Acemiz-S Tablet
Description
Acemiz-S Tablet is a combination medicine commonly prescribed to relieve pain, swelling, and inflammation affecting the joints, bones, and muscles. It is particularly useful in conditions such as arthritis, muscle injuries, sprains, back pain, and post-surgical pain. This tablet contains three active ingredients: Aceclofenac (a non-steroidal anti-inflammatory drug), Paracetamol (a pain reliever and fever reducer), and Serratiopeptidase (an enzyme that reduces inflammation and swelling). Together, they provide effective relief from pain and improve mobility.
The medicine works by blocking chemical messengers in the body that cause pain, fever, and inflammation. Aceclofenac and Paracetamol help reduce pain and lower fever, while Serratiopeptidase enhances healing by reducing swelling and tissue damage. This makes Acemiz-S Tablet a preferred choice for patients suffering from painful musculoskeletal and joint conditions.
It should be taken exactly as prescribed by your doctor, in the recommended dose and duration. To minimise stomach irritation, it is advised to take Acemiz-S Tablet with food or immediately after meals. Never take this medicine on an empty stomach, as it may increase the risk of acidity or gastric discomfort.
Some patients may experience common side effects such as nausea, stomach upset, indigestion, or dizziness. These side effects are usually mild and temporary. However, if symptoms persist or you develop severe symptoms, such as stomach pain, black stools, or signs of an allergic reaction, seek immediate medical attention. It is also important not to exceed the recommended dosage, as it may cause liver or kidney problems.
Before starting treatment with Acemiz-S Tablet, inform your doctor about your complete medical history, especially if you have liver disease, kidney disease, stomach ulcers, asthma, or high blood pressure. Pregnant and breastfeeding women should use this medicine only under medical supervision. With proper use, Acemiz-S Tablet can provide effective relief from pain and inflammation, improving your daily comfort and quality of life.
Product Summary
Offer Price | ₹82.39 |
You Save | ₹57.26 (41% on MRP) |
Contains | Aceclofenac(100.0 Mg)+Serratiopeptidase(15.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) |
Uses | Pain relief |
Side effects | Nausea, vomiting, stomach upset |
Therapy | ANALGESIC/ANTIPYRETIC |
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Uses
Contraindications
- If you are allergic to paracetamol, aceclofenac, serratiopeptidase or other ingredients of Acemiz-S tablet.
- If you suffer from allergy including asthma, skin rashes or a runny nose after taking medicines like Ibuprofen and Aspirin.
- If you suffer from allergic reactions.
- If you suffer from stomach ulcers or bleeding.
- If you suffer from heart diseases like heart failure and high blood pressure.
- If you suffer from kidney and liver functions.
- If you are pregnant (especially after the 3rd month of pregnancy).
Side effects
- Nausea
- Vomiting
- Indigestion
- Stomach pain
- Constipation
- Diarrhoea
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have kidney or liver problems.
- You have heart problems like high blood pressure, heart failure.
- You are an elderly patient or taking diuretics or have a kidney disorder, the medicine increases the risk of kidney failure. The doctor may ask to perform renal function tests for the same.
- You suffer from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease or you notice black tarry stools.
- You suffer from asthma as the medicine worsen the same.
- You have SLE (an autoimmune disorder).
- You are an alcoholic and the concomitant use of the medicine damages the liver.
- You suffer from disorders related to blood like clotting problems and anaemia.
- You develop skin rashes and lesions after taking the Acemiz-S tablet.
- You are pregnant, planning a pregnancy or are breastfeeding.
- Avoid taking other medicine containing Paracetamol along with the medicine.
Directions for Use
Storage and disposal
- Store at a cool and dry place protected from moisture.
- Keep it away from children.
Quick Tips
- Take Acemiz-S Tablet after meals to avoid stomach upset.
- Always use it in the exact dose and duration prescribed by your doctor.
- Drink plenty of water while on this medicine.
- Avoid alcohol, as it can increase the risk of stomach and liver problems.
- Do not combine it with other painkillers unless advised by your doctor.
- Prolonged use can harm the liver and kidneys, so avoid self-medication.
- Store the tablet in a cool, dry place away from children.
- Pregnant and breastfeeding women should use it only if prescribed by a doctor.
- If you notice severe stomach pain, black stools, yellowing of skin or eyes, or unusual fatigue, stop taking it and consult your doctor immediately.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Acemiz-S tablet works by the combined action of the three components - aceclofenac, paracetamol and serratiopeptidase.
- Aceclofenac and paracetamol interfere with the production of a chemical substance called prostaglandin which is responsible for swelling and pain.
- Serratiopeptidase repairs the tissues and decrease the swelling around the infected area.
Interactions
Interactions with other medicines
- Acemiz-S tablet may interact with other medicines, discuss with the doctor regarding the medicines, supplements or herbal preparations you are taking. Discuss with the doctor if you have a planned surgery or vaccination schedule....
- Avoid using other medicines containing Paracetamol or Aceclofenac as there is a risk of liver damage.
- If you are taking medicines for high blood pressure, the medicine interferes with the effect.
- Medicines like a water pill lead to kidney damage when taken along with it.
- Caution is needed if you are using medicines to treat heart failure.
- Medicines used to modify immune response during organ transplants like cyclosporin and tacrolimus results in kidney damage if taken with the medicine.
- It increases the risk of stomach ulcers or bleeding when taken with steroids or other pain-relief medicines like Aspirin.
- There is a risk of bleeding if you are using blood-thinning medicines like Warfarin and Coumarin.
- An increased risk of fits if you are taking the medicine with antibiotics like Levofloxacin and Ciprofloxacin.
- If you are using medicines to treat diabetes, be cautious about the symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs.
- Medicines used to treat fits, seizures and depression-like Phenobarbital, Carbamazepine, Phenytoin and Clonazepam, a medicine used to treat gout like Probenecid, medicines used to treat bacterial infections like Chloramphenicol, Rifampicin and HIV infections like Zidovudine must be used with caution....
Content Details

Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What precautions must I follow before taking the Acemiz-S tablet being diabetic?
Q: Can I take my regular painkillers along with Acemiz S tablet?
Q: I am using the Acemiz-S tablet for a long time, do I need to perform tests?
Q: Is the Acemiz-S tablet useful for a headache?
Q: Can the Acemiz-S tablet be taken for a toothache?
Q: When should I take Acemiz S Tablet?
Q: What is Acemiz-S used for?
Q: Can Acemiz-S Tablet cause acidity or gastric problems?
Q: Is Acemiz-S Tablet safe for elderly patients?
References
- VOLTANEC SP tablets (Aceclofenac + Paracetamol + Serratiopeptidase) [Internet]. Ciplamed.com. 2021 [cited 11 March 2022]
- CDSCO. Acelofenac-Paracetamol-Serratiopeptidase [Internet]. Cdscoonline.gov.in. 2021 [cited 11 March 2022]
- LactMed. Acelofenac-Paracetamol-Serratiopeptidase [Internet]. Ncbi.nlm.nih.gov. 2021 [cited 11 March 2022]
- Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [cited 09 Sep 2025].
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