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Depranil Plus Tab

By LA PHARMACEUTICALS
10 Tablet(s) in Strip
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Imipramine(25.0 Mg) + Diazepam(5.0 Mg)
Therapeutic classification
ANTI-DEPRESSANT

Medical Description

Depranil Plus Tablet is a prescription medication. It is used in the treatment of all kinds of depression, such as depression due to illness, severe potentially suicidal depression, and neurotic and r...
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Uses of Depranil Plus Tab

  • As per CDSCO, Depranil Plus tablets are used to manage all kinds of depression symptoms.

Contraindications of Depranil Plus Tab

Do not take Depranil Plus tablets or use caution: If you have an allergic reaction to Imipramine or Diazepam If you are using other antidepressant medications If you notice sudden mood changes, ...
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Side effects of Depranil Plus Tab

  • Side effects of Depranil Plus tablets include:
  • Sleepiness
  • Dry mouth
  • Nausea
  • Vomiting
  • Diarrhoea
  • Decreased sexual drive or ability
  • Decreased concentration and memory

Precautions and Warnings of Depranil Plus Tab

Pregnancy

Q:
Can I take Depranil Plus tablets during pregnancy?
A:
No. Depranil Plus tablets may not be safe during pregnancy. There is not enough data on the side effects of this medicine on pregnant women and foetuses. Consult your doctor before using Depranil Plus tablets if you are pregnant or planning to conceive.

Breast Feeding

Q:
Can I take Depranil Plus tablets while breastfeeding?
A:
No. Depranil Plus tablets are not advised for nursing mothers. Some data suggests this medicine may seep into breast milk and cause withdrawal symptoms in breastfed infants.

Driving

Q:
Can I drive if I have taken a Depranil Plus tablet?
A:
No. Depranil Plus tablets can cause adverse effects like drowsiness, slow reflexes, dizziness, difficulty concentrating, etc., affecting your ability to drive or operate heavy machinery.

Alcohol

Q:
Can I consume alcohol with Depranil Plus tablets?
A:
Depranil Plus tablets with alcohol can cause increased side effects like extreme drowsiness, lethargy, vomiting, agitation, blurry vision, double vision, muscle stiffness, sweating, etc.

Other General Warnings

Talk to your doctor if
  • You have suicidal thoughts after taking Depranil Plus tablets.
  • You use tobacco products. Cigarette smoking may reduce the effectiveness of this medicine.
  • You are an older adult over 65. The dose of Depranil Plus tablets needs to be carefully monitored to prevent excessive side effects.
  • You have a history of diabetes, irregular heartbeat, blood pressure issues, thyroid problems, etc.
  • You use Ayurvedic or herbal medicines (St John's wort). Interaction with these can cause Serotonin Syndrome with life-threatening side effects like agitation, delirium, and coma.

Mode of Action of Depranil Plus Tab

How Does It Work?

The Depranil Plus tablet contains Imipramine and Diazepam as its active substance. Imipramine is a tricyclic antidepressant medication. It is believed that it works by stopping the reuptake of che...
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Directions for Use of Depranil Plus Tab

  • Take the tablet in the exact dose and at the same time every day as prescribed by the doctor.
  • Do not exceed the dosage of Depranil Plus tablets, even if you cannot notice its effects.
  • Take this tablet as a whole with a glass of water, without breaking, chewing or crushing it.
  • Do not use Depranil Plus tablets with other medications without informing your doctor.
  • Do not abruptly stop this medication; this can result in withdrawal effects.

Interactions of Depranil Plus Tab

Interactions with other medicines

  • Do not use Depranil Plus tablets along with monoamine oxidase inhibitors (MAOIs) like linezolid, methylene blue, phenelzine, selegiline, etc. This can result in side effects like tremors, severe seizu...
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  • Do not take medicine with a similar composition as Depranil Plus tablets. Compounds like sertraline, fluoxetine, paroxetine, etc. can exaggerate the side effects of Depranil Plus tablets.
  • Do not use this tablet with other medicines that cause sedation and drowsiness, like tranquillisers, narcotic pain relievers, muscle relaxants, etc.
  • Some other medicines that can react with Depranil Plus tablets are:
  • Blood thinners (warfarin)
  • Heart medication (digoxin)
  • anticholinergic medicines (including anti-Parkinsonism agents like levodopa)
  • Anti-seizure medications (phenytoin, phenobarbital)
  • High blood pressure medicines

Interactions with food items

  • Avoid grapefruit and cranberry (and their juice). These fruits can increase the levels of this medicine in your blood and cause unwanted adverse effects.

Storage and disposal of Depranil Plus Tab

Store Depranil Plus tablets in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the ...
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Dosage of Depranil Plus Tab

Overdose

Depranil Plus tablet overdose can lead to symptoms like extreme drowsiness, nausea, irregular or fast heartbeat, dizziness, fainting, seizures, decreased urination, unusual movements, slow breathing, ...
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Missed a Dose

If you have missed a dose of Depranil Plus tablet, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with ...
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Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Vijay Y

MBBS, MD in Clinical Pharmacology

Frequently Asked Questions (FAQs)

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Q: Can I take a Depranil Plus tablet if I have diabetes?

A: Persons with diabetes should be monitored for worsening blood sugar levels when under treatment with Depranil Plus tablets, especially if the dosage has been altered. Studies have shown varying results. Some show raised blood sugar levels, while some show the opposite. Regular monitoring of your blood sugar levels is essential.

Q: Will I gain weight while using Depranil Plus tablets?

A: A study indicates weight gain from long-term use of Depranil Plus tablets. However, the results are not conclusive. Try to stay active and eat healthy food to maintain a stable weight.

Q: Is the Depranil Plus tablet a habit-forming medicine?

A: The Diazepam part of Depranil Plus tablets is a highly addictive and commonly abused medication. It also has habit-forming potential. The dose of this medication should be carefully monitored. It can also cause adverse withdrawal effects when stopped suddenly. The dose should be slowly tapered. Consult your doctor.
Product Details
Brand
DEPRANIL PLUS
Country of Origin
India
Expires on or After
15/08/2022

Quick Summary

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ContainsImipramine(25.0 Mg),Diazepam(5.0 Mg)
UsesAll types of depression
Side effectsSleepiness, Dry mouth, Nausea, Vomiting, Diarrhoea, Constipation, Nervousness, Decreased sexual drive or ability, Decreased concentration and memory
Last Updated on: 14 Mar 2022 | 10:03 AM (IST)
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.