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Deriva Cms Gel
Deriva Cms Gel
Deriva Cms Gel
Deriva Cms Gel

Deriva Cms Gel

15g Gel in Tube
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Therapeutic classification:


Medical Description

Deriva-CMS gel contains two medicines, Clindamycin and Adapalene. Deriva-CMS gel is used for the treatment and management of acne. Clindamycin is an antibiotic and Adapalene is a medicine derived from vitamin A. Deriva-CMS gel inhibits the growth of bacteria causing pimples, reduces swelling and inhibits the formation of blemish due to accumulation of oil and dirt. Avoid excessive use of makeup, other products on your skin when using this gel. Avoid using it if you are pregnant or breastfeeding. Do not pop acne as that leads to bacteria, pus spreading on the skin that can lead to the spread of acne and acne scar.
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Uses of Deriva Cms Gel

Treatment of acne vulgaris.

Contraindications of Deriva Cms Gel

  • If you are allergic to Clindamycin, Adapalene or any other components of this gel
  • If you have a history of inflammatory bowel disease
  • If you have experienced diarrhoea upon antibiotic use

Side effects of Deriva Cms Gel

  • Skin peeling
  • Skin irritation
  • Itching
  • Dry skin
  • Oily skin
  • Burning
  • Hives
  • Redness
  • Swelling

Precautions and Warnings of Deriva Cms Gel


Can I apply Deriva-CMS gel during pregnancy?
Deriva-CMS gel is applied to the skin and the quantities which might get absorbed from the skin is too little. The chances of any effect in pregnancy are rare. Still, this medicine should be used only under medical supervision as components of this medicine are known to be unsafe during pregnancy, especially in the first trimester. In case you are prescribed with this medicine, avoid using in larger skin areas for a prolonged duration.

Breast Feeding

Can I apply Deriva-CMS gel while breastfeeding?
It should not be applied to the breast or areas near the breast of breastfeeding mothers as there can be chances of ingestion of this by a breastfed infant. Avoid using it on large areas of skin or for a prolonged period.


Can I drive if I have applied Deriva-CMS gel?
It does not influence your driving ability.


Can I consume alcohol if I have applied Deriva-CMS gel?
There is no direct interaction between alcohol and Deriva-CMS gel. However, alcohol is known to worsen the infection and inflammation; it's better to avoid consuming alcohol when you are prescribed with this gel.

Other General Warnings

Talk to your doctor if
  • You experience skin reactions like dryness, skin peeling, burning sensation
  • Your skin may get more sensitive to sunlight after using this gel, protect the area from direct sunlight
  • You have a history of inflammation of the colon or antibiotic-associated diarrhoea
  • Deriva-CMS gel should not come in contact with the eyes, mouth, nostrils or internal surfaces of the skin
  • In case your eyes come in contact with this medicine, wash with warm water immediately
  • You should not use this gel if you are prone to allergies (atopic)

Mode of Action of Deriva Cms Gel

How Does It Work?

  • Deriva-CMS Gel works by combined action of its two components Clindamycin and Adapalene.
  • Clindamycin inhibits the protein synthesis in the bacteria responsible for causing infection and thus inhibits the growth of infection-causing bacteria.
  • Adapalene acts by inhibiting the rooting of pimples inside the skin and decreases swelling and inflammation. It also removes dead skin cells and enhances deeper penetration of Clindamycin.

Directions for Use of Deriva Cms Gel

  • Use this Deriva-CMS gel as directed by your doctor for external use only
  • Apply it on the skin surface free from cuts & wounds
  • Wash your hands before & after using this medicine
  • In case your eyes come in contact with this gel, rinse your eyes with clean water immediately
  • Avoid touching the tip of the container directly to the infected area of the skin

Interactions of Deriva Cms Gel

Interactions with other medicines

  • There is limited information available on the interaction of Deriva-CMS gel with other medicines. However, as this gel contains Clindamycin & Adapalene, any interaction seen with these two components when taken alone may occur with this combination.
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  • Deriva-CMS gel is meant for local application on skin and thus is less likely to interact with other medicines taken orally
  • However, it may interact with other topically applied medicine. Discuss with your doctor if you are already on another topical medicine.
  • Be cautious if you are taking oral anticoagulants like Warfarin, Acenocoumarol and Fluindione as components of this medicine may interact with the gel. Regular monitoring of blood coagulation parameters is recommended.
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Storage and disposal of Deriva Cms Gel

  • Store this medicine below 30°C
  • Try to keep it out of the reach of children

Dosage of Deriva Cms Gel


As Deriva-CMS gel is meant for external application, cases of overdose are unlikely. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital. If you have overapplied it, wipe out excess of medicine with tissue or cotton.
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Missed a Dose

If you missed any application of this gel, apply it as soon as you remember. If its time for your next application, skip the missed application and continue with your regular schedule. Do not overapply this medicine to compensate for the missed one.
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What precautions do I need to take before applying Deriva-CMS gel?

  • Do not use it for a longer time than your doctor suggested
  • Do not apply the gel to windburned or sunburned skin or on open wounds
  • Do not use this medicine in or around the eyes, lips or inside the nose
  • Rub in gently and well on the infected part of the skin
  • Wash your hands before and after application of Deriva-CMS gel

Q: For how long do I need to apply this gel?

A: Keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

Q: Can I use Deriva-CMS gel for children?

A: Safety and effectiveness of Deriva-CMS gel in pediatric patients under the age of 12 have not been established.

Q: Can I use Deriva-CMS gel in viral infections?

A: Clindamycin is an antibacterial medicine and is not effective against viral infections.

Q: Does Deriva-CMS gel remove scars?

A: Yes, adapalene present in the gel can help in reducing the scars after acne.

Q: How to apply Deriva-CMS gel on the face?

  • Wash your face with a soap or face wash and pat it dry
  • Wash your hands before applying the Acnestar gel
  • Apply a thin layer, rub it thoroughly and let it get absorbed
  • Avoid touching and pressing the acne, pimple too firmly while using it
  • Repeat it as prescribed by your doctor
Last Updated on: 15 Aug 2020 | 09:18 AM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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  • Uses
  • Contraindications
  • Side effects
  • Precautions and Warnings
  • Mode of Action
  • Directions for Use
  • Interactions
  • Storage and disposal
  • Dosage
  • FAQs
  • References
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