Zerodol SP Tablet

10 Tablet(s) in Strip

MRP ₹139.69

₹101.97

27% OFF

₹10.2/tablet (Inclusive of all taxes)

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Made by

IPCA LABORATORIES

Dosage

TABLET

Expiry

December 2027

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Product Summary

Salt Content	Aceclofenac(100.0 Mg)+Serratiopeptidase(15.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg)
Uses	Muscle pain, Joint pain, Swelling, and Inflammation
Therapy	Analgesic/antipyretic, anti-inflammatory
Side effects	Stomach pain, constipation, diarrhoea, bloating, stomach ulcers

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Medical Description

Zerodol-SP is used to treat pain (moderate to severe). It also helps in treating pain that is accompanied by swelling and inflammation. Zerodol-SP is a combination medicine used to relieve throbbing toothaches, painful joints, or swelling after an injury from three different aspects. This medicine provides fast-acting relief.

Zerodol-SP is a prescription painkiller. It contains aceclofenac, paracetamol, and serratiopeptidase as its main ingredients. Aceclofenac and paracetamol are painkillers, and serratiopeptidase is an enzyme that breaks down the substances that cause swelling and promotes faster healing.

The most common side effects of Zerodol-SP are related to the stomach, such as nausea, indigestion, stomach pain, and diarrhoea. To avoid these issues, it is important to always take the tablet with food or a glass of milk. You should never take this medicine on an empty stomach. Avoid drinking alcohol while taking Zerodol-SP, as this can severely increase your risk of stomach bleeding and liver damage.

The usual dose for adults is one tablet, once or twice a day, as prescribed by a doctor. You should never take more than the recommended dose. Zerodol-SP is intended for short-term use only. If you have a history of stomach ulcers, kidney or liver problems, or if you are pregnant or breastfeeding, you must consult your doctor before taking this medicine. If your pain does not improve after a few days, stop taking the tablet and seek medical advice.

Uses

The Zerodol-SP tablet is a medication used to treat pain associated with inflammation and swelling. Here are the main uses of the Zerodol-SP tablet.

For tooth Pain and toothache: When you have a toothache, the pain is often caused by inflammation in the gums or the tooth's pulp. Zerodol-SP for tooth pain works because aceclofenac and paracetamol block the pain signals, while Serratiopeptidase reduces the gum swelling, providing complete relief from the throbbing pain and discomfort.
Relief from Joint Pain (Osteoarthritis & Rheumatoid Arthritis): Zerodol-SP is widely prescribed to manage the pain and inflammation associated with joint conditions. In osteoarthritis, it helps relieve the pain from cartilage wear and tear. In rheumatoid arthritis, it helps reduce the painful swelling and stiffness in the joints caused by the body's immune system attacking them.
Back Pain, Neck Pain, and Spondylitis: For conditions such as lower back pain, a stiff neck, or ankylosing spondylitis, Zerodol-SP provides relief by reducing inflammation in the spine and relaxing the muscles.
Post-Surgical Pain and Swelling: After a minor surgery or a dental procedure, the body's natural response is to create inflammation and swelling at the site. The Serratiopeptidase in Zerodol-SP helps to clear away the excess fluid and proteins, reducing swelling and bruising, which in turn speeds up the healing process.
Pain from Injuries (Sprains and Strains): For sports injuries, sprains, or muscle strains, Zerodol-SP works to alleviate the immediate pain, control the inflammation, and reduce the swelling, helping you recover more comfortably.

Contraindications

If you have a known allergy or hypersensitivity to aceclofenac, paracetamol, serratiopeptidase, aspirin, or any other NSAIDs (like Ibuprofen), or any of the ingredients of this medicine.
If you have a history of asthma attacks, severe skin rashes, or allergic reactions after taking other painkillers.
If you have an active or a history of frequent stomach ulcers, or have experienced bleeding or perforation in any part of your digestive system, stomach, or intestines.
If you are in your third trimester of pregnancy.
If you suffer from severe heart failure, liver disease, or kidney disease.

Side effects

Common Side Effects (usually mild)

Nausea, vomiting, or diarrhoea
Stomach pain
Indigestion
Heartburn
Loss of appetite
Dizziness or headache

Serious Side Effects (rare, but require immediate medical attention)

Severe allergic reactions such as rashes, hives, difficulty breathing, or swelling of the face, lips, tongue, or throat
Bleeding in the stomach
Black, tarry, or bloody stools
Coughing up blood or vomit that looks like coffee grounds
Chest Pain
Weakness
Shortness of Breath
Jaundice (yellowing of skin or eyes)
Difficulty urinating
Bloody urine
Blistering, peeling, or a purple skin rash (e.g., Stevens-Johnson Syndrome)

Precautions and Warnings

Pregnancy

No, it is not safe to take Zerodol-SP tablet during pregnancy, especially in the last three months, as it can harm the developing baby and cause complications during delivery. Always consult your gynaecologist before taking any painkillers during pregnancy.

Breast Feeding

It is generally not recommended to use Zerodol-SP while breastfeeding, as the ingredients can pass into breast milk. It is best to consult your doctor, who can suggest a safer alternative for pain relief.

Driving

It is best to avoid driving after taking Zerodol-SP. While it doesn't typically cause severe drowsiness, a possible side effect is dizziness, which could impair your ability to drive safely.

Alcohol

You should strictly avoid consuming alcohol while taking Zerodol-SP. Combining alcohol with NSAIDs like Aceclofenac and Paracetamol significantly increases the risk of stomach bleeding, ulcers, and severe liver damage.

Other General Warnings

Talk to your doctor if

You have a history of liver, kidney, or heart conditions.
You have high blood pressure, asthma, or any bleeding disorders.
You have a history of stomach ulcers, acidity, or inflammatory bowel disease (like Crohn's disease).
You are scheduled for any surgery, including dental surgery.

Directions for Use

The standard dose of Zerodol-SP tablet is one tablet. Take it once or twice a day as prescribed by your doctor.
Always take this medicine with food and a full glass of water. This is crucial for protecting your stomach lining from irritation.
Swallow the tablet whole. Do not crush, chew, or break it, as this can affect how the medicine is released into your body.
Maintain a consistent time gap between doses as advised by your doctor.
Use this medicine for the shortest duration necessary to control your symptoms. Do not use it for long-term pain without medical supervision.

Storage and disposal

Store Zerodol-SP tablets in a cool, dry place at room temperature (below 30°C).
Keep the medicine in its original strip or container to protect it from direct sunlight and moisture.
Always ensure the tablets are stored out of the reach and sight of children and pets.
Do not use the tablets after the expiry date printed on the packaging.
Dispose of any expired or unused medicine responsibly.

Quick Tips

Always take Zerodol-SP tablet with a meal or a glass of milk to prevent stomach upset and reduce the risk of ulcers.
Never take Zerodol-SP with other painkillers containing paracetamol or other NSAIDs (like Ibuprofen), as this can lead to an overdose and serious side effects.
Avoid drinking alcohol while on Zerodol-SP tablet to protect your stomach and liver.
Zerodol-SP is very effective for toothaches, but it only treats the symptoms, not the underlying cause. You should see a dentist to address the underlying dental issue.
If you are taking this medicine for more than a few days, your doctor may want to monitor your kidney and liver function.
Zerodol SP can be used to treat the pain, inflammation, and fever associated with tonsillitis; however, it is a prescription medication that should be taken only as directed by a physician. It is not an antibiotic and will not treat an underlying bacterial infection if present.
Zerodol SP should be taken exactly as prescribed by your doctor at the recommended best time for you (morning, afternoon, or night). It may be taken on an empty stomach, before food, or after/meal, as advised. Ensure you follow your routine and complete the full course. Your doctor provides the schedule to ensure the medicine works effectively.

Doctor’s suggestion

Ravindra GhongadeB. Pharm

Zerodol-SP Tablet is commonly used to relieve pain, inflammation, and swelling associated with conditions like muscle injuries, joint pain, arthritis, dental pain, and post-surgical inflammation. It contains a combination of aceclofenac, paracetamol, and serratiopeptidase, which work together to reduce pain, control inflammation, and help decrease swelling in affected tissues. While it can provide effective short-term relief, it should be taken only as prescribed because prolonged or excessive use may increase the risk of stomach irritation or other side effects. If pain or swelling persists for several days, it is advisable to consult a doctor rather than continuing self-medication.

Dosage

Overdose

An overdose of Zerodol-SP can be dangerous, primarily due to the high doses of aceclofenac and Paracetamol. Symptoms can include severe stomach pain, nausea, vomiting, drowsiness, and in serious cases, liver or kidney damage. If you suspect an overdose, seek immediate medical attention or go to the nearest hospital emergency room.

Missed a Dose

If you miss a dose of Zerodol-SP, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose. Do not take a double dose to make up for the one you forgot, as this increases the risk of side effects.

Mode of Action

How Does It Work?

The Zerodol-SP tablet works by combining three powerful ingredients to fight pain and swelling from multiple angles. It doesn't just mask the pain, but actively addresses the root cause for faster relief and healing.
Aceclofenac is a key anti-inflammatory ingredient. It works by blocking certain chemicals in your body that are responsible for creating pain and inflammation signals. By stopping these "pain messengers" at their source, Aceclofenac effectively reduces the redness, warmth, and swelling associated with injuries or conditions like arthritis.
Paracetamol is a trusted pain reliever that works mainly in your brain. While Aceclofenac fights pain at the site of the injury, Paracetamol blocks the pain signals from reaching your brain, which lowers your perception of pain. This dual-action approach provides more comprehensive pain relief and is also very effective at reducing fever.
Serratiopeptidase is a unique enzyme that helps clean up the mess left behind by an injury. When tissues are damaged, your body can produce a lot of protein debris that causes swelling. Serratiopeptidase breaks down this debris, allowing the trapped fluid to drain away and reducing the pressure and swelling. This speeds up the entire healing process.
Together, these three ingredients provide powerful relief by blocking pain signals, reducing inflammation, and actively cleaning up the debris that causes swelling.

Interactions

Interactions with other drugs

Effect

Co-administration can reduce renal clearance of lithium, leading to elevated plasma lithium levels and increased risk of toxicity.

Advice

Monitor carefully for signs of lithium toxicity. Frequent monitoring of serum lithium levels is recommended.

Effect

Synergistic effects can significantly increase the risk of gastrointestinal bleeding and prolong prothrombin time.

Advice

Use with extreme caution. Close monitoring of coagulation indices (INR) and strict surveillance for unusual bleeding is required.

Effect

Co-administration may increase the risk of severe hepatotoxicity, particularly with high doses or prolonged use of paracetamol.

Advice

Use with caution. Monitor liver function tests closely and observe for signs of hepatic injury (e.g., jaundice, dark urine).

Effect

Co-administration may enhance the risk of severe nephrotoxicity associated with ciclosporin due to reduced renal prostacyclin synthesis.

Advice

Use with caution. Baseline and regular follow-up monitoring of renal function is highly recommended.

Effect

Concurrent use of NSAIDs with quinolone antibiotics may increase the risk of developing central nervous system stimulation and convulsions.

Advice

Use cautiously. Monitor patients closely for neurological side effects or signs of seizures, particularly in those with a history of epilepsy.

Effect

Interference with platelet function combined with NSAID use significantly increases the risk of serious gastrointestinal ulceration or bleeding.

Advice

Avoid concurrent use if possible. Monitor closely for signs of GI bleeding, such as melena or hematemesis.

Effect

Co-administration can diminish the diuretic and antihypertensive effects, and may increase the risk of nephrotoxicity.

Advice

Monitor blood pressure and renal function closely. Ensure adequate hydration.

Effect

NSAIDs may exacerbate cardiac failure, reduce glomerular filtration rate, and increase plasma digoxin levels.

Advice

Use with caution. Regular monitoring of serum digoxin levels and cardiac function is advised.

Effect

Metoclopramide accelerates gastric emptying, which increases the rate of absorption of paracetamol and leads to a faster peak plasma concentration.

Advice

Concomitant use is generally considered safe. No specific clinical intervention is required.

Effect

Cholestyramine reduces the gastrointestinal absorption of paracetamol, potentially diminishing its analgesic and antipyretic efficacy.

Advice

Administer paracetamol at least 1 hour before or 4 to 6 hours after cholestyramine administration.

Frequently Asked Questions (FAQs)

The main uses of the Zerodol-SP tablet are to relieve pain, inflammation, and swelling associated with conditions like arthritis, spondylitis, and injuries. It is also highly effective for post-surgical pain and severe tooth pain.

Yes, Zerodol-SP is a painkiller. Its triple-action formula with aceclofenac, paracetamol, and serratiopeptidase makes it more effective than a simple painkiller.

Zerodol-SP is extremely effective for tooth pain and toothache, as it tackles all aspects of dental pain. It blocks pain signals, reduces gum inflammation, and the serratiopeptidase helps alleviate painful swelling.

The Zerodol-SP composition is a combination of three medicines - Aceclofenac (100 mg), a strong anti-inflammatory painkiller; Paracetamol (325 mg), a pain and fever reducer; and Serratiopeptidase (15 mg), an enzyme that reduces swelling.

The most common Zerodol-SP side effects are related to the stomach, such as nausea, indigestion, stomach pain, and diarrhoea. Taking the tablet with food is the best way to minimize these effects.

No, you should never take more than the dose prescribed by your doctor. Taking two tablets at once can significantly increase your risk of serious side effects, especially stomach bleeding and liver damage.

You should start to feel relief from pain within about an hour of taking a Zerodol-SP tablet. The full effect on swelling may take a little longer as the serratiopeptidase begins to work.

No, Zerodol-SP is not an antibiotic. It is a painkiller and anti-inflammatory medicine. It does not treat bacterial infections. However, by reducing swelling, it can sometimes help antibiotics work better.

Yes, you can use Zerodol-SP tablet for headaches. It is a potent medicine specifically designed to alleviate pain associated with inflammation.

The Zerodol-SP price in India is quite affordable. You can get the Zerodol-SP tablet at the best offer price on PharmEasy. To see the most current cost, please check the price details at the top of this page. We regularly provide exciting offers and discounts, so you always get the best value with us.

Zerodol SP and Joydol P both contain aceclofenac, paracetamol, and serratiopeptidase. You should only take the medicine prescribed by your doctor, as the same shall be based on your diagnosis and medical conditions. Avoid self-medication.

Zerodol SP contains aceclofenac, paracetamol, and serratiopeptidase, while Zerodol P contains aceclofenac and paracetamol. Always take medication as prescribed by your physician, as it is based on your diagnosis and medical conditions. Avoid self-medication.

Signoflam and Zerodol SP both contain aceclofenac, paracetamol, and serratiopeptidase. You should only take the medicine prescribed by your doctor, as the same shall be based on your diagnosis and medical conditions. Avoid self-medication.

Zerodol-SP contains aceclofenac, while Enzoflam contains diclofenac. Both also contain paracetamol and serratiopeptidase. You should only take the medicine prescribed by your doctor, as the same shall be based on your diagnosis and medical conditions. Avoid self-medication.

Zerodol SP is primarily used to relieve pain, swelling, and inflammation and may be prescribed for short-term pain relief in conditions such as hemorrhoids or anal fissure when pain and swelling are significant; however, it does not treat the underlying cause. It may also reduce pain and inflammation associated with boils, but antibiotics or local treatment are usually required. Zerodol SP should not be used for eye infections or blood clots, as these need specific medical treatment. In viral fever, it may help relieve body pain and inflammation, but should be used cautiously and only for a short duration. Always consult your doctor before using Zerodol SP to ensure it is appropriate and safe for your condition.

Zerodol-SP combines three ingredients to relieve pain, inflammation, and swelling, while Zerodol-CR contains a single ingredient in a controlled-release formulation for long-lasting relief. You should only take the medicine prescribed by your doctor, as the same shall be based on your diagnosis and medical conditions. Avoid self-medication.

No. Zerodol SP is a pain‑relief and anti‑inflammatory medicine and does not treat blood clots.

Yes, Zerodol SP may be used to relieve moderate to severe menstrual pain (dysmenorrhea). It helps reduce pain and inflammation associated with uterine cramps. However, it should be used only for short periods and as advised by your doctor. Do not self‑medicate for period pain. If cramps are severe or recurrent, consult your doctor to rule out underlying conditions.

Zerodol SP can help reduce pain and inflammation caused by kidney stones, but it does not treat or remove the stone itself. Doctors may prescribe it for temporary pain relief along with other medicines. Long‑term or unsupervised use is not recommended as it may affect the stomach or kidneys. Adequate hydration and proper medical evaluation are essential. Always follow your doctor’s advice.

Zerodol SP may help relieve pain and inflammation associated with sciatica, especially when muscle spasm or swelling is involved. However, it is not a specific medicine for nerve pain. Your physician may recommend additional medications or physiotherapy. Consult your doctor for the most suitable treatment plan.

Yes, Zerodol SP is used for pain and swelling due to injury, arthritis, or joint conditions such as knee pain or a swollen finger when prescribed by a physician. It helps reduce inflammation and provides pain relief. It should be taken for the shortest duration needed. Avoid prolonged use without medical advice, especially if you have stomach, liver, or kidney problems. Always consult your doctor if swelling persists.

Zerodol SP can help relieve pain or discomfort associated with a urinary tract infection (UTI), but it does not treat the infection. Antibiotics are required to cure a UTI. Using Zerodol SP alone may mask symptoms and delay proper treatment. Always consult a physician for an accurate diagnosis and appropriate antibiotics. Take Zerodol SP only if prescribed.

Zerodol-SP contains aceclofenac, while Diclogesic-SP contains diclofenac. Both also contain paracetamol and serratiopeptidase. You should only take the medicine prescribed by your doctor, as the same shall be based on your diagnosis and medical conditions. Avoid self-medication.

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Manufacturer Details

Brand:ZERODOL SP

Manufacturer Name:IPCA LABORATORIES

Address:Ipca Laboratories Ltd.,393/394, Melli. Jorethang Road,,Gom Block, Bharikhola,,South District, Sikkim-737121

Country of Origin:India

Vendor Details

Fulfillment Information: Zerodol Sp Strip Of 10 Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.

Zerodol SP Tablet

Product Summary

Medical Description

Uses

Contraindications

Side effects

Precautions and Warnings

Pregnancy

Breast Feeding

Driving

Alcohol

Other General Warnings

Directions for Use

Storage and disposal

Quick Tips

Doctor’s suggestion

Dosage

Overdose

Missed a Dose

Mode of Action

How Does It Work?

Interactions

Interactions with other drugs

Frequently Asked Questions (FAQs)

Articles

Chronic Condition Articles

Did you find this helpful?

Explore More at Pharmeasy

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