
  • You have serious liver and kidney disease.
  • You are suffering from gall bladder disease.
  • You are suffering from anaemia.
  • You are suffering from the disease bowel inflammation (Colitis).

Mode of Action of Monocef Sb 1gm Inj

How Does It Work?

  • Monocef-SB 1gm injection acts by killing the bacteria responsible for infections.
  • However, bacteria make an enzyme (beta-lactamases) that can destroy Ceftriaxone.
  • Sulbactam inactivates this enzyme and hence helps Ceftriaxone to function optimally.

Directions for Use of Monocef Sb 1gm Inj

Monocef-SB 1gm injection will be given in a hospital by your doctor or nurse as an injection. Do not self inject this medicine.

Interactions of Monocef Sb 1gm Inj

Interactions with other medicines

  • Monocef-SB 1gm injection should never be given along with Ringer's or Hartmann's solution.
  • If you are taking warfarin, then there is an increased risk of bleeding.
  • This injection should never be given through the IV line through which calcium-containing solutions are given.

Storage and disposal of Monocef Sb 1gm Inj

  • Store Monocef-SB 1gm injection below 25°C.
  • Protect it from light.
  • Keep it out of the reach of children.
  • Any unused portion should not be stored and should be discarded properly.

Dosage of Monocef Sb 1gm Inj


Your doctor or nurse will give this injection. Therefore it is less likely you shall receive more of this medicine. However, if you experience any side effects after taking this injection, inform your...
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Missed a Dose

You will be monitored by your doctor or nurse on when the injection should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a ...
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Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Any precautions do I need to take before taking Monocef-SB 1gm injection?

A: You need to inform your doctor if you have any allergy to any other antibiotic or specific allergen.

Q: For how long do I need to take Monocef-SB 1gm injection?

A: You are supposed to complete the prescribed duration of antibiotics by your doctor. Otherwise, there is a possibility of reoccurrence of the infection.

Q: How to give Monocef-SB 1gm injection?

A: Monocef-SB 1gm injection is usually given intravenously or intramuscularly under medical supervision. This medicine will only be by nurse or doctor. The route of administration is usually being decided by your doctor. Do not self-inject.

Q: Can the Monocef-SB 1gm Injection use to treat urinary tract infection (UTI)?

A: Yes, the Monocef-SB 1gm Injection can be used to treat urinary tract infection (UTI) caused by infection-causing bacteria. Your doctor may prescribe you this medicine based on the condition of your infection and its severity.

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Quick Summary

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ContainsCeftriaxone(1.0 G),Sulbactam(500.0 Mg)
UsesBacterial infection
Side effectsPain, inflammation and swelling at injection site, diarrhoea
Last Updated on: 21 Aug 2021 | 10:23 AM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case case of any queries or doubts. Please click here for detailed T&C.