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Colicure Plus Tablets (Marc)

10 Tablet(s) in Strip
MRP 48.40
41.1415% OFF
Inclusive of all taxes
7 days return policyRead More
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Colicure Plus Tablets (Marc) Description

Colicure Plus Tablet is used to provide relief from muscle spasms and pain associated with various conditions. It is a combination of medicine containing drotaverine and mefenamic acid as an active i

ngredient. This medicine works by the combined action of both ingredients. Drotaverine is an anti-spasmodic medicine that helps in relieving spasms, and mefenamic acid has anti-inflammatory that helps to relieve pain. You should not take this medicine if you recently had a heart attack, before bypass surgery of heart or if you have or ever had an ulcer in the stomach or intestine. Taking this medicine longer than the prescribed duration or taking it too often may cause undesirable effects. Take this medicine as advised by your doctor. You should take a Colicure Plus Tablet with meals to reduce stomach upset.


Product Summary

Offer Price₹41.14
You Save₹7.26 (15% on MRP)
ContainsDrotaverine(80.0 Mg) + Mefenamic Acid(250.0 Mg)
UsesPain and spasm
Side effectsNausea, vomiting, diarrhoea, dry mouth
Check more medicines with composition as Drotaverine(80.0 Mg) + Mefenamic Acid(250.0 Mg)

Uses of Colicure Plus Tablets (Marc)

Colicure Plus Tablet is used for the treatment of menstrual cramps, stomach pain, and muscle spasms. It may be useful in pain due to bowel disorders, after surgery and due to kidney stones.

Contraindications of Colicure Plus Tablets (Marc)

  • If you are allergic to mefenamic acid, drotaverine or any of the ingredients of Colicure Plus Tablet.
  • If you have a kidney or liver function problem, history of asthma or stomach or intestinal ulcers.
  • If you have any blood-related disorders like unusual bleeding and porphyria (related to haemoglobin function).
  • If you had a heart attack recently, undergoing a coronary artery bypass graft. Do not take this medicine right before the surgery or after the surgery without consulting a doctor.

Side effects of Colicure Plus Tablets (Marc)

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dryness in mouth
  • Thirsty feeling
  • Itching
  • Rashes

Precautions and Warnings of Colicure Plus Tablets (Marc)



Can I take Colicure Plus Tablet during pregnancy?
There is limited information available on the safety of Colicure Plus in pregnancy. Thus, it is advised to consult your doctor before taking this medicine, if you are pregnant. Your doctor will tell you about the use of this medicine after assessing the need and may prescribe you only if the benefits to the mother outweighs the risk to the foetus.

Breast Feeding

Can I take Colicure Plus Tablet while breastfeeding?
It is advised not to breastfeed if you are taking a Colicure Plus Tablet, as there is limited information available about its effect on the newborn baby. Thus, avoid using this medicine unless advised by your doctor after assessing the need and benefits.


Can I drive if I have consumed Colicure Plus Tablet?
Colicure Plus can cause dizziness, drowsiness, tiredness, visual disturbance, etc. It would be better if you do no drive or operate any machinery when you are taking this medicine.


Can I consume alcohol with Colicure Plus Tablet?
Try to avoid alcohol intake along with this medicine. It may worsen the side effects, and it can also make you dizzier.

Other General Warnings

Talk to your doctor if
  • You are an elderly person, the chances of getting side effects are more.
  • You have a history of any kind of respiratory disorders like asthma.
  • You have a liver or kidney function problem.
  • You are suffering from fits, tremors or epilepsy.
  • You have a heart-related problem or high blood pressure.
  • You have a history of heart failure or such episodes.
  • You are suffering from ulcers or bleeding in the stomach or intestine.
  • You experience allergic reactions upon consumption of Colicure Plus.
  • Women may experience infertility. Thus, women who are trying to conceive or taking any fertility treatment should avoid consuming this medicine.

Mode of Action of Colicure Plus Tablets (Marc)

How Does It Work?

  • Pain and spasm are experienced due to the production of an inflammatory mediator called prostaglandin and due to reduced calcium levels. Colicure Plus helps in relieving such symptoms due to the combi...
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  • Drotaverine acts by inhibiting an enzyme which reduces calcium uptake by the cells, thereby correcting the calcium levels in the body it reduces the spasms in the smooth muscles. Mefenamic acid inhibi...
    Read more

Directions for Use of Colicure Plus Tablets (Marc)

Take Colicure Plus Tablet as directed by your doctor with a sufficient amount of water.

Interactions of Colicure Plus Tablets (Marc)

Interactions with other medicines

  • Certain medicines can affect the way Colicure Plus works or Colicure Plus itself can affect the action of other medicines taken at the same time.
  • Concomitant use of medicines used to treat blood pressure like Aliskiren, Captopril and Valsartan should be avoided.
  • Blood thinners such as Warfarin should be used cautiously with Colicure Plus as there is increased risk of bleeding.
  • Colicure Plus should not be taken along with other pain killers or analgesic medicines.
  • Colicure Plus can aggravate the blood-glucose-lowering action of anti-diabetic medicines, and you may experience symptoms of low blood sugar.
  • Water pills, Cyclosporin, and Tacrolimus if taken along with Colicure Plus can increase the risk of toxicity to kidneys.
  • There is an increased risk of bleeding and ulceration if Colicure Plus is taken along with steroids and certain medicines used for mental illness.
  • Other medicines like Prednisone, Methotrexate, Fluconazole, Zidovudine, Digoxin, Probenecid, and certain antibiotics should be used cautiously.

Storage and disposal of Colicure Plus Tablets (Marc)

  • Store at room temperature in a cool and dry place.
  • Keep this medicine out of the reach of children and pets.

Dosage of Colicure Plus Tablets (Marc)


If you think you have taken an excessive dose of Colicure Plus, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Do not take a double dose if you have missed the dose; take the next dose as soon as you remember. If it's already time for your next dose, skip the missed dose and follow your normal dosing schedule.

Content Details


Dr. Mansi Savla

B. Pharm, PharmD


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Any precautions do I need to take after taking this medicine?

A: If you have a history of low blood pressure, your doctor may ask you for regular blood pressure checkups because this medicine can cause a sudden drop in blood pressure.

Q: Can Colicure Plus be used for menstrual cramps?

A: Yes, it is helpful in relieving spasm and cramps associated with periods. However, for prolonged and painful episodes consult your doctor.

Q: Can I take Colicure Plus while breastfeeding?

A: No, constituents of Colicure Plus may pass into breast milk and can affect the breastfed baby. Avoid using this medicine while breastfeeding.

Q: Can we take Colicure Plus in an empty stomach?

A: No, you should take a Colicure Plus Tablet with food or after your meals to avoid any stomach discomforts.

Q: How long does it take for Colicure Plus to show its effect?

A: This medicine usually starts working within an hour. However, it can vary among individuals depending on their physiology and other biological parameters.

Q: How many times Colicure Plus can be taken in a day?

A: It should be taken as per the need or as advised by the doctor. The dose can vary depending on the severity of the condition. However, do not take it more often or more than recommended dose and duration.
Product Details
Expires on or After
Last Updated on: 12 May 2022 | 01:11 PM (IST)
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