Depranil Plus Tablets
Depranil Plus Tablets Description
Depranil Plus Tablet is a prescription medication. It is used in the treatment of all kinds of depression, such as depression due to illness, severe potentially suicidal depression, and neurotic and
reactive depression. This mental disorder causes persistent feelings of sadness, irritability, and loss of interest in life. It may be associated with other types of mood disorder or phobic states like the fear of flying, heights, agoraphobia (fear of open places and crowds), etc. The active ingredients in Depranil Plus tablets are Imipramine and Diazepam. The mode of action of Depranil Plus tablets is by increasing the levels of a specific chemical messenger in the brain, responsible for balancing mood swings and providing a calming effect. Directions for use of Depranil Plus Tablet should be strictly followed. Do not suddenly stop this medicine as this can cause withdrawal symptoms like sweating, shaking, irritation, etc. Depranil Plus tablet use should be monitored for suicidal tendencies.
Product Summary
Offer Price | ₹14.61 |
You Save | ₹1.99 (12% on MRP) |
Contains | Imipramine(25.0 Mg) + Diazepam(5.0 Mg) |
Uses | All types of depression |
Side effects | Sleepiness, Dry mouth, Nausea, Vomiting, Diarrhoea, Constipation, Nervousness, Decreased sexual drive or ability, Decreased concentration and memory |
Therapy | ANTI-DEPRESSANT |
Uses of Depranil Plus Tablets
- As per CDSCO, Depranil Plus tablets are used to manage all kinds of depression symptoms.
Contraindications of Depranil Plus Tablets
Side effects of Depranil Plus Tablets
- Side effects of Depranil Plus tablets include:
- Sleepiness
- Dry mouth
- Nausea
- Vomiting
- Diarrhoea
- Decreased sexual drive or ability
- Decreased concentration and memory
Precautions and Warnings of Depranil Plus Tablets
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have suicidal thoughts after taking Depranil Plus tablets.
- You use tobacco products. Cigarette smoking may reduce the effectiveness of this medicine.
- You are an older adult over 65. The dose of Depranil Plus tablets needs to be carefully monitored to prevent excessive side effects.
- You have a history of diabetes, irregular heartbeat, blood pressure issues, thyroid problems, etc.
- You use Ayurvedic or herbal medicines (St John's wort). Interaction with these can cause Serotonin Syndrome with life-threatening side effects like agitation, delirium, and coma.
Mode of Action of Depranil Plus Tablets
How Does It Work?
Directions for Use of Depranil Plus Tablets
- Take the tablet in the exact dose and at the same time every day as prescribed by the doctor.
- Do not exceed the dosage of Depranil Plus tablets, even if you cannot notice its effects.
- Take this tablet as a whole with a glass of water, without breaking, chewing or crushing it.
- Do not use Depranil Plus tablets with other medications without informing your doctor.
- Do not abruptly stop this medication; this can result in withdrawal effects.
Interactions of Depranil Plus Tablets
Interactions with other medicines
- Do not use Depranil Plus tablets along with monoamine oxidase inhibitors (MAOIs) like linezolid, methylene blue, phenelzine, selegiline, etc. This can result in side effects like tremors, severe seizures, etc. It can sometimes even cause death. Maintain a gap of at least 14 days between these medications....
- Do not take medicine with a similar composition as Depranil Plus tablets. Compounds like sertraline, fluoxetine, paroxetine, etc. can exaggerate the side effects of Depranil Plus tablets.
- Do not use this tablet with other medicines that cause sedation and drowsiness, like tranquillisers, narcotic pain relievers, muscle relaxants, etc.
- Some other medicines that can react with Depranil Plus tablets are:
- Blood thinners (warfarin)
- Heart medication (digoxin)
- anticholinergic medicines (including anti-Parkinsonism agents like levodopa)
- Anti-seizure medications (phenytoin, phenobarbital)
- High blood pressure medicines
Interactions with food items
- Avoid grapefruit and cranberry (and their juice). These fruits can increase the levels of this medicine in your blood and cause unwanted adverse effects.
Storage and disposal of Depranil Plus Tablets
Dosage of Depranil Plus Tablets
Overdose
Missed a Dose
Content Details
Dr. Vijay Y
MBBS, MD in Clinical Pharmacology
Frequently Asked Questions (FAQs)
Q: Can I take a Depranil Plus tablet if I have diabetes?
Q: Will I gain weight while using Depranil Plus tablets?
Q: Is the Depranil Plus tablet a habit-forming medicine?
References
- Imipramine: Medlineplus Drug Information [Internet]. MedlinePlus. U.S. National Library of Medicine [cited 5 Mar 2022] -
- Diazepam: Medlineplus Drug Information [Internet]. MedlinePlus. U.S. National Library of Medicine [cited 5 Mar 2022] -
- Imipramine [Internet]. Drugs and Lactation Database (LactMed) [Internet]. U.S. National Library of Medicine.2021 [cited 5 Mar 2022] -
- Fpolslper OH. Withdrawal Reactions to Diazepam in Combined Imipramine/Diazepam Treatment of Primary Nonagitated Depressed Outpatients [Internet]. Acta Psychiatrica Scandinavica. U.S. National Library of Medicine [cited 5 Mar 2022] -
- Fernstrom MH, Krowinski RL, and Kupfer DJ. Chronic Imipramine Treatment and Weight Gain [Internet]. Psychiatry Research. U.S. National Library of Medicine [cited 5 Mar 2022] -
- CDSCO [Internet]. cdscoonline.gov.in. 2022 [cited 5 Mar 2022] -
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