Crocin Advance Tablet
By GLAXOSMITHKLINE
15 Tablet(s) in Strip
₹12.38
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₹16.50
25% OFF
₹0.83/tablet
(Inclusive of all taxes)
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Description
Crocin Advance 500 tablet is used to relieve pain and reduce fever. Its active ingredient is paracetamol. It is an analgesic (pain reliever) and an antipyretic (fever reducer), used for mild to moderate pain, including headaches, migraines, toothaches, menstrual pain, lower back pain, and muscle aches. The medicine works by inhibiting the production of prostaglandins, chemical messengers responsible for fever, swelling, and pain. It also acts on the part of the brain that controls body temperature, helping to lower fever.
You should take the Crocin Advance 500 tablet whole with a glass of water, and it may be taken with food or milk to help minimize the risk of stomach upset. The effect of the tablet generally begins to show within 30-60 minutes after consumption. It is crucial not to exceed the recommended dose, which is generally no more than 4 tablets in 24 hours for an adult with healthy liver and kidneys, and you should maintain a minimum gap of 6 hours between two consecutive doses.
While generally safe when used correctly, there is a risk of liver and kidney damage if you use paracetamol too frequently or for prolonged periods, and it is not recommended in children below 12 years of age. You must inform your doctor about any pre-existing liver or kidney conditions, or if you are taking any other medicines containing paracetamol, as this can increase the risk of side effects. If you are pregnant or breastfeeding, Crocin Advance 500 tablets can be used if your doctor recommends them, typically for a short duration and at low doses.
If your pain or fever persists after taking the medicine for 3 consecutive days, you should stop taking it and consult your doctor. Taking too much of this medicine can lead to severe liver damage, with symptoms like nausea, vomiting, loss of appetite, and stomach ache. In the event of an overdose, seek immediate medical attention.
Dolo 500mg tablet, Paracip 500mg tablet, Calpol 500mg tablet, Pyrigesic 500mg tablet and Panadol tablet are a few more medicines that also include paracetamol as their main component.,
Product Summary
| Offer Price | ₹12.38 |
| You Save | ₹4.12 (25% on MRP) |
| Contains | Paracetamol / Acetaminophen(500.0 Mg) |
| Uses | Painkiller and fever |
| Side effects | Skin rash, itching, blisters |
| Therapy | ANALGESIC/ANTIPYRETIC |
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Uses
Crocin Advance 500 tablet is an analgesic (pain reliever) and an antipyretic (fever reducer). It is used to lower fever and address mild to moderate pain. Furthermore, it relieves various discomforts, including headaches, migraines, toothaches, menstrual pain, lower back pain, muscle aches, and rheumatic pain. ...
Contraindications
- If you are allergic to paracetamol or any of the ingredients of this medicine.
- If you are taking any other medicine that contains paracetamol.
- If you have kidney or liver function problems or disease.
Side effects
There is a rare chance of side effects with Crocin Advance 500. However, in rare cases, you may experience a skin rash, itching and blisters, an allergic reaction, and blood-related problems. There is a risk of liver and kidney damage with paracetamol if used too frequently or for long-term treatment. ...
Precautions and Warnings
Pregnancy
Q:
Can I take Crocin Advance tablet during pregnancy?
A:
Crocin Advance tablet can be used during pregnancy if the doctor recommends. Yet, it should be used for a short duration in low doses and should not be used too frequently by pregnant women.
Breast Feeding
Q:
Can I take Crocin Advance tablet while breastfeeding?
A:
Paracetamol from Crocin Advance tablet passes into the breastmilk in a very small amount and has negligible effects on the breastfed infants. Thus, you can take it while you are breastfeeding.
Driving
Q:
Can I drive if I have consumed Crocin Advance tablet?
A:
Crocin Advance tablet is not likely to affect your ability to drive or use machines.
Alcohol
Q:
Can I consume alcohol with Crocin Advance tablet?
A:
Moderate consumption of alcohol when you are taking paracetamol is usually safe. However, there is a risk of liver damage if you drink alcohol too often and people with liver problems are at a risk.
Other General Warnings
Talk to your doctor if
- You have severe liver or kidney disease.
- You are an alcoholic or are suffering from chronic malnutrition.
- You are suffering from any infection or are underweight.
Directions for Use
- Take Crocin Advance 500 tablet as a whole with a glass of water.
- Do not take Crocin Advance 500 for more than three days without medical advice.
Storage and disposal
- Store Crocin Advance 500 tablet at room temperature.
- Keep it out of the reach of children.
Quick Tips
- Take the Crocin Advance 500 tablet at the exact recommended dose and do not exceed the stated dose.
- Maintain a gap of at least 4 hours between one dose and the next, and do not take more than four doses in any 24-hour period.
- Do not take Crocin Advance 500 tablets if you are already taking other medicines containing paracetamol, as taking too much paracetamol can damage the liver.
- The medicine is not recommended for children under six years of age.
- Take this medicine cautiously if you have kidney problems, as it can affect plasma creatinine concentrations.
Dosage
Overdose
- Taking Crocin Advance tablet in high doses may result in severe liver damage. Symptoms of an overdose may include nausea, vomiting, loss of appetite and stomach ache. If you happen to take too much of this medicine, then consult your doctor or reach out to the nearest hospital....
Missed a Dose
If you have missed taking a dose, then take it as soon as you remember. Keep a gap of at least 4-6 hours between this dose and the next dose. If it is almost time for the next dose, then skip the missed dose and continue with your regular dosing schedule....
Mode of Action
How Does It Work?
Crocin Advance 500 tablet works by interfering with the production of a chemical called prostaglandins, which is responsible for the fever, swelling, and sensation of pain. It also acts on the area of the brain responsible for controlling body temperature....
Interactions
Interactions with other medicines
- Certain medicines can affect the way Crocin Advance tablet works, or this tablet itself can affect the action of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbs you are taking to avoid any possible interaction.
- Before taking Crocin Advance tablet, make sure you consult your doctor if you are taking warfarin or similar medicines used to thin the blood.
- If you are taking any other medicine containing paracetamol, it may lead to an increased risk of getting side effects.
Interactions with food items
It is recommended to take Crocin Advance 500 with food or milk to minimize the risk of stomach upset.
Content Details
WRITTEN BY
Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: Is Crocin Advance a painkiller?
A: Yes, it is a painkiller effective for mild to moderate pain. It also helps reduce fever. It can be used for headaches, backache, toothache, muscle pain etc.
Q: What is Crocin 650 dosage for adults?
A: The dose, frequency and duration of taking this medicine will be decided by your doctor. An adult with a healthy liver and kidney should not take this medicine more than four times a day and should always maintain a gap of 6 hours among two doses. If your fever or pain is relieved after taking this medicine for 3 consecutive days stop taking it further.
Q: Is Crocin or paracetamol same?
A: Yes, Crocin contains paracetamol as its active ingredient. Paracetamol is a pain-relieving medicine used for relieving mild to moderate pain. It also helps reduce fever.
Q: Can I take Crocin Advance for common cold, sore throat, and fever?
A: A cold and sore throat may generally be caused by a virus. Thus, you can take Crocin Advance tablet for controlling fever but it may not be useful for treating the common cold and sore throat. Consult your doctor for advice.
Q: Can I take Crocin for arthritis or rheumatic pain?
A: Crocin is not known to be very effective in treating arthritis or rheumatic pain. Your doctor will recommend medicines to you based on your signs and symptoms. Do not self-medicate.
Q: Is Crocin good for cough?
A: Crocin tablet is a pain and fever-reducing medicine. It is not known to be used for treating cough.
Q: Can I take Crocin for nerve pain or musculoskeletal pain?
A: Crocin tablet may be suitable for providing relief from musculoskeletal pain. However, it may not be very effective in providing relief in case of nerve pain. It is recommended to ask your doctor for advice.
Q: Can Crocin Advance medicine be used in elders?
A: Kidney and liver function in the elderly is not as optimum as in the young population. Caution is needed when giving Crocin Advance tablet to the elderly with existing diseases. It should be used only after consulting your doctor. You should inform the doctor about all diseases the older person has (especially liver or kidney diseases). This will help the doctor decide the safe dose as per their age and kidney or liver function.
Q: Is Crocin Advance effective for period pain?
A: It may be effective for relieving pain during and before menstruation. Consult your doctor if you experience very severe pain during your periods, as it can be due to some other reasons.
Q: How long does Crocin 500 take to work?
A: Crocin advance starts showing its effect within 30-60 minutes, after its consumption. In case the pain persists even after taking this medicine, do not exceed the recommended dose and inform the doctor.
Q: Does Crocin advance make you sleepy?
A: No, Crocin advance does not make you sleepy. Crocin advance is an analgesic/antipyretic tablet that is entirely different from sleeping pills or medicines. However, if you feel any unusual symptoms after taking this medicine, inform the doctor.
Q: Is Dolo 650 and Crocin advance same?
A: Both medicines contain the same active ingredient, which is paracetamol, but in different doses. Dolo 650 tablet contains paracetamol 650 mg whereas Crocin Advance tablet also contains paracetamol 500 mg in it.
References
View All
- Medicine for Joint, Knee, and Muscle Pains | Muscle Ache Medicine - Crocin [Internet]. Crocin.com. 2025 [cited 27th Oct 2025]
- Acetaminophen [Internet]. Ncbi.nlm.nih.gov. 2025 [cited 27th Oct 2025]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 27th Oct 2025]
- Tripathi K. Essentials of medical pharmacology. 7th ed. Autacoids and Related Drugs: 159-210.
- Freo U, Ruocco C, Valerio A, Scagnol I, Nisoli E. Paracetamol: a review of guideline recommendations. J Clin Med. 2021;10(15):3420.
- Grosser, T., Smyth, E., & FitzGerald, G. A. (2011). Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. In J. G. Hardman, L. E. Limbird, P. B. Molinoff, R. W. Ruddon, & A. G. Gilman (Eds.), Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (12th ed., p. 693). New York: McGraw-Hill Medical.
- Paracetamol for adults: painkiller to treat aches, pains and fever [Internet]. Nhs. Uk. 2025 [cited 27th Oct 2025]
- Freo U, et al. Paracetamol: A review of guideline recommendations. J Clin Med. 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/ 2025 [cited 27th Oct 2025]
- Freo U, et al. Paracetamol: A review of guideline recommendations. J Clin Med. 2021.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/ 2025 [cited 27th Oct 2025]
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Product Details
Brand
CROCIN
Expiry Date
30/12/2026
Manufacturer Details
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