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Gentamicin

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Molecule Summary

Uses
Urinary tract infections, chest infections, bacteria in blood
Therapy
Antibiotic
Side Effects
Kidney problems, dizziness, ringing in ears, vertigo, diarrhoea, vision problems
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Molecule Description

Gentamicin is an antibiotic classified as an aminoglycoside. It is used to treat bacterial infections in the urine, chest, and blood. Gentamicin works by killing bacteria by targeting their proteins.

Uses

  • Urinary tract infections
  • Chest infections
  • Bacteria in blood

Contraindications

When should one not use Gentamicin

  • Known allergy to any ingredients of this medicine
  • Myasthenia gravis

Side effects

Common side effects of this drug are:

  • Kidney problems
  • Dizziness
  • Ringing in ears
  • Vertigo
  • Diarrhoea
  • Vision problems

Precautions and Warnings

Pregnancy

Pregnancy

Your doctor will recommend Gentamicin during pregnancy only if you have a life-threatening condition.

Breast Feeding

Breast Feeding

No, you should not take Gentamicin while breastfeeding unless your doctor advises it. This is due to a small amount of the medication passing into breast milk.

Driving

Driving

Gentamicin can cause dizziness or vertigo as the side effect; hence, avoid driving after taking this medicine.

Alcohol

Alcohol

Gentamicin and alcohol may cause dizziness and drowsiness. Hence it should be avoided.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have kidney problems
  • You have Parkinson's disease or any other neuromuscular condition
  • You are currently using other antibiotics
  • You are allergic to other antibiotics
  • You have Myasthenia gravis

Mode of Action

How Does It Work?

Gentamicin is an antibiotic. It works by stopping the synthesis of proteins in the bacteria which ultimately kills them.

Interactions

Interactions with other medicines

  • Gentamicin increases the effects of ether and other muscle relaxants.
  • Concomitant administration of methoxyflurane can damage the kidneys.
  • Concomitant administration of Indomethacin increases blood levels of gentamicin in newborn babies.
  • Oral anticoagulants and gentamicin can cause clotting problems.
  • Concomitant administration of neostigmine or pyridostigmine can cause the opposite effect to Gentamicin.
  • Concomitant administration of Botulinum toxin increases toxicity.
  • Concomitant administration of Cephalothin, cephaloridine, colistin, vancomycin, viomycin, streptomycin, amphotericin B, cisplatin, or loop diuretics can cause hearing problems or toxicity in kidneys.

Dosage

Overdose

An overdose is unlikely with Gentamicin since it is given by a doctor or nurse. In case you feel unusual symptoms after taking this medicine, inform your doctor or visit the nearest hospital immediately.

Missed a Dose

In case of a missed dose, inform your doctor.

Frequently Asked Questions (FAQs)

No, Gentamicin does not cause weight gain.

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