Combimist-L Respule
By ZYDUS HEALTHCARE LIMITED
5 Respule(s) in Packet
₹99.38
✱
₹132.50
25% OFF
₹19.88/respule
(Inclusive of all taxes)
✱
Offer applicable on order above ₹100015 days return policyRead More
All the Products are packed and stored Safely
Description
Combimist L respule is used to treat the symptoms of chronic obstructive pulmonary disease (COPD), such as difficulty in breathing, coughing, and wheezing. It contains a combination of ipratropium and levosalbutamol as active ingredients. This medicine works by reducing the narrowing of the smooth muscles in the airways. Combimist L respule also helps to relax the airway muscles, making breathing easier.
COPD is a chronic lung disease in which the lungs become inflamed and the airflow in and out of the lungs is reduced. This obstruction leads to symptoms like coughing, wheezing, and breathlessness.
Combimist L respule should be taken exactly as prescribed by your doctor. It should always be administered using a nebulizer, a device that converts the medicine into a fine mist so it can reach the lungs effectively. Your doctor or pharmacist will guide you on the correct use of the nebulizer.
Do not use Combimist L respule if you are allergic to any of its components. Before starting this medicine, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding, and share your complete medical history. Also, inform your doctor about all other medicines and supplements you are taking.
Product Summary
| Offer Price | ₹99.38 |
| You Save | ₹33.12 (25% on MRP) |
| Contains | Ipratropium(500.0 Mcg)+Levosalbutamol / Levalbuterol(1.25 Mg) |
| Uses | Chronic obstructive pulmonary disease (COPD) |
| Side effects | Nausea, vomiting, dry mouth, constipation, diarrhoea |
| Therapy | ANTI-ASTHMATIC, DRUGS FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE |
Uses
Combimist L respule is used to treat symptoms of COPD (chronic obstructive pulmonary disease) like breathing difficulties, coughing and whistling sounds while breathing and tightness in the chest.
Contraindications
- If you are allergic to ipratropium or levosalbutamol or any other ingredients of Combimist L respule.
- If you are allergic to atropine or its derivatives.
- If you have any problems with your heart.
- If you are below 12 years of age.
Side effects
- Nausea
- Vomiting
- Dry mouth
- Constipation
- Headache
- Dizziness
Precautions and Warnings
Pregnancy
Q:
Can I take Combimist L respule during pregnancy?
A:
There is limited information about the effects of Combimist L respule in human pregnancy.
Breast Feeding
Q:
Can I take Combimist L respule while breastfeeding?
A:
It is unknown if the components of Combimist L respule passes into human milk. Hence, you should consult your doctor before using this medicine while breastfeeding.
Driving
Q:
Can I drive if I have used Combimist L respule?
A:
There is limited information about the effects of Combimist L respule on driving but this medicine may cause dizziness and blurring of vision, you should avoid driving if you do not feel well or are unable to be alert.
Alcohol
Q:
Can I consume alcohol with Combimist L respule?
A:
Alcohol intake along with the use of Combimist L respule can make you more dizzy or drowsy. Thus, you should avoid consuming alcohol while taking this medicine.
Other General Warnings
Talk to your doctor if
- You are suffering from heart, liver or kidney problems.
- You have diabetes, glaucoma or fits.
- You have high blood pressure or an overactive thyroid gland.
- You have difficulty passing urine due to bladder problems or an enlarged prostate (mostly in men).
- You are suffering from a condition called cystic fibrosis. It increases the chances of stomach disturbances if you use Combimist L respule with it.
Directions for Use
- Combimist L respule should only be given using a nebuliser with a face mask linked to an air compressor and under the supervision of a doctor.
- Remove the pouch, open one respule, squeeze the contents into the nebulizer, and discard the respule. Your doctor will determine the appropriate dose and duration based on age, weight, and medical condition....
- Do not dilute the content, inhale it directly, or swallow it. Dispose any leftover solution and opened respules.
Storage and disposal
- Store Combimist L respule below 25°C in a clean and dry place, protected from moisture, sunlight and heat.
- Keep the medicine away from children and pets.
Quick Tips
- Clean the nebulizer after every use as per the instructions mentioned.
- It is recommended to rinse your mouth with water after inhalation of this medicine.
- You may develop oral fungal infection and an increase in wheezing after using this medicine.
- Do not stop taking Combimist L respule without consulting your doctor, even if you feel relieved after taking a few doses.
- Antifungal medicines such as Ketoconazole and Itraconazole should not be taken along with Combimist L respule.
- The chances of side effects increase significantly in the elderly population, so elderly patients should be cautious while using Combimist L respule.
- This medicine is not recommended for use in children below 12 years of age.
Dosage
Overdose
- The symptoms of overdose are headache, dry mouth, palpitation, nausea, dizziness, fatigue, fever, sleeplessness, nervousness, shakiness, restlessness, confusion, hallucinations, fits, chest pain, high or low blood pressure or irregular heartbeats....
- If you experience any of the symptoms or think you have taken too much Combimist L respule, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
Missing a dose of Combimist L respule may reduce the effectiveness of the treatment. If you forget a dose, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose....
Mode of Action
How Does It Work?
COPD is a common lung problem that causes damage over time, leading to long-term coughing with mucous and breathing difficulties. Combimist L respule works by using Ipratropium to block certain substances and decrease the tightness of breathing tubes, making breathing easier, while Salbutamol relaxes the muscles of the smaller lung tubes....
Interactions
Interactions with other medicines
- Concomitant use of Combimist L respule along with medicines used to treat psychiatric illness (e.g., Amitriptyline, selegiline) or medicines used to treat asthma (e.g., Albuterol, Epinephrine) should be avoided as it may alter the effects of this medicine....
- Concomitant use of this medicine with beta-blockers like Propranolol, Labetalol, etc. (used to treat high blood pressure and heart problems) may decrease the effectiveness of Combimist L respule.
- Concomitant use of this medicine with water pills like Furosemide and hydrochlorothiazide may decrease the potassium level in the body, which can lead to heart rhythm abnormalities. Your doctor may advise monitoring the blood potassium level....
- Other medicines like Digoxin (used to treat heart problems) and xanthine preparations like Theophylline (used in asthma) should be used cautiously.
Interactions with food items
It is advised to take Combimist L respule on an empty stomach.
Content Details
WRITTEN BY
Ravindra Ghongade
B. Pharm
REVIEWED BY
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: What is Combimist L respule used for?
A: Combimist L respule are used to treat Chronic Obstructive Pulmonary Disorder (COPD) and its symptoms like sneezing, coughing, difficulty in breathing, chest tightness, etc.
Q: I am taking medicines for diabetes, can I use Combimist L respule?
A: Combimist L respule may alter the blood glucose level in the body. If you have diabetes, tell your doctor before starting the treatment.
Q: Can I stop taking Combimist L respule on my own?
A: No, you should never stop taking Combimist L respule until advised by the doctor, even if you are feeling good as it may lead to treatment failure.
Q: Can I give Combimist L respule to my son, who is 10 years old?
A: No, Combimist L respule should not be given to children below the age of 12 years. You should never self-prescribe any medicine on your own without consulting a doctor.
Q: Is Combimist L respule habit-forming?
A: No, Combimist L respule is not habit-forming. However, it should be used as per the dose and duration prescribed by your doctor.
Q: Does Combimist L respule provide immediate relief in a sudden acute asthma attack?
A: No, it is not used to relieve sudden breathing problems. You should always keep your rescue inhaler readily available if sudden shortness of breath occurs.
Q: Does Combimist L respule have any side effects?
A: Dry mouth, constipation, nausea and headache are a few common side effects of Combimist L respule. If these symptoms last for a long, inform your doctor immediately.
Q: How long can Combimist L respule be used?
A: You can use Combimist L respule for as long as a doctor has recommended you. Combimist L respule is indicated for the maintenance treatment of asthma, so you must take it exactly as instructed by your doctor. The doctor decides the maintenance dose and duration based on the patient's underlying condition and prescribes the lowest effective dose which keeps the patient symptom-free.
Q: How often can you use Combimist L respule?
A: You should use Combimist L respule is often advised by the doctor. Do not exceed the recommended dose. However, the total number of respules should not exceed 3 in 24 hours in every 6-8 hours, unless told by the doctor.
Q: How do you use Combimist L respule?
A: Combimist L respule should be used in the exact dose and frequency advised by your doctor. Check it with your doctor or pharmacist if you are not sure.
Q: Does Combimist L respule contain steroids?
A: No, this medicine does not contain steroids. It contains Ipratropium and Levosalbutamol which relaxes the muscles of the airways in the lungs.
Q: Will Combimist L respule be more effective if taken in higher doses?
A: No, you should not take Combimist L respule at higher doses than the recommended dose. It will increase the risk of side effects rather than provide additional therapeutic benefits. However, if you feel the symptoms are not relieved by the recommended doses, please consult the doctor for re-evaluation.
Q: Can Combimist L respule be used for cough?
A: Yes, Combimist L respule can be used for the treatment of coughing that is associated with COPD (chronic obstructive pulmonary disease).
Q: Are Combimist L respule suitable for adults?
A: Yes, Combimist L respule are commonly prescribed for adults with asthma, COPD, or other breathing problems involving airway tightening. It helps open the airways and provides relief from shortness of breath and wheezing. Adults should use it only in the dose advised by their doctor. Overuse can lead to side effects like tremors or a fast heartbeat. Always follow medical advice for safe and effective use.
References
View All
- DrugBank. Ipratropium [Internet]. 2025 [cited 30 Jan 2026]
- DrugBank. Levosalbutamol. [Internet]. 2025 [cited 30 Jan 2026]
- Koc Z, Bilgic S, Koc Y, et al. Levosalbutamol. Clin Cardiol. 2007 Apr;30(4):187-92. doi: 10.1002/clc 20143. PMID: 17337829. 2025 [cited 30 Jan 2026]
- ScienceDirect. Levosalbutamol. ScienceDirect. 2025 [cited 30 Jan 2026]
- CDSCO [Internet]. Cdscoonline.gov.in. 2025 [cited 30 Jan 2026]
- MedlinePlus. Ipratropium [Internet]. U.S. National Library of Medicine; 2025 [cited 30 Jan 2026]
Did you find this medicine information helpful?
Please rate your experience
Product Details
Brand
COMBIMIST
Address
Axa Parenterals Ltd. Plot No. 936, 937 & 939, Kishanpur Jamalpur, Roorkee-247667, Uttarakhand, INDIA
Country of Origin
India
Expiry Date
30/03/2027
Manufacturer Details
Blog Articles
Chronic Condition Articles
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
Please add item(s) to proceed
