Eliwel 25mg Strip Of 10 Tablets
10 Tablet(s) in StripWe do not sell this product
Made by
SUN PHARMA
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Amitriptyline(25.0 Mg) |
| Uses | Treatment of depression, neuropathic pain, and migraine |
| Therapy | Anti-depressant |
| Side effects | Constipation, urinary retention, Weight gain, Confusion, Orthostatic hypotension (sudden lowering of blood pressure on standing), Tiredness, Blurred vision, Dryness in the mouth |
Assurance
available
Regulated
Medical Description
Eliwel is a prescription medication. It contains the drug Amitriptyline, which belongs to a group of medications called tricyclic antidepressants. Apart from its use in the treatment of major depressive disorders, it is also commonly used to manage neuropathic pain and migraine in varying doses.
Depression is a mood disorder resulting in hopelessness, helplessness, and worthlessness. It is thought to arise due to an imbalance in the brain, among several other causes. This imbalance could be due to a lower level of chemical substances in the brain called neurotransmitters. Amitriptyline acts on multiple brain pathways to increase levels of certain neurotransmitters, effectively decreasing the symptoms of depression.
The medication should be taken as recommended by your treating physician. It is generally advisable to take the tablet at the same time every day as this ensures the best action of the medication, decreasing the chances of relapse of symptoms significantly. It is also recommended to complete the entire course of the medication as prescribed by the treating physician. Abruptly stopping this drug can cause worsening symptoms.
Uses
- Treatment of Major Depressive Disorder
- Treatment of Neuropathic pain
- Treatment of Migraines
Contraindications
Hypersensitivity
Acute recovery phase following heart attack/myocardial infarction (MI)
Concurrent use with cisapride, which is used to treat gastric reflux
Contraindicated within 14 days of monoamine oxidase inhibitors (MAOIs), like Selegiline and Rasagiline.
Should not be used with medications that can cause QT prolongation
Should not be used with medications that also increase serotonin levels
Should be used with caution in patients with angle-closure glaucoma, urinary retention, seizures
Should not be used immediately before surgery as mixing with anaesthetic agents may cause heart abnormalities like arrhythmias
Contraindicated in children < 12 years of age
Should be used cautiously in adolescents and young adults <24 years of age as it may increase suicidal ideation
Side effects
- Weight Gain
- Constipation
- Xerostomia
- Dizziness
- Headache
- Somnolence/ Sleepiness
- Urinary retention
- Dry mouth
- Orthostatic hypotension (sudden lowering of blood pressure on standing up)
- Dizziness
- Blurred vision
- Increased heart rate (tachycardia)
- Confusion
- Delirium
- Acute angle glaucoma
- Increased appetite
- Decrease of seizure threshold in patients with epilepsy/ seizure disorder
- Increased risk of bone fractures
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- In case you have ever had any thoughts about suicide.
- Disclose any history of heart disease.
- As Eliwel has multiple drug interactions, always inform your doctor of any medications or herbal products you are taking.
Directions for Use
- This medication should be taken as prescribed by the treating physician.
- It is recommended to take this medication on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of this medication.
- Swallow this medication whole. Do not crush, chew or break this tablet.
- It is recommended to finish the entire course of this medication as prescribed by your treating doctor. Abrupt stoppage of the drug can cause withdrawal side effects. Consult your doctor before stopping this medication.
- This medication may require 2-4 weeks for onset of action. Do not increase the dose without explicit advice from your treating physician.
- Driving/ use of heavy machinery is not advised while using this medication.
Storage and disposal
Store in a cool and dry place away from direct light and moisture. Do not use the medicine after expiration. Keep the tablets away from children and pets. Do not flush the medication down the toilet. Dispose of it with biomedical waste only.
Dosage
Overdose
- Amitriptyline toxicity is seen in doses over 5 mg/kg. Amitriptyline toxicity can be severe and even fatal. In the event of an overdose, the patient may present with sedation, seizure, coma, abnormal heart rhythm, dilated pupils, dry mouth. In case of a suspected overdose, immediately rush the patient to the nearest tertiary care hospital for emergency management as it is life-threatening. Do not consume the medication in a dose higher than prescribed by the doctor.
Missed a Dose
If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it is recommended to skip the missed dose and go back to the regular schedule. Do not double the dose of the tablet.
Mode of Action
How Does It Work?
Amitriptyline is a tricyclic anti-depressant (TCA). It acts on certain chemical messengers in the brain that convey signals along nerve pathways, otherwise known as neurotransmitters. The neurotransmitters involved here are serotonin and norepinephrine. After their action, these chemicals are reabsorbed by the nerves, a process known as reuptake. Amitriptyline blocks this reuptake process and results in a higher level of the drug. Chronic use can produce long-term changes in this pathway.
In addition, it also has sedative properties. When used for long, there is an increase in the levels of BDNF (brain-derived neurotrophic factor). BDNF plays an important role in causing depression. Higher levels of BDNF can reduce symptoms of depression. The action of this drug on serotonin and nor-epinephrine is also indicated in the management of neuropathic pain and migraine.
It is important to note that Eliwel as an anti-depressant requires about 2-4 weeks of continued use for the optimal onset of action to begin.
Interactions
Interactions with other medicines
- This medication causes prolongation of QTc interval and may result in cardiac arrhythmias. Do not take it with astemizole, cisapride, disopyramide, ibutilide, indapamide, pentamidine, pimozide, procainamide, quinidine, sotalol, terfenadine.
- This medication should not be used with MAOIs (Monoamine oxidase inhibitors) or within 14 days of the use of MAOIs and vice versa. Examples of MAOIs include Selegiline, Rasagiline.
- This medication should not be used with other drugs known to increase serotonin levels, like isocarboxazid, phenelzine, procarbazine, safinamide, selegiline, tranylcypromine, sertraline, as it may cause Serotonin syndrome, a potentially fatal condition.
- This medication should not be used with alcohol or other CNS depressants.
- This medication should not be mixed with opioid medications or benzodiazepines.
- Amitriptyline gets metabolised through CYP3A4. Several drugs alter the activity of CYP3A4, and thus dose should be cautiously regulated, as well as the entire patient medication regimen checked for CYP3A4 inducers and inhibitors.
Interactions with food items
This medication can be taken with or without food.
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Manufacturer Details
Brand:ELIWEL
Manufacturer Name:SUN PHARMA
Address:<p>1. 90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001</p>
Country of Origin:India
Vendor Details
Fulfillment Information: Eliwel 25 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
